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ChemicalBook >> CAS DataBase List >> BAM15

BAM15

BAM15 price.
  • $32 - $1500
  • Product name: BAM15
  • CAS: 210302-17-3
  • MF: C16H10F2N6O
  • MW: 340.29
  • EINECS:201-118-7
  • MDL Number:MFCD00373912
  • Synonyms:BAM15;N,N'-bis(2-fluorophenyl)[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine;CS-2890;[1,2,5]Oxadiazolo[3,4-b]pyrazine-5,6-diamine, N5,N6-bis(2-fluorophenyl)-;BAM15 >=98% (HPLC);BAM 15 (N5,N6-bis(2-Fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine);inhibit,BAM-15,Inhibitor,BAM 15,BAM15,Mitochondrial Metabolism
24 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 50
  • 10
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAK Scientific
  • Product number5649CC
  • Product description5-N,6-N-Bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine
  • Packaging5mg
  • Price$201
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA924230
  • Product descriptionBAM15 99+%
  • Packaging5mg
  • Price$211
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA924230
  • Product descriptionBAM15 99+%
  • Packaging10mg
  • Price$369
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA924230
  • Product descriptionBAM15 99+%
  • Packaging25mg
  • Price$646
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0009220
  • Product descriptionBAM-15 95.00%
  • Packaging5MG
  • Price$450.09
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17811
  • Product descriptionBAM15 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17811
  • Product descriptionBAM15 ≥98%
  • Packaging5mg
  • Price$78
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17811
  • Product descriptionBAM15 ≥98%
  • Packaging10mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17811
  • Product descriptionBAM15 ≥98%
  • Packaging25mg
  • Price$305
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0033152
  • Product descriptionBAM15 99.26%
  • Packaging5mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0033152
  • Product descriptionBAM15 99.26%
  • Packaging10mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0033152
  • Product descriptionBAM15 99.26%
  • Packaging25mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0033152
  • Product descriptionBAM15 99.26%
  • Packaging50mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0033152
  • Product descriptionBAM15 99.26%
  • Packaging100mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD35000156
  • Product descriptionBAM15 98%
  • Packaging25mg
  • Price$306
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC32783
  • Product descriptionBAM15
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 5649CC 5-N,6-N-Bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine 5mg $201 2021-12-16 Buy
Ambeed A924230 BAM15 99+% 5mg $211 2021-12-16 Buy
Ambeed A924230 BAM15 99+% 10mg $369 2021-12-16 Buy
Ambeed A924230 BAM15 99+% 25mg $646 2021-12-16 Buy
American Custom Chemicals Corporation BRS0009220 BAM-15 95.00% 5MG $450.09 2021-12-16 Buy
Cayman Chemical 17811 BAM15 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 17811 BAM15 ≥98% 5mg $78 2024-03-01 Buy
Cayman Chemical 17811 BAM15 ≥98% 10mg $139 2024-03-01 Buy
Cayman Chemical 17811 BAM15 ≥98% 25mg $305 2024-03-01 Buy
ChemScene CS-0033152 BAM15 99.26% 5mg $75 2021-12-16 Buy
ChemScene CS-0033152 BAM15 99.26% 10mg $135 2021-12-16 Buy
ChemScene CS-0033152 BAM15 99.26% 25mg $250 2021-12-16 Buy
ChemScene CS-0033152 BAM15 99.26% 50mg $400 2021-12-16 Buy
ChemScene CS-0033152 BAM15 99.26% 100mg $600 2021-12-16 Buy
Crysdot CD35000156 BAM15 98% 25mg $306 2021-12-16 Buy
DC Chemicals DC32783 BAM15 100mg $450 2021-12-16 Buy

Properties

Boiling point :421.7±55.0 °C(Predicted)
Density :1.548±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (35 mg/ml)
pka :-2.40±0.50(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P201 Obtain special instructions before use.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.

Description

Typical mitochondrial uncouplers are lipophilic weak acids that increase proton transport into the mitochondrial matrix through an ATP synthase-independent pathway, thereby uncoupling nutrient oxidation from ATP production. These chemicals are used to determine rate of cellular respiration and have antioxidant effects that protect from ischemia-reperfusion injury. Most proton transporter uncouplers, however, exhibit off-target activity that can lead to undesired effects, including plasma membrane depolarization, mitochondrial inhibition, and cytotoxicity. BAM15 is a mitochondrial protonophore uncoupler that does not depolarize the plasma membrane and protects mice from acute renal ischemic-reperfusion injury. In comparison to FCCP , 1-10 μM BAM15 was shown to increase oxygen flux with equal potency as the classic uncoupler, while displaying a higher maximum rate of mitochondrial respiration and less cytotoxicity.

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