Alsterpaullone
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- $68 - $3219
- Product name: Alsterpaullone
- CAS: 237430-03-4
- MF: C16H11N3O3
- MW: 293.28
- EINECS:
- MDL Number:MFCD02683579
- Synonyms:ALSTERPAULLONE;9-NITRO-7,12-DIHYDROINDOLO-[3,2-D][1]BENZAZEPIN-6(5H)-ONE;9-NITRO-7,12-DIHYDROINDOLO-[3,2-D][1]BENZAZEPIN-6(5)-ONE;9-nitro-7,12-dihydrobenzo[2,3]azepino[4,5-b]indol-6(5H)-one;9-Nitropaullone;NSC 705701;Alsterpaullone (9-Nitropaullone;ALSTERPAULLONE (9-NITROPAULLONE;NSC 705701)
21 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 2.5mg
- 5mg
- 10mg
- 100mg
- 250mg
- 1g
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0036-M005
- Product descriptionAlsterpaullone ≥98%(NMR)
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2336BB
- Product descriptionAlsterpaullone
- Packaging1mg
- Price$174
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2336BB
- Product descriptionAlsterpaullone
- Packaging5mg
- Price$434
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA310955
- Product description7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one 98%
- Packaging5mg
- Price$296
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA310955
- Product description7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one 98%
- Packaging250mg
- Price$1347
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA310955
- Product description7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one 98%
- Packaging1g
- Price$3219
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7855
- Product descriptionAlsterpaullone
- Packaging1mg
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7855
- Product descriptionAlsterpaullone
- Packaging5mg
- Price$322
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545894
- Product descriptionAlsterpaullone >98%
- Packaging1mg
- Price$164.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545894
- Product descriptionAlsterpaullone >98%
- Packaging5mg
- Price$430.1
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14428
- Product descriptionAlsterpaullone ≥98%
- Packaging1mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14428
- Product descriptionAlsterpaullone ≥98%
- Packaging5mg
- Price$302
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0028454
- Product descriptionAlsterpaullone ≥98.0%
- Packaging10mg
- Price$2250
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN22673
- Product descriptionAlsterpaullone
- Packaging1mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN22673
- Product descriptionAlsterpaullone
- Packaging5mg
- Price$370
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9838
- Product descriptionAlsterpaullone >98%
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-0036-M005 | Alsterpaullone ≥98%(NMR) | 5mg | $120 | 2021-12-16 | Buy |
| AK Scientific | 2336BB | Alsterpaullone | 1mg | $174 | 2021-12-16 | Buy |
| AK Scientific | 2336BB | Alsterpaullone | 5mg | $434 | 2021-12-16 | Buy |
| Ambeed | A310955 | 7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one 98% | 5mg | $296 | 2021-12-16 | Buy |
| Ambeed | A310955 | 7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one 98% | 250mg | $1347 | 2021-12-16 | Buy |
| Ambeed | A310955 | 7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one 98% | 1g | $3219 | 2021-12-16 | Buy |
| ApexBio Technology | B7855 | Alsterpaullone | 1mg | $72 | 2021-12-16 | Buy |
| ApexBio Technology | B7855 | Alsterpaullone | 5mg | $322 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545894 | Alsterpaullone >98% | 1mg | $164.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545894 | Alsterpaullone >98% | 5mg | $430.1 | 2021-12-16 | Buy |
| Cayman Chemical | 14428 | Alsterpaullone ≥98% | 1mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 14428 | Alsterpaullone ≥98% | 5mg | $302 | 2024-03-01 | Buy |
| ChemScene | CS-0028454 | Alsterpaullone ≥98.0% | 10mg | $2250 | 2021-12-16 | Buy |
| CSNpharm | CSN22673 | Alsterpaullone | 1mg | $220 | 2021-12-16 | Buy |
| CSNpharm | CSN22673 | Alsterpaullone | 5mg | $370 | 2021-12-16 | Buy |
| DC Chemicals | DC9838 | Alsterpaullone >98% | 100mg | $650 | 2021-12-16 | Buy |
Properties
Melting point :>330℃
Boiling point :651.5±45.0 °C(Predicted)
Density :1.461±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble
form :powder
pka :14.18±0.20(Predicted)
color :brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Boiling point :651.5±45.0 °C(Predicted)
Density :1.461±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble
form :powder
pka :14.18±0.20(Predicted)
color :brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
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Description
Alsterpaullone is a derivative of kenpaullone , an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3β (GSK3β). With slightly improved potency over kenpaullone, alsterpaullone selectively inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and GSK3α/β with IC50 values of 35, 15, 200, 40, and 4 nM, respectively. Alsterpaullone has been used to inhibit the cytosolic degradation of β-catenin to alter the canonical Wnt signaling pathway in primary axis patterning, to reduce tau phosphorylation in an effort to modify neuropathological events associated with Alzheimer’s disease, and to alter cell proliferation or protein expression in various diseases.More related product prices
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