5-Aminosalicylic acid
|
- $5 - $1880
- Product name: 5-Aminosalicylic acid
- CAS: 89-57-6
- MF: C7H7NO3
- MW: 153.14
- EINECS:201-919-1
- MDL Number:MFCD00007877
- Synonyms:5-AMINOSALICYLIC ACID;5-AS;LABOTEST-BB LT00134704;IFLAB-BB F1918-0003;BENZOIC ACID, 5-AMINO-2-HYDROXY-;M-AMINOSALICYLIC ACID;5-Amino-2-hydroxybenzoic acid~Mesalamine;5-Aminosalicylic acid;5-Amino-2-hydroxybenzoic acid; 5-ASA
49 prices
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Brand
- AK Scientific
- Alfa Aesar
- Ambeed
- ApexBio Technology
- Aronis compounds
- Atlantic Research Chemicals
- Cayman Chemical
- Chem-Impex
- ChemScene
- Chemtos
- Crysdot
- CSNpharm
- Frontier Specialty Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 1mg
- 10mg
- 100mg
- 200mg
- 1g
- 5g
- 25mg
- y0001574
- 125MG
- 10g
- 50mg
- y0000297
- 100g
- 500g
- 1kg
- 1000g
- 10mM(in 1mL DMSO)
- 25g
- 50g
- 250G
- 25gm:
- ManufacturerAK Scientific
- Product numberJ93598
- Product description5-Aminosalicylic acid
- Packaging25g
- Price$15
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberG374
- Product description5-Aminosalicylic acid
- Packaging100g
- Price$54
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberB23970
- Product description5-Aminosalicylic acid, 95%
- Packaging100g
- Price$52.8
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberB23970
- Product description5-Aminosalicylic acid, 95%
- Packaging500g
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105320
- Product description5-Amino-2-hydroxybenzoic acid 98+%
- Packaging50mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105320
- Product description5-Amino-2-hydroxybenzoic acid 98+%
- Packaging10g
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105320
- Product description5-Amino-2-hydroxybenzoic acid 98+%
- Packaging25g
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105320
- Product description5-Amino-2-hydroxybenzoic acid 98+%
- Packaging100g
- Price$20
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105320
- Product description5-Amino-2-hydroxybenzoic acid 98+%
- Packaging500g
- Price$82
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105320
- Product description5-Amino-2-hydroxybenzoic acid 98+%
- Packaging1kg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1969
- Product descriptionMesalamine
- Packaging10g
- Price$37
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1969
- Product descriptionMesalamine
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAronis compounds
- Product numberBBC/193
- Product description5-Amino-2-hydroxybenzoic acid
- Packaging1g
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAtlantic Research Chemicals
- Product numberCA001128
- Product description5-Amino-2-hydroxybenzoic acid 95%
- Packaging25gm:
- Price$16.97
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number70265
- Product description5-Aminosalicylic Acid ≥99%
- Packaging10g
- Price$16
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number70265
- Product description5-Aminosalicylic Acid ≥99%
- Packaging25g
- Price$33
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | J93598 | 5-Aminosalicylic acid | 25g | $15 | 2021-12-16 | Buy |
| AK Scientific | G374 | 5-Aminosalicylic acid | 100g | $54 | 2021-12-16 | Buy |
| Alfa Aesar | B23970 | 5-Aminosalicylic acid, 95% | 100g | $52.8 | 2021-12-16 | Buy |
| Alfa Aesar | B23970 | 5-Aminosalicylic acid, 95% | 500g | $165 | 2021-12-16 | Buy |
| Ambeed | A105320 | 5-Amino-2-hydroxybenzoic acid 98+% | 50mg | $5 | 2021-12-16 | Buy |
| Ambeed | A105320 | 5-Amino-2-hydroxybenzoic acid 98+% | 10g | $6 | 2021-12-16 | Buy |
| Ambeed | A105320 | 5-Amino-2-hydroxybenzoic acid 98+% | 25g | $8 | 2021-12-16 | Buy |
| Ambeed | A105320 | 5-Amino-2-hydroxybenzoic acid 98+% | 100g | $20 | 2021-12-16 | Buy |
| Ambeed | A105320 | 5-Amino-2-hydroxybenzoic acid 98+% | 500g | $82 | 2021-12-16 | Buy |
| Ambeed | A105320 | 5-Amino-2-hydroxybenzoic acid 98+% | 1kg | $150 | 2021-12-16 | Buy |
| ApexBio Technology | B1969 | Mesalamine | 10g | $37 | 2021-12-16 | Buy |
| ApexBio Technology | B1969 | Mesalamine | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| Aronis compounds | BBC/193 | 5-Amino-2-hydroxybenzoic acid | 1g | $133 | 2021-12-16 | Buy |
| Atlantic Research Chemicals | CA001128 | 5-Amino-2-hydroxybenzoic acid 95% | 25gm: | $16.97 | 2021-12-16 | Buy |
| Cayman Chemical | 70265 | 5-Aminosalicylic Acid ≥99% | 10g | $16 | 2024-03-01 | Buy |
| Cayman Chemical | 70265 | 5-Aminosalicylic Acid ≥99% | 25g | $33 | 2024-03-01 | Buy |
Properties
Melting point :275-280 °C (dec.) (lit.)
