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ChemicalBook >> CAS DataBase List >> BRYOSTATIN 1

BRYOSTATIN 1

BRYOSTATIN 1 price.
  • $187 - $945.01
  • Product name: BRYOSTATIN 1
  • CAS: 83314-01-6
  • MF: C47H68O17
  • MW: 905.03
  • EINECS:
  • MDL Number:MFCD00893832
  • Synonyms:BRYOSTATIN 1;BRYO 1;BRYOSTATIN;bryostatin1,0;(26R)-Bryostatin 1;NSC-339555;(1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl2,4-octadienoicacidester;2,4-Octadienoic acid, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(acetyloxy)-1,11,21-trihydroxy-17-(1R)-1-hydroxyethyl-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo21.3.1.13,7.111,15nonacos-8-en
8 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • Usbiological
Package
  • 10ug
  • 10μG
  • 25μG
  • 10U
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001772
  • Product descriptionBRYOSTATIN 1 95.00%
  • Packaging10μG
  • Price$720.48
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0001772
  • Product descriptionBRYOSTATIN 1 95.00%
  • Packaging25μG
  • Price$945.01
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7033
  • Product descriptionBryostatin 1
  • Packaging10ug
  • Price$266
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0025440
  • Product descriptionBryostatin 1
  • Packaging10ug
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberB7431
  • Product descriptionBryostatin 1 ≥99%, solid
  • Packaging10μg
  • Price$228
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number203811
  • Product descriptionBryostatin 1 - CAS 83314-01-6 - Calbiochem A macrocyclic lactone with antitumor properties.
  • Packaging10μG
  • Price$246
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number2383
  • Product descriptionBryostatin 1 ≥98%(HPLC)
  • Packaging10U
  • Price$187
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number254820
  • Product descriptionBryostatin 1
  • Packaging10ug
  • Price$432
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0001772 BRYOSTATIN 1 95.00% 10μG $720.48 2021-12-16 Buy
American Custom Chemicals Corporation API0001772 BRYOSTATIN 1 95.00% 25μG $945.01 2021-12-16 Buy
ApexBio Technology B7033 Bryostatin 1 10ug $266 2021-12-16 Buy
ChemScene CS-0025440 Bryostatin 1 10ug $480 2021-12-16 Buy
Sigma-Aldrich B7431 Bryostatin 1 ≥99%, solid 10μg $228 2024-03-01 Buy
Sigma-Aldrich 203811 Bryostatin 1 - CAS 83314-01-6 - Calbiochem A macrocyclic lactone with antitumor properties. 10μG $246 2024-03-01 Buy
Tocris 2383 Bryostatin 1 ≥98%(HPLC) 10U $187 2021-12-16 Buy
Usbiological 254820 Bryostatin 1 10ug $432 2021-12-16 Buy

Properties

Melting point :230-235°
alpha :D25 +34.1° (c = 0.044 in methanol)
Boiling point :716.44°C (rough estimate)
Density :1.1245 (rough estimate)
refractive index :1.5940 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble
pka :11.10±0.70(Predicted)
form :solid
color :white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.

Description

Bryostatin 1 is structurally unique macrolactone marine natural product that binds to and modulates PKC (protein kinase C) activity at picomolar concentrations, but is not a carcinogen or a complete tumor promoter. In many systems it induces only a subset of the responses to PMA and blocks those which it does not induce. It is markedly more potent than PMA for translocating PKCδ and -ε. Animal tests have shown bryostatin 1 may alleviate brain damage after a stroke. Bryostatin 1 administered with lactacystin has displayed synergistically induced apoptosis in human leukemia cells.

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