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ChemicalBook >> CAS DataBase List >> Ebastine

Ebastine

Ebastine price.
  • $35 - $1593.9
  • Product name: Ebastine
  • CAS: 90729-43-4
  • MF: C32H39NO2
  • MW: 469.66
  • EINECS:635-609-6
  • MDL Number:MFCD00865661
  • Synonyms:4'-(1,1-Dimethylethyl)-γ-[4-(diphenylmethoxy)piperidin-1-yl]butyrophenone;4'-tert-Butyl-γ-[4-(diphenylmethoxy)piperidino]butyrophenone;Ebastel-OD;LAS-90;IMp. A (EP): DiphenylMethanol (Benzhydrol);Ebastine Impurity;1-butanone,1-(4-(1,1-dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidiny ;4’-tert-butyl-4-(4-(diphenylmethoxy)piperidino)butyrophenone
29 prices
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Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • Arctom
  • AvaChem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 5mg
  • 10MG
  • 50mg
  • 0.1g
  • 100MG
  • 250mg
  • 500mg
  • 1g
  • 5g
  • ManufacturerAHH
  • Product numberAPI-1818
  • Product descriptionEbastine 98%
  • Packaging0.1g
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ51592
  • Product descriptionEbastine
  • Packaging500mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ51592
  • Product descriptionEbastine
  • Packaging1g
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63088
  • Product descriptionEbastine
  • Packaging1g
  • Price$146.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63088
  • Product descriptionEbastine
  • Packaging5g
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002511
  • Product descriptionEBASTINE 95.00%
  • Packaging10MG
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002511
  • Product descriptionEBASTINE 95.00%
  • Packaging100MG
  • Price$1593.9
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS441227
  • Product descriptionEbastine ≥98%
  • Packaging250mg
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS441227
  • Product descriptionEbastine ≥98%
  • Packaging1g
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS441227
  • Product descriptionEbastine ≥98%
  • Packaging5g
  • Price$279
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3632
  • Product descriptionEbastine
  • Packaging100mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3632
  • Product descriptionEbastine
  • Packaging1g
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBE164400
  • Product descriptionEbastine
  • Packaging100mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15372
  • Product descriptionEbastine ≥98%
  • Packaging500mg
  • Price$61
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15372
  • Product descriptionEbastine ≥98%
  • Packaging1g
  • Price$101
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15372
  • Product descriptionEbastine ≥98%
  • Packaging5g
  • Price$322
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1818 Ebastine 98% 0.1g $420 2021-12-16 Buy
AK Scientific J51592 Ebastine 500mg $60 2021-12-16 Buy
AK Scientific J51592 Ebastine 1g $84 2021-12-16 Buy
Alfa Aesar J63088 Ebastine 1g $146.65 2024-03-01 Buy
Alfa Aesar J63088 Ebastine 5g $480 2021-12-16 Buy
American Custom Chemicals Corporation API0002511 EBASTINE 95.00% 10MG $704.55 2021-12-16 Buy
American Custom Chemicals Corporation API0002511 EBASTINE 95.00% 100MG $1593.9 2021-12-16 Buy
Arctom AS441227 Ebastine ≥98% 250mg $69 2021-12-16 Buy
Arctom AS441227 Ebastine ≥98% 1g $133 2021-12-16 Buy
Arctom AS441227 Ebastine ≥98% 5g $279 2021-12-16 Buy
AvaChem 3632 Ebastine 100mg $35 2021-12-16 Buy
AvaChem 3632 Ebastine 1g $69 2021-12-16 Buy
Biosynth Carbosynth BE164400 Ebastine 100mg $50 2021-12-16 Buy
Cayman Chemical 15372 Ebastine ≥98% 500mg $61 2024-03-01 Buy
Cayman Chemical 15372 Ebastine ≥98% 1g $101 2024-03-01 Buy
Cayman Chemical 15372 Ebastine ≥98% 5g $322 2024-03-01 Buy

Properties

Melting point :80-82°C
Boiling point :596.3±50.0 °C(Predicted)
Density :1.09±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Slightly soluble in chloroform, methanol.
form :solid
pka :8.19±0.10(Predicted)
color :white
Merck :14,3484
CAS DataBase Reference :90729-43-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
Precautionary statements:
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P403 Store in a well-ventilated place.

Description

Ebastine belongs to an effective second generation histamine H1 receptor antagonist. One important property of it is that it doesn’t penetrate the blood brain barrier. Therefore, it is capable of blocking the H1 receptor in peripheral tissue without having some specific side effects such as sedation and drowsiness. Ebastine is mainly applied for the treatment of allergic rhinitis, pruritus as well as acting as an alternative drug in Decongestant. Upon entering into the human body, it can subject to the action of hepatic cytochrome P450 3A4 to be converted to an active carboxylic acid metabolite, carebastine. The later one is the major active form in vivo. Under certain range, it can inhibit T cell proliferation and the production of Th2-type pro-inflammatory cytokines through macrophages. Ebastine generally has a high safety property without causing cognitive/psychomotor impairment and sedation, like placebo. However, it can cause side effects such as inflammation of the air-cavities around nose, sore throat, indigestion, nausea, headache, and abdominal pain.

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