CCT251545
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- $49 - $2600
- Product name: CCT251545
- CAS: 1661839-45-7
- MF: C23H24ClN5O
- MW: 421.92
- EINECS:
- MDL Number:MFCD29472582
- Synonyms:CCT251545;8-[3-Chloro-5-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-4-pyridinyl]-2,8-diazaspiro[4.5]decan-1-one;LM-3773,CCT251545;8-(3-chloro-5-(4-(1-methyl-1H-pyrazol-4-yl)phenyl)pyridin-4-yl)-2,8-diazaspiro[4.5]decan-1-one;2,8-Diazaspiro[4.5]decan-1-one, 8-[3-chloro-5-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]-4-pyridinyl]-;CCT-251545;CCT 251545;CS-2537;inhibit,Wnt,CCT251545,Inhibitor,CCT-251545,CCT 251545
17 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 20mg
- 50mg
- 100mg
- 1g
- ManufacturerAK Scientific
- Product number0185DY
- Product description8-[3-Chloro-5-[4-(1-methylpyrazol-4-yl)phenyl]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one
- Packaging5mg
- Price$310
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5979
- Product descriptionCCT251545
- Packaging5mg
- Price$163
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5979
- Product descriptionCCT251545
- Packaging10mg
- Price$271
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5979
- Product descriptionCCT251545
- Packaging20mg
- Price$379
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18761
- Product descriptionCCT251545 ≥95%
- Packaging1mg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18761
- Product descriptionCCT251545 ≥95%
- Packaging5mg
- Price$190
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18761
- Product descriptionCCT251545 ≥95%
- Packaging10mg
- Price$333
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5359
- Product descriptionCCT251545 99.27%
- Packaging5mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5359
- Product descriptionCCT251545 99.27%
- Packaging10mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5359
- Product descriptionCCT251545 99.27%
- Packaging50mg
- Price$700
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5359
- Product descriptionCCT251545 99.27%
- Packaging100mg
- Price$1200
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003063
- Product descriptionCCT251545 98+%
- Packaging5mg
- Price$126
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003063
- Product descriptionCCT251545 98+%
- Packaging10mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003063
- Product descriptionCCT251545 98+%
- Packaging50mg
- Price$630
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003063
- Product descriptionCCT251545 98+%
- Packaging100mg
- Price$1050
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9968
- Product descriptionCCT251545 >98%
- Packaging1g
- Price$2600
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 0185DY | 8-[3-Chloro-5-[4-(1-methylpyrazol-4-yl)phenyl]pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one | 5mg | $310 | 2021-12-16 | Buy |
| ApexBio Technology | B5979 | CCT251545 | 5mg | $163 | 2021-12-16 | Buy |
| ApexBio Technology | B5979 | CCT251545 | 10mg | $271 | 2021-12-16 | Buy |
| ApexBio Technology | B5979 | CCT251545 | 20mg | $379 | 2021-12-16 | Buy |
| Cayman Chemical | 18761 | CCT251545 ≥95% | 1mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 18761 | CCT251545 ≥95% | 5mg | $190 | 2024-03-01 | Buy |
| Cayman Chemical | 18761 | CCT251545 ≥95% | 10mg | $333 | 2024-03-01 | Buy |
| ChemScene | CS-5359 | CCT251545 99.27% | 5mg | $110 | 2021-12-16 | Buy |
| ChemScene | CS-5359 | CCT251545 99.27% | 10mg | $190 | 2021-12-16 | Buy |
| ChemScene | CS-5359 | CCT251545 99.27% | 50mg | $700 | 2021-12-16 | Buy |
| ChemScene | CS-5359 | CCT251545 99.27% | 100mg | $1200 | 2021-12-16 | Buy |
| Crysdot | CD31003063 | CCT251545 98+% | 5mg | $126 | 2021-12-16 | Buy |
| Crysdot | CD31003063 | CCT251545 98+% | 10mg | $210 | 2021-12-16 | Buy |
| Crysdot | CD31003063 | CCT251545 98+% | 50mg | $630 | 2021-12-16 | Buy |
| Crysdot | CD31003063 | CCT251545 98+% | 100mg | $1050 | 2021-12-16 | Buy |
| DC Chemicals | DC9968 | CCT251545 >98% | 1g | $2600 | 2021-12-16 | Buy |
Properties
Boiling point :709.7±60.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :≥42.2 mg/mL in DMSO; insoluble in H2O; ≥2.33 mg/mL in EtOH with ultrasonic
form :solid
pka :15.81±0.20(Predicted)
color :White to off-white
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :≥42.2 mg/mL in DMSO; insoluble in H2O; ≥2.33 mg/mL in EtOH with ultrasonic
form :solid
pka :15.81±0.20(Predicted)
color :White to off-white
Safety Information
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Description
CCT251545 is an orally bioavailable inhibitor of Wnt signaling (IC50 = 5 nM). It is a potent and selective inhibitor of the human mediator complex-associated protein kinases Cdk8 and Cdk19. Through its effects on Cdk8 and Cdk19, CCT251545 alters Wnt pathway-regulated gene expression. It reduces tumor growth in COLO 205 human colon cancer xenografts after oral dosing (70 mg/kg bid) and in Wnt-dependent tumors.More related product prices
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