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ChemicalBook >> CAS DataBase List >> Edoxaban-d6

Edoxaban-d6

Edoxaban-d6 price.
  • $396 - $1850
  • Product name: Edoxaban-d6
  • CAS: 1304701-57-2
  • MF: C24H30ClN7O4S
  • MW: 548.06
  • EINECS:
  • MDL Number:MFCD32661438
  • Synonyms:Edoxaban-d6;N-[(1S,2R,4S)-4-[bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide;[2H6]-Edoxaban;Edoxaban hydrochloride salt;2H6]-Edoxaban hydrochloride salt
Price6 Properties Safety Information Description
6 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • Cayman Chemical
  • TRC
  • Usbiological
Package
  • 500ug
  • 500μg
  • 1mg
  • 5mg
  • Manufactureraablocks
  • Product numberAA01E0QG
  • Product descriptionEdoxaban-d6 ≥99%deuteratedforms(d1-d6)
  • Packaging1mg
  • Price$782
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4287DK
  • Product descriptionN-[(1S,2R,4S)-4-[Bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide
  • Packaging1mg
  • Price$889
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number25760
  • Product descriptionEdoxaban-d6 ≥99% deuterated forms (d1-d6)
  • Packaging500μg
  • Price$396
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25760
  • Product descriptionEdoxaban-d6 ≥99% deuterated forms (d1-d6)
  • Packaging1mg
  • Price$711
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberE555522
  • Product descriptionEdoxaban-d6
  • Packaging5mg
  • Price$1850
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number448076
  • Product descriptionEdoxaban-d6
  • Packaging500ug
  • Price$531
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01E0QG Edoxaban-d6 ≥99%deuteratedforms(d1-d6) 1mg $782 2021-12-16 Buy
AK Scientific 4287DK N-[(1S,2R,4S)-4-[Bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide 1mg $889 2021-12-16 Buy
Cayman Chemical 25760 Edoxaban-d6 ≥99% deuterated forms (d1-d6) 500μg $396 2024-03-01 Buy
Cayman Chemical 25760 Edoxaban-d6 ≥99% deuterated forms (d1-d6) 1mg $711 2024-03-01 Buy
TRC E555522 Edoxaban-d6 5mg $1850 2021-12-16 Buy
Usbiological 448076 Edoxaban-d6 500ug $531 2021-12-16 Buy

Properties

Melting point :>205°C (dec.)
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :Chloroform (Slightly), Dichloromethane (Slightly)
form :Solid
color :Pale Orange to Pale Red
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

Edoxaban-d6 is intended for use as an internal standard for the quantification of edoxaban by GC- or LC-MS. Edoxaban is an orally bioavailable and potent inhibitor of factor Xa (Kis = 0.561 and 0.903 nM for free and complexed human factor Xa, respectively). It is >10,000-fold selective for factor Xa over thrombin, FVIIa/sTF, FXIa, tPA, aPC, trypsin, plasmin, and chymotrypsin. Edoxaban prolongs prothrombin, activated partial thromboplastin, and thrombin clotting times in a concentration-dependent manner ex vivo in human plasma. Oral administration of edoxaban (0.5-12.5 mg/kg) reduces thrombus formation and prolongs prothrombin time in a dose-dependent manner in rat and rabbit models of venous stasis thrombosis. It also reduces thrombus formation in a rat model of platinum wire-induced venous thrombosis. Formulations containing edoxaban have been used to prevent stroke in patients with atrial fibrillation.

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Suppliers and manufacturers

Daicel Chiral Technologies (China)CO.,LTD Clearsynth Canada Inc. Shanghai Han-Xiang Chemical Co., Ltd. Shenzhen Popeye Biotechnology Co. Ltd. Jinan blalong chemical co. LTD ChemeGen(Shanghai) Biotechnology Co.,Ltd. Shenzhen ruikai de biotechnology co., ltd. Energy Chemical Manhag Testing Technology Co., Ltd Cato Research Chemicals Inc.