Boiling point :276.03°C (rough estimate)
Density :1.3585 (rough estimate)
vapor pressure :0Pa at 25℃
refractive index :1.5500 (estimate)
Flash point :279-281°C
storage temp. :2-8°C
solubility :Soluble in dimethyl sulfoxide.
pka :2.74, 5.84(at 25℃)
form :tablets
color :off-white to gray
PH :4.0-4.1 (0.8g/l, H2O, 20℃)
PH Range :Non-B uorescence (3.1) to light green B uorescence (4.4)
Water Solubility :<0.1 g/100 mL at 21 ºC
Decomposition :279-281 ºC
Merck :14,5904
BRN :2090421
BCS Class :4
Stability :Stable. Incompatible with acids, acid anhydrides, acid chlorides, chloroformates, strong oxidizing agents.
Major Application :Detergent, hair dyes, prevention of colorectal cancer, treating inflammatory bowel disease, autoimmune disorders, gastrointestinal inflammation, chemokine-mediated diseases, mucosal tissue disorder, sleep disorders, rectoanal tenesmus, ulcerative colitis
InChIKey :KBOPZPXVLCULAV-UHFFFAOYSA-N
LogP :0.98 at 25℃
CAS DataBase Reference :89-57-6(CAS DataBase Reference)
NIST Chemistry Reference :Mesalamine(89-57-6)
EPA Substance Registry System :Benzoic acid, 5-amino-2-hydroxy- (89-57-6)
Boiling point :276.03°C (rough estimate)
Density :1.3585 (rough estimate)
vapor pressure :0Pa at 25℃
refractive index :1.5500 (estimate)
Flash point :279-281°C
storage temp. :2-8°C
solubility :Soluble in dimethyl sulfoxide.
pka :2.74, 5.84(at 25℃)
form :tablets
color :off-white to gray
PH :4.0-4.1 (0.8g/l, H2O, 20℃)
PH Range :Non-B uorescence (3.1) to light green B uorescence (4.4)
Water Solubility :<0.1 g/100 mL at 21 ºC
Decomposition :279-281 ºC
Merck :14,5904
BRN :2090421
BCS Class :4
Stability :Stable. Incompatible with acids, acid anhydrides, acid chlorides, chloroformates, strong oxidizing agents.
Major Application :Detergent, hair dyes, prevention of colorectal cancer, treating inflammatory bowel disease, autoimmune disorders, gastrointestinal inflammation, chemokine-mediated diseases, mucosal tissue disorder, sleep disorders, rectoanal tenesmus, ulcerative colitis
InChIKey :KBOPZPXVLCULAV-UHFFFAOYSA-N
LogP :0.98 at 25℃
CAS DataBase Reference :89-57-6(CAS DataBase Reference)
NIST Chemistry Reference :Mesalamine(89-57-6)
EPA Substance Registry System :Benzoic acid, 5-amino-2-hydroxy- (89-57-6)
Safety Information
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Description
5-Aminosalicylic acid (5-ASA) is a metabolite and potential pharmacologically active component of sulphasalazine, a drug used in the treatment of Crohn’s disease and ulcerative colitis. However, the mechanism by which this drug works has not been established. In whole blood assays, 5-ASA proves to be a weak, non-selective inhibitor of both COX-1 and COX-2 with IC50 values of 410 and 61 μM, respectively. In ionophore-stimulated colonic mucosal cells, 1 mM 5-ASA does not inhibit prostaglandin E2 (PGE2) production, but does reduce leukotriene B4 (LTB4) synthesis approx. 50%. In ionophore-stimulated human leukocytes, 400 μM 5-ASA reduces LTB4 production approximately 20%. 5-ASA does not inhibit 15-hydroxy PGDH at concentrations up to 50 μM.More related product prices
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Suppliers and manufacturers
Zhejiang Kinso Pharmaceuticals Co., LTD.
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