Alsterpaullone suppliers
ALSTERPAULLONE
- CAS:
- 237430-03-4
- MF:
- C16H11N3O3
- MW:
- 293.28
Suppliers by country/region
Company Type
Properties
- Melting point:
- >330℃
- Boiling point:
- 651.5±45.0 °C(Predicted)
- Density
- 1.461±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble
- form
- powder
- pka
- 14.18±0.20(Predicted)
- color
- brown
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
Use
Alsterpaullone is a derivative of kenpaullone , an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3β (GSK3β). With slightly improved potency over kenpaullone, alsterpaullone selectively inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and GSK3α/β with IC50 values of 35, 15, 200, 40, and 4 nM, respectively. Alsterpaullone has been used to inhibit the cytosolic degradation of β-catenin to alter the canonical Wnt signaling pathway in primary axis patterning, to reduce tau phosphorylation in an effort to modify neuropathological events associated with Alzheimer’s disease, and to alter cell proliferation or protein expression in various diseases.
76 supplier list of "ALSTERPAULLONE"
- Product Name:ALSTERPAULLONE
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:Alsterpaullone
- Products Intro:Purity: >=98% | Package: 50mg | CustNote: BOC Sciences also provides custom synthesis services for Alsterpaullone.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:ALSTERPAULLONE
- Products Intro:Purity: Min98% HPLC/GC | Package: 1g;1USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Methyl 3-amino-2-fluorobenzoate
- Product Name:Alsterpaullone
- Products Intro:Purity: >95% | CustNote: https://www.alfa-chemistry.com/cas_237430-03-4.htm
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Active Pharmaceutical Ingredient (API),Insect Pheromone,Boronic Compounds,Material & Chemicals,Lipid Compounds
- Product Name:ALSTERPAULLONE
- Products Intro:Purity: 97% Min. | CustNote: MC447681
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: 2432-11-3,1052686-50-6,2198-53-0,3769-42-4,83647-42-1
- Product Name:Alsterpaullone
- Products Intro:Purity: 98% | Package: $256.9/5mg;$1156.9/25mg;$1440.9/50mg;$2305.9/100mg;Bulk package | CustNote: 98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
-
1mg$119.00
- Product Name:Alsterpaullone - CAS 237430-03-4 - Calbiochem
- Products Intro:Brand: Sigma-Aldrich | Product Number: 126870 | Purity: A cell-permeable, potent, reversible, and ATP competitive inhibitor of GSK-3β (IC = 4 nM) and Cdk1/cyclin B (IC = 35 nM).
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: cof,mof
-
1 mg$55.005 mg$248.00
- Product Name:Alsterpaullone
- Products Intro:Brand: Caymanchem | Product Number: 14428 | Purity: ≥98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: cof,mof
![7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one](https://img.chemicalbook.com/CompanyLogo/TocrisBioscience.png)
-
10 mg$199.00
- Product Name:7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one
- Products Intro:Brand: Tocris Bioscience | Product Number: 6400 | Purity: ≥98% (HPLC)
- Company Type: Trader
- Country/Region: UNITED KINGDOM
- Main Products: cof,mof
-
100 mg$650.00
- Product Name:Alsterpaullone
- Products Intro:Brand：dcchemicals | Product Number：DC9838 | Purity：>98%
- Company Type: Trader
- Country/Region: UNITED STATES