BMS-754807
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- $44 - $3282.7
- Product name: BMS-754807
- CAS: 1001350-96-4
- MF: C23H24FN9O
- MW: 461.49
- EINECS:-0
- MDL Number:MFCD18633202
- Synonyms:(2S)-1-[4-[(5-Cyclopropyl-1H-pyrazol-3-yl)aMino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoropyridin-3-yl)-2-Methylpyrrolidine-2-carboxaMide;(S)-1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)aMino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-Methylpyrrolidine-2-carboxaMide;BMS-754807;(2S)-1-[4-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methyl-2-pyrrolidinecarboxamide;(S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide;(2S)-1-[4-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methyl-2-pyrrolidinecarboxamide BMS 754807;BMS 754807 (2S)-1-[4-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methyl-2-pyrrolidinecarboxamide;(S)-1-(1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-2-methylpyrrolidin-2-yl)-2-((6-fluoropyridin-3-yl)amino)ethanone
24 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 2mg
- 10mM(in 1mL DMSO)
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2280AH
- Product descriptionBMS-754807
- Packaging2mg
- Price$199
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001419
- Product descriptionBMS-754807 95.00%
- Packaging5MG
- Price$503.06
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1185
- Product descriptionBMS-754807
- Packaging5mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1185
- Product descriptionBMS-754807
- Packaging10mM(in 1mL DMSO)
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1185
- Product descriptionBMS-754807
- Packaging25mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1185
- Product descriptionBMS-754807
- Packaging100mg
- Price$700
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60243
- Product descriptionBMS-754807
- Packaging10mg
- Price$238
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146136
- Product descriptionBMS754807 >99%
- Packaging100mg
- Price$912.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146136
- Product descriptionBMS754807 >99%
- Packaging250mg
- Price$1654.1
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146136
- Product descriptionBMS754807 >99%
- Packaging1g
- Price$3282.7
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB64960
- Product descriptionBMS 754807
- Packaging10mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB64960
- Product descriptionBMS 754807
- Packaging50mg
- Price$333
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17505
- Product descriptionBMS 754807 ≥98%
- Packaging10mg
- Price$321
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17505
- Product descriptionBMS 754807 ≥98%
- Packaging5mg
- Price$202
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17505
- Product descriptionBMS 754807 ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0608
- Product descriptionBMS-754807 99.76%
- Packaging5mg
- Price$72
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2280AH | BMS-754807 | 2mg | $199 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001419 | BMS-754807 95.00% | 5MG | $503.06 | 2021-12-16 | Buy |
| ApexBio Technology | A1185 | BMS-754807 | 5mg | $65 | 2021-12-16 | Buy |
| ApexBio Technology | A1185 | BMS-754807 | 10mM(in 1mL DMSO) | $90 | 2021-12-16 | Buy |
| ApexBio Technology | A1185 | BMS-754807 | 25mg | $250 | 2021-12-16 | Buy |
| ApexBio Technology | A1185 | BMS-754807 | 100mg | $700 | 2021-12-16 | Buy |
| Arctom | CFN60243 | BMS-754807 | 10mg | $238 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146136 | BMS754807 >99% | 100mg | $912.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146136 | BMS754807 >99% | 250mg | $1654.1 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146136 | BMS754807 >99% | 1g | $3282.7 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB64960 | BMS 754807 | 10mg | $95 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB64960 | BMS 754807 | 50mg | $333 | 2021-12-16 | Buy |
| Cayman Chemical | 17505 | BMS 754807 ≥98% | 10mg | $321 | 2024-03-01 | Buy |
| Cayman Chemical | 17505 | BMS 754807 ≥98% | 5mg | $202 | 2024-03-01 | Buy |
| Cayman Chemical | 17505 | BMS 754807 ≥98% | 1mg | $44 | 2024-03-01 | Buy |
| ChemScene | CS-0608 | BMS-754807 99.76% | 5mg | $72 | 2021-12-16 | Buy |
Properties
Density :1.58
storage temp. :room temp
solubility :≥23.05 mg/mL in DMSO; insoluble in H2O; ≥27.75 mg/mL in EtOH
form :powder
color :white to beige
optical activity :[α]/D -86 to -96°, c = 1 in methanol
storage temp. :room temp
solubility :≥23.05 mg/mL in DMSO; insoluble in H2O; ≥27.75 mg/mL in EtOH
form :powder
color :white to beige
optical activity :[α]/D -86 to -96°, c = 1 in methanol
Safety Information
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Description
BMS 754807 is a reversible, orally bioavailable dual inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (InsR) tyrosine kinases (IC50s = 1.8 and 1.7 nM, respectively). It has minimal effect against an array of other tyrosine and serine/threonine kinases. BMS 754807 inhibits cell proliferation or induces apoptosis in a variety of cancer cells in vitro. It inhibits the growth of tumor xenografts in mice and this effect is often enhanced by combination therapy with other chemotherapeutics. Predictive biomarkers, including elevated IGF-1R expression, for effectiveness of BMS 754807 have been delineated.Related product price
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