EAI-045
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- $7 - $1575
- Product name: EAI-045
- CAS: 1942114-09-1
- MF: C19H14FN3O3S
- MW: 383.4
- EINECS:-0
- MDL Number:MFCD30187871
- Synonyms:EAI-045;2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide;EA1045;α-(5-fluoro-2-hydroxyphenyl)-1,3-dihydro-1-oxo-N-2-thiazolyl-2H-Isoindole-2-acetamide;EAI 045;EAI-045;CS-2350;EAI045;EAI 045;EAI-045;N-(3-((5-fluoroethoxy)phenyl)amino)pyrimidin-4-yl)amino)phenyl)acrylamide (EAI-045)
28 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- AvaChem
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- ManufacturerAK Scientific
- Product number5125EG
- Product descriptionCID121231412
- Packaging10mg
- Price$185
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105328
- Product description2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97%
- Packaging5mg
- Price$7
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105328
- Product description2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97%
- Packaging10mg
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105328
- Product description2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97%
- Packaging25mg
- Price$14
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105328
- Product description2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97%
- Packaging50mg
- Price$20
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105328
- Product description2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97%
- Packaging100mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105328
- Product description2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97%
- Packaging250mg
- Price$44
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105328
- Product description2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97%
- Packaging1g
- Price$109
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105328
- Product description2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97%
- Packaging5g
- Price$376
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004748
- Product descriptionALPHA-(5-FLUORO-2-HYDROXYPHENYL)-1,3-DIHYDRO-1-OXO-N-2-THIAZOLYL-2H-ISOINDOLE-2-ACETAMIDE 95.00%
- Packaging5MG
- Price$505.05
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6054
- Product descriptionEAI045
- Packaging10mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6054
- Product descriptionEAI045
- Packaging25mg
- Price$330
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6054
- Product descriptionEAI045
- Packaging100mg
- Price$980
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3368
- Product descriptionEAI450
- Packaging5mg
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3368
- Product descriptionEAI450
- Packaging25mg
- Price$275
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3368
- Product descriptionEAI450
- Packaging100mg
- Price$575
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 5125EG | CID121231412 | 10mg | $185 | 2021-12-16 | Buy |
Ambeed | A105328 | 2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97% | 5mg | $7 | 2021-12-16 | Buy |
Ambeed | A105328 | 2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97% | 10mg | $10 | 2021-12-16 | Buy |
Ambeed | A105328 | 2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97% | 25mg | $14 | 2021-12-16 | Buy |
Ambeed | A105328 | 2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97% | 50mg | $20 | 2021-12-16 | Buy |
Ambeed | A105328 | 2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97% | 100mg | $30 | 2021-12-16 | Buy |
Ambeed | A105328 | 2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97% | 250mg | $44 | 2021-12-16 | Buy |
Ambeed | A105328 | 2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97% | 1g | $109 | 2021-12-16 | Buy |
Ambeed | A105328 | 2-(5-Fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide 97% | 5g | $376 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0004748 | ALPHA-(5-FLUORO-2-HYDROXYPHENYL)-1,3-DIHYDRO-1-OXO-N-2-THIAZOLYL-2H-ISOINDOLE-2-ACETAMIDE 95.00% | 5MG | $505.05 | 2021-12-16 | Buy |
ApexBio Technology | B6054 | EAI045 | 10mg | $200 | 2021-12-16 | Buy |
ApexBio Technology | B6054 | EAI045 | 25mg | $330 | 2021-12-16 | Buy |
ApexBio Technology | B6054 | EAI045 | 100mg | $980 | 2021-12-16 | Buy |
AvaChem | 3368 | EAI450 | 5mg | $105 | 2021-12-16 | Buy |
AvaChem | 3368 | EAI450 | 25mg | $275 | 2021-12-16 | Buy |
AvaChem | 3368 | EAI450 | 100mg | $575 | 2021-12-16 | Buy |
Properties
Density :1.546±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :≥38.3 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
pka :7.20±0.50(Predicted)
color :White to khaki
storage temp. :2-8°C
solubility :≥38.3 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
pka :7.20±0.50(Predicted)
color :White to khaki
Safety Information
Symbol(GHS): |
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Description
EAI045 is a potent and selective EGFR inhibitor (fourth generation). EAI045 targets selected drug-resistant EGFR mutants without affecting the wild-type receptor. EAI045 inhibits L858R/T790M-mutant EGFR with low-nanomolar potency in biochemical assays. Therefore, it is a potential candidate drug for the treatment of related non-small cell lung cancer (NSCLC). It should be noted that EAI-045 is effectively in targeting the EGFR C797S mutation, which is resistance to the third-generation EGFR inhibitors including AZD9291 (osimertinib) and CO-1686 (rociletinib).More related product prices
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