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ChemicalBook >> CAS DataBase List >> (+/-)-BLEBBISTATIN

(+/-)-BLEBBISTATIN

(+/-)-BLEBBISTATIN price.
  • $70 - $1960
  • Product name: (+/-)-BLEBBISTATIN
  • CAS: 674289-55-5
  • MF: C18H16N2O2
  • MW: 292.33
  • EINECS:
  • MDL Number:MFCD04113775
  • Synonyms:(R)-(+)-BLEBBISTATIN;(3AS)-(-)-1,2,3,3A-TETRAHYDRO-3A-HYDROXY-6-METHYL-1-PHENYL-4H-PYRROLO[2,3-B]QUINOLIN-4-ONE;(+/-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE;(+/-)-1,2,3,3A-TETRAHYDRO-3A-HYDROXY-6-METHYL-1-PHENYL-4H-PYRROLO[2,3-B]QUINOLIN-4-ONE;(+/-)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-β]-7-methylquinolin-4-one;1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-β]quinolin-4-one;(3aS)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-β]quinolin-4-one;(3aR)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-β]quinolin-4-one
21 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 5MG
  • 1
  • 1mg
  • 10MG
  • 20mg
  • 25mg
  • 50mg
  • 100MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001058
  • Product description(+/-)-BLEBBISTATIN 95.00%
  • Packaging5MG
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001058
  • Product description(+/-)-BLEBBISTATIN 95.00%
  • Packaging10MG
  • Price$620
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001058
  • Product description(+/-)-BLEBBISTATIN 95.00%
  • Packaging100MG
  • Price$1960
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6847
  • Product description(±)-Blebbistatin
  • Packaging1mg
  • Price$402
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2718
  • Product description(±)-Blebbistatin 99%
  • Packaging5mg
  • Price$104.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB18838
  • Product description(+/-)-Blebbistatin
  • Packaging50mg
  • Price$437.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB18838
  • Product description(+/-)-Blebbistatin
  • Packaging10mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB18838
  • Product description(+/-)-Blebbistatin
  • Packaging20mg
  • Price$800
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13186
  • Product description(±)-Blebbistatin ≥98%
  • Packaging5mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13186
  • Product description(±)-Blebbistatin ≥98%
  • Packaging10mg
  • Price$189
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13186
  • Product description(±)-Blebbistatin ≥98%
  • Packaging25mg
  • Price$336
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13186
  • Product description(±)-Blebbistatin ≥98%
  • Packaging50mg
  • Price$629
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0007920
  • Product descriptionBlebbistatin 99.64%
  • Packaging1mg
  • Price$255
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11074782
  • Product description(±)bebbistatin 97%
  • Packaging50mg
  • Price$430
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11074782
  • Product description(±)bebbistatin 97%
  • Packaging100mg
  • Price$825
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number7537
  • Product description(+/-)-Blebbistatin
  • Packaging50mg
  • Price$1880
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation INB0001058 (+/-)-BLEBBISTATIN 95.00% 5MG $550 2021-12-16 Buy
American Custom Chemicals Corporation INB0001058 (+/-)-BLEBBISTATIN 95.00% 10MG $620 2021-12-16 Buy
American Custom Chemicals Corporation INB0001058 (+/-)-BLEBBISTATIN 95.00% 100MG $1960 2021-12-16 Buy
ApexBio Technology B6847 (±)-Blebbistatin 1mg $402 2021-12-16 Buy
Axon Medchem Axon2718 (±)-Blebbistatin 99% 5mg $104.5 2021-12-16 Buy
Biosynth Carbosynth FB18838 (+/-)-Blebbistatin 50mg $437.5 2021-12-16 Buy
Biosynth Carbosynth FB18838 (+/-)-Blebbistatin 10mg $450 2021-12-16 Buy
Biosynth Carbosynth FB18838 (+/-)-Blebbistatin 20mg $800 2021-12-16 Buy
Cayman Chemical 13186 (±)-Blebbistatin ≥98% 5mg $86 2024-03-01 Buy
Cayman Chemical 13186 (±)-Blebbistatin ≥98% 10mg $189 2024-03-01 Buy
Cayman Chemical 13186 (±)-Blebbistatin ≥98% 25mg $336 2024-03-01 Buy
Cayman Chemical 13186 (±)-Blebbistatin ≥98% 50mg $629 2024-03-01 Buy
ChemScene CS-0007920 Blebbistatin 99.64% 1mg $255 2021-12-16 Buy
Crysdot CD11074782 (±)bebbistatin 97% 50mg $430 2021-12-16 Buy
Crysdot CD11074782 (±)bebbistatin 97% 100mg $825 2021-12-16 Buy
Medical Isotopes, Inc. 7537 (+/-)-Blebbistatin 50mg $1880 2021-12-16 Buy

Properties

Melting point :210-212°C
Boiling point :507.3±60.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :Chloroform (Slightly), Dichloromethane, DMSO, Ethyl Acetate, Methanol
form :Bright yellow solid.
pka :11.15±0.20(Predicted)
color :Yellow
CAS DataBase Reference :674289-55-5

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(±)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50 = 0.5-5.0 μM), while poorly inhibiting smooth muscle myosin (IC50 = 80 μM). Through these effects, blebbistatin blocks apoptosis-related bleb formation, directed cell migration and cytokinesis in vertebrate cells. Blebbistatin is inactivated by UV light, which may be particularly important in fluorescent cell imaging applications. Purified enantiomers of Blebbistatin are also available from Cayman ((?)-Blebbistatin - ).

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