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ChemicalBook >> CAS DataBase List >> COCHLIOQUINONE A

COCHLIOQUINONE A

COCHLIOQUINONE A price.
  • $245 - $1390
  • Product name: COCHLIOQUINONE A
  • CAS: 32450-25-2
  • MF: C30H44O8
  • MW: 532.67
  • EINECS:
  • MDL Number:MFCD08062299
  • Synonyms:COCHLIOQUINONE A;(3R)-9-[(1S,2R,3S)-2-Acetyloxy-1,3-dimethylpentyl]-1,2,3,4aβ,5,6,6a,12,12aβ,12b-decahydro-12β-hydroxy-3α-(1-hydroxy-1-methylethyl)-6aα,12bα-dimethylpyrano[3,2-a]xanthene-8,11-dione;Luteoleersin;Cochlioquinone;Pyrano[3,2-a]xanthene-8,11-dione, 9-[(1S,2R,3S)-2-(acetyloxy)-1,3-dimethylpentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-3-(1-hydroxy-1-methylethyl)-6a,12b-dimethyl-, (3R,4aR,6aR,12S,12aS,12bR)-;Coclioquinone A;(2S,3R,4S)-2-[(3R,4aR,6aR,12S,12bR)-12-hydroxy-3-(2-hydroxypropan-2-yl)-6a,12b-dimethyl-8,11-dioxo-1,2,3,4a,5,6,12,12a-octahydropyrano[3,2-a]xanthen-9-yl]-4-methylhexan-3-yl] acetate
Price5 Properties Safety Information Description
5 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • TRC
Package
  • 500μg
  • 2.5mg
  • 5MG
  • ManufacturerAK Scientific
  • Product number1051CB
  • Product descriptionCochlioquinoneA
  • Packaging2.5mg
  • Price$1390
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberMTB0000899
  • Product descriptionCOCHLIOQUINONE-A 95.00%
  • Packaging5MG
  • Price$497.63
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19440
  • Product descriptionCochlioquinone A ≥99%
  • Packaging500μg
  • Price$291
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19440
  • Product descriptionCochlioquinone A ≥99%
  • Packaging2.5mg
  • Price$1160
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberC633560
  • Product descriptionCochlioquinoneA
  • Packaging500μg
  • Price$245
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1051CB CochlioquinoneA 2.5mg $1390 2021-12-16 Buy
American Custom Chemicals Corporation MTB0000899 COCHLIOQUINONE-A 95.00% 5MG $497.63 2021-12-16 Buy
Cayman Chemical 19440 Cochlioquinone A ≥99% 500μg $291 2024-03-01 Buy
Cayman Chemical 19440 Cochlioquinone A ≥99% 2.5mg $1160 2024-03-01 Buy
TRC C633560 CochlioquinoneA 500μg $245 2021-12-16 Buy

Properties

Melting point :135 °C
Boiling point :638.8±55.0 °C(Predicted)
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form :A yellow lyophilisate
pka :11.57±0.70(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Cochlioquinone A, a bioactive compound isolated from D. sacchari and Bipolaris sp., is an inhibitor of diacylglycerol kinase (DGK; Ki = 3.1 μM) and diacylglycerol acyltransferase (DGAT; IC50 = 5.6 μM). It has been shown to reduce the concentration of phosphatidic acid in T cell lymphoma with an IC50 value of 3 μM. It is also reported to compete with macrophage inflammatory protein-1α for binding to human CCR5 chemokine receptors with an IC50 value of 11 μM.

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Suppliers and manufacturers

BOC Sciences
Aladdin Scientific Lynnchem Novachemistry Shanghai Hongye Biotechnology Co. Ltd Shenzhen Polymeri Biochemical Technology Co., Ltd. Meng Cheng Technology (Shanghai) Co., LTD Zhejiang Huida Biotech Co., LTD MedBioPharmaceutical Technology Inc Zhejiang Huida Biotech Co., LTD