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ChemicalBook >> CAS DataBase List >> CCT 018159

CCT 018159

CCT 018159 price.
  • $29 - $711
  • Product name: CCT 018159
  • CAS: 171009-07-7
  • MF: C20H20N2O4
  • MW: 352.38
  • EINECS:
  • MDL Number:MFCD00710300
  • Synonyms:CCT 018159;4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethyl-1,3-benzenediol;HSP90 Inhibitor, CCT018159 - CAS 171009-07-7 - Calbiochem;1,3-Benzenediol, 4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethyl-
15 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • CSNpharm
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 50
  • 1MG
  • 5mg
  • 10mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number9331BA
  • Product description4-[4-(2,3-Dihydro-1,4-benzodioxin-6-YL)-3-methyl-1H-pyrazol-5-YL]-6-ethylbenzene-1,3-diol
  • Packaging5mg
  • Price$179
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number9331BA
  • Product description4-[4-(2,3-Dihydro-1,4-benzodioxin-6-YL)-3-methyl-1H-pyrazol-5-YL]-6-ethylbenzene-1,3-diol
  • Packaging10mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004033
  • Product description4-(4-(2,3-DIHYDROBENZO[B][1,4]DIOXIN-6-YL)-5-METHYL-1H-PYRAZOL-3-YL)-6-ETHYLBENZENE-1,3-DIOL 95.00%
  • Packaging1MG
  • Price$137.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004033
  • Product description4-(4-(2,3-DIHYDROBENZO[B][1,4]DIOXIN-6-YL)-5-METHYL-1H-PYRAZOL-3-YL)-6-ETHYLBENZENE-1,3-DIOL 95.00%
  • Packaging5MG
  • Price$499.8
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3212
  • Product descriptionCCT018159
  • Packaging10mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012591
  • Product descriptionCCT018159 ≥98%
  • Packaging1mg
  • Price$29
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012591
  • Product descriptionCCT018159 ≥98%
  • Packaging5mg
  • Price$85
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012591
  • Product descriptionCCT018159 ≥98%
  • Packaging10mg
  • Price$156
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012591
  • Product descriptionCCT018159 ≥98%
  • Packaging50mg
  • Price$492
  • Updated2022-04-27
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN22743
  • Product descriptionCCT018159
  • Packaging10mg
  • Price$128
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number385920
  • Product descriptionHSP90 Inhibitor, CCT018159 - CAS 171009-07-7 - Calbiochem
    The HSP90 Inhibitor, CCT018159, also referenced under CAS 171009-07-7, controls the biological activity of HSP90.
  • Packaging5mg
  • Price$230
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number2435
  • Product descriptionCCT018159 ≥98%(HPLC)
  • Packaging10
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number2435
  • Product descriptionCCT018159 ≥98%(HPLC)
  • Packaging50
  • Price$711
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC227958
  • Product descriptionCCT018159
  • Packaging10mg
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number254905
  • Product descriptionCCT 018159
  • Packaging10mg
  • Price$409
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9331BA 4-[4-(2,3-Dihydro-1,4-benzodioxin-6-YL)-3-methyl-1H-pyrazol-5-YL]-6-ethylbenzene-1,3-diol 5mg $179 2021-12-16 Buy
AK Scientific 9331BA 4-[4-(2,3-Dihydro-1,4-benzodioxin-6-YL)-3-methyl-1H-pyrazol-5-YL]-6-ethylbenzene-1,3-diol 10mg $240 2021-12-16 Buy
American Custom Chemicals Corporation INB0004033 4-(4-(2,3-DIHYDROBENZO[B][1,4]DIOXIN-6-YL)-5-METHYL-1H-PYRAZOL-3-YL)-6-ETHYLBENZENE-1,3-DIOL 95.00% 1MG $137.55 2021-12-16 Buy
American Custom Chemicals Corporation INB0004033 4-(4-(2,3-DIHYDROBENZO[B][1,4]DIOXIN-6-YL)-5-METHYL-1H-PYRAZOL-3-YL)-6-ETHYLBENZENE-1,3-DIOL 95.00% 5MG $499.8 2021-12-16 Buy
ApexBio Technology C3212 CCT018159 10mg $145 2021-12-16 Buy
Cayman Chemical 10012591 CCT018159 ≥98% 1mg $29 2024-03-01 Buy
Cayman Chemical 10012591 CCT018159 ≥98% 5mg $85 2024-03-01 Buy
Cayman Chemical 10012591 CCT018159 ≥98% 10mg $156 2024-03-01 Buy
Cayman Chemical 10012591 CCT018159 ≥98% 50mg $492 2022-04-27 Buy
CSNpharm CSN22743 CCT018159 10mg $128 2021-12-16 Buy
Sigma-Aldrich 385920 HSP90 Inhibitor, CCT018159 - CAS 171009-07-7 - Calbiochem
The HSP90 Inhibitor, CCT018159, also referenced under CAS 171009-07-7, controls the biological activity of HSP90.
5mg $230 2024-03-01 Buy
Tocris 2435 CCT018159 ≥98%(HPLC) 10 $170 2021-12-16 Buy
Tocris 2435 CCT018159 ≥98%(HPLC) 50 $711 2021-12-16 Buy
TRC C227958 CCT018159 10mg $115 2021-12-16 Buy
Usbiological 254905 CCT 018159 10mg $409 2021-12-16 Buy

Properties

Boiling point :547.3±50.0 °C(Predicted)
Density :1.322±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
pka :8.84±0.48(Predicted)
form :White solid
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P501 Dispose of contents/container to..…

Description

CCT 018159 is a cell-permeable pyrazoloresorcinol compound that inhibits Hsp90 ATPase activity (IC50 = 3.2 μM and 6.6 μM against human HSP 90 beta and yeast Hsp90, respectively) by targeting the enzyme's N-terminal ATP binding site. CCT 018159 exhibits no detectable effects against human HSP 70 or topoisomerase II even at concentrations as high as 100 μM and inhibits a panel of 20 commonly studied kinases only at much higher concentrations. Unlike 17-AAG , the antitumor activity of CCT018159 is not affected by the expression of NQ01/DT-diaphorase or P-glycoprotein.

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