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ChemicalBook >> CAS DataBase List >> Foretinib (GSK1363089)

Foretinib (GSK1363089)

Foretinib (GSK1363089) price.
  • $32 - $9455
  • Product name: Foretinib (GSK1363089)
  • CAS: 849217-64-7
  • MF: C34H34F2N4O6
  • MW: 632.65
  • EINECS:
  • MDL Number:MFCD22379992
  • Synonyms:GSK 1363089;N-[3-Fluoro-4-[[6-(methyloxy)-7-[[3-(morpholin-4-yl)propyl]oxy]quinolin-4-yl]oxy]phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;N-[3-Fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide;XL-880,Foretinib;XL880(GSK1363089);FORETINIB GLAXOSMITHKLINE PAPILLARY RENAL CELL CARCINOMA PHASE IIRSCH. TRIANGLE PARK, NC (SEE ALSO HEAD/NECK) (888) 825-5249;foretinib N1-{3-fluoro-4-[(6-(Methyloxy)-7-{[3-(4-Morpholinyl)propyl]oxy}-4-quinolinyl)oxy]phenyl}-N1'-(4-fluorophenyl)-1,1-cyclopropanedicarboxaMide;Foretinib (GSK1363089, XL880)
Price40 Properties Safety Information Description
40 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Tocris
  • TRC
Package
  • 5MG
  • 10
  • 1MG
  • 10mg
  • 20mg
  • 25mg
  • 50
  • 100mg
  • 10mM(in 1mL DMSO)
  • 50mg
  • 200mg
  • 250mg
  • 500mg
  • 1000mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1129-M010
  • Product descriptionForetinib ≥95%
  • Packaging10mg
  • Price$313
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1129-M050
  • Product descriptionForetinib ≥95%
  • Packaging50mg
  • Price$918
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1129
  • Product descriptionForetinib
  • Packaging10mg
  • Price$310
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010069
  • Product descriptionFORETINIB 95.00%
  • Packaging1MG
  • Price$235.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010069
  • Product descriptionFORETINIB 95.00%
  • Packaging5MG
  • Price$502.08
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2974
  • Product descriptionForetinib(GSK1363089)
  • Packaging10mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2974
  • Product descriptionForetinib(GSK1363089)
  • Packaging10mM(in 1mL DMSO)
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2974
  • Product descriptionForetinib(GSK1363089)
  • Packaging50mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2974
  • Product descriptionForetinib(GSK1363089)
  • Packaging100mg
  • Price$365
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60215
  • Product descriptionForetinib(GSK1363089) ≥98%
  • Packaging20mg
  • Price$288
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb153614
  • Product descriptionForetinib, Free Base >99% pure
  • Packaging5mg
  • Price$294.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb153614
  • Product descriptionForetinib, Free Base >99% pure
  • Packaging10mg
  • Price$333.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb153614
  • Product descriptionForetinib, Free Base >99% pure
  • Packaging25mg
  • Price$351.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb153614
  • Product descriptionForetinib, Free Base >99% pure
  • Packaging50mg
  • Price$487.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181181
  • Product descriptionForetinib (GSK1363089,XL880) >98%
  • Packaging100mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181181
  • Product descriptionForetinib (GSK1363089,XL880) >98%
  • Packaging250mg
  • Price$1283.5
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1129-M010 Foretinib ≥95% 10mg $313 2021-12-16 Buy
Adipogen Life Sciences SYN-1129-M050 Foretinib ≥95% 50mg $918 2021-12-16 Buy
AK Scientific SYN1129 Foretinib 10mg $310 2021-12-16 Buy
American Custom Chemicals Corporation API0010069 FORETINIB 95.00% 1MG $235.2 2021-12-16 Buy
American Custom Chemicals Corporation API0010069 FORETINIB 95.00% 5MG $502.08 2021-12-16 Buy
ApexBio Technology A2974 Foretinib(GSK1363089) 10mg $60 2021-12-16 Buy
ApexBio Technology A2974 Foretinib(GSK1363089) 10mM(in 1mL DMSO) $66 2021-12-16 Buy
ApexBio Technology A2974 Foretinib(GSK1363089) 50mg $220 2021-12-16 Buy
ApexBio Technology A2974 Foretinib(GSK1363089) 100mg $365 2021-12-16 Buy
Arctom CFN60215 Foretinib(GSK1363089) ≥98% 20mg $288 2021-12-16 Buy
Biorbyt Ltd orb153614 Foretinib, Free Base >99% pure 5mg $294.1 2021-12-16 Buy
Biorbyt Ltd orb153614 Foretinib, Free Base >99% pure 10mg $333.2 2021-12-16 Buy
Biorbyt Ltd orb153614 Foretinib, Free Base >99% pure 25mg $351.9 2021-12-16 Buy
Biorbyt Ltd orb153614 Foretinib, Free Base >99% pure 50mg $487.9 2021-12-16 Buy
Biorbyt Ltd orb181181 Foretinib (GSK1363089,XL880) >98% 100mg $690.2 2021-12-16 Buy
Biorbyt Ltd orb181181 Foretinib (GSK1363089,XL880) >98% 250mg $1283.5 2021-12-16 Buy
Next Last

Properties

Melting point :>98°C (dec.)
Boiling point :828.5±65.0 °C(Predicted)
Density :1.372
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO (Slightly), Ethanol (Slightly)
pka :13.14±0.70(Predicted)
form :Yellow powder.
color :Pale Yellow to Yellow
CAS DataBase Reference :849217-64-7

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P314 Get medical advice/attention if you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Foretinib (GSK1363089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met and KDR with IC50 of 0.4 nM and 0.9 nM in cell-free assays. Less potent against Ron, Flt-1/3/4, Kit, PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR. Phase 2.

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