LAT-NET
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- $73 - $737
- Product name: LAT-NET
- CAS: 607351-44-0
- MF: C25H39NO4
- MW: 417.58
- EINECS:
- MDL Number:MFCD03412001
- Synonyms:LATANOPROST ETHYL AMIDE;LAT-NET;N-ETHYL-9ALPHA, 11ALPHA, 15R-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR PROST 5Z-EN-1-AMIDE;Bimatoprost Impurity 20;(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-N-ethylhept-5-enamide;13,14-Dihydro Bimatoprost;5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-N-ethyl-, (5Z)-
5 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- TRC
Package
- 1mg
- 5mg
- 10mg
- ManufacturerAK Scientific
- Product number6557CR
- Product descriptionLatanoprostethylamide
- Packaging10mg
- Price$737
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16822
- Product descriptionLatanoprost ethyl amide ≥98%
- Packaging1mg
- Price$73
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16822
- Product descriptionLatanoprost ethyl amide ≥98%
- Packaging5mg
- Price$324
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16822
- Product descriptionLatanoprost ethyl amide ≥98%
- Packaging10mg
- Price$575
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberD450468
- Product description13,14-DihydroBimatoprost
- Packaging1mg
- Price$155
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 6557CR | Latanoprostethylamide | 10mg | $737 | 2021-12-16 | Buy |
| Cayman Chemical | 16822 | Latanoprost ethyl amide ≥98% | 1mg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 16822 | Latanoprost ethyl amide ≥98% | 5mg | $324 | 2024-03-01 | Buy |
| Cayman Chemical | 16822 | Latanoprost ethyl amide ≥98% | 10mg | $575 | 2024-03-01 | Buy |
| TRC | D450468 | 13,14-DihydroBimatoprost | 1mg | $155 | 2021-12-16 | Buy |
Properties
Boiling point :640.9±55.0 °C(Predicted)
Density :1.095±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 50 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 200 μg/ml
pka :14.84±0.70(Predicted)
Density :1.095±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 50 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 200 μg/ml
pka :14.84±0.70(Predicted)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | ||||||||||||||||||||||||||||||||||||||||
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Description
Latanoprost ethyl amide (Lat-NEt) is a latanoprost analog in which the C-1 carboxyl group has been modified to an N-ethyl amide. Prostaglandin esters have been shown to have ocular hypotensive activity. Prostaglandin N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs. Although it has been claimed that prostaglandin ethyl amides are not converted to the free acids in vivo, studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 μg/g corneal tissue/hr. Lat-NEt would be expected to show the typical intraocular effects of Latanoprost free acid, but with the much slower hydrolysis pharmacokinetics of the prostaglandin N-amides.Related product price
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