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ChemicalBook >> CAS DataBase List >> Etifoxine

Etifoxine

Etifoxine price.
  • $55 - $3176.25
  • Product name: Etifoxine
  • CAS: 21715-46-8
  • MF: C17H17ClN2O
  • MW: 300.78
  • EINECS:630-330-6
  • MDL Number:MFCD00868190
  • Synonyms:etafenoxine;36-801;6-Chloro-2-ethylamino-4-methyl-4-phenyl-4H-3,1-benzoxazine;Etifoxin;HOE-36801;HOE-36-801;2-Ethylamino-6-chloro-4-methyl-4-phenyl-4H-3,1-benzoxazine;Etifoxine
12 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • ChemScene
  • Crysdot
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number3658AH
  • Product descriptionEtifoxine
  • Packaging10mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010405
  • Product descriptionETIFOXINE 95.00%
  • Packaging10MG
  • Price$3176.25
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15999
  • Product descriptionEtifoxine ≥98%
  • Packaging5mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15999
  • Product descriptionEtifoxine ≥98%
  • Packaging10mg
  • Price$129
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15999
  • Product descriptionEtifoxine ≥98%
  • Packaging25mg
  • Price$296
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15999
  • Product descriptionEtifoxine ≥98%
  • Packaging50mg
  • Price$546
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1104
  • Product descriptionEtifoxine 99.87%
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1104
  • Product descriptionEtifoxine 99.87%
  • Packaging10mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1104
  • Product descriptionEtifoxine 99.87%
  • Packaging50mg
  • Price$340
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1104
  • Product descriptionEtifoxine 99.87%
  • Packaging100mg
  • Price$610
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002660
  • Product descriptionEtifoxine 98+%
  • Packaging10mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002660
  • Product descriptionEtifoxine 98+%
  • Packaging50mg
  • Price$221
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3658AH Etifoxine 10mg $240 2021-12-16 Buy
American Custom Chemicals Corporation API0010405 ETIFOXINE 95.00% 10MG $3176.25 2021-12-16 Buy
Cayman Chemical 15999 Etifoxine ≥98% 5mg $86 2024-03-01 Buy
Cayman Chemical 15999 Etifoxine ≥98% 10mg $129 2024-03-01 Buy
Cayman Chemical 15999 Etifoxine ≥98% 25mg $296 2024-03-01 Buy
Cayman Chemical 15999 Etifoxine ≥98% 50mg $546 2024-03-01 Buy
ChemScene CS-1104 Etifoxine 99.87% 5mg $70 2021-12-16 Buy
ChemScene CS-1104 Etifoxine 99.87% 10mg $100 2021-12-16 Buy
ChemScene CS-1104 Etifoxine 99.87% 50mg $340 2021-12-16 Buy
ChemScene CS-1104 Etifoxine 99.87% 100mg $610 2021-12-16 Buy
Crysdot CD31002660 Etifoxine 98+% 10mg $55 2021-12-16 Buy
Crysdot CD31002660 Etifoxine 98+% 50mg $221 2021-12-16 Buy

Properties

Melting point :90-92℃
Boiling point :421.2±55.0 °C(Predicted)
Density :1.1716 (rough estimate)
vapor pressure :0-1Pa at 20-25℃
refractive index :1.5800 (estimate)
storage temp. :Store at -20°C
solubility :DMSO:60.0(Max Conc. mg/mL);199.47(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);99.74(Max Conc. mM)
DMF:PBS (pH 7.2) (1:8):0.1(Max Conc. mg/mL);0.33(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);66.49(Max Conc. mM) form :Solid:particulate/powder
pka :4.89±0.40(Predicted)
color :Light yellow to yellow
LogP :4.09-4.52 at 21-25℃ and pH7

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H401 Toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 2 P273, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Etifoxine is a positive allosteric modulator of GABAA receptors that produces anxiolytic effects by preferentially modulating GABAA receptors containing β2 or β3 subunits (EC50s = 7.5 μM) over those bearing a β1 subunit (EC50 > 20 μM). It has also been identified as a ligand of the translocator protein, reportedly reducing inflammatory macrophage activation after peripheral nerve injury (20 μM) and promoting conditions favorable for axon regrowth.

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