GF109203X
- $28 - $4335
- Product name: GF109203X
- CAS: 133052-90-1
- MF: C25H24N4O2
- MW: 412.48
- EINECS:
- MDL Number:MFCD00236428
- Synonyms:Bisindolylmaleimide I (GF 109203X);InSolution? Bisindolylmaleimide I ;GO 6850;GO 6850 HCL;GF 109203X;GF-109203X HCL;GF109203X HYDROCHLORIDE;BISINDOLYLMALEIMIDE
50 prices
Selected condition:
Brand
- Adipogen Life Sciences
- AK Scientific
- Alfa Aesar
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
Package
- 250μg
- 2.5mg
- 10mg
- 250mg
- 1ml
- 1000mg
- 1
- 10
- 1mg
- 1unit
- 5mg
- 25mg
- 50mg
- 1g
- 10mM(in 1mL DMSO)
- 100mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0009-M001
- Product descriptionBisindolylmaleimide I ≥97%(NMR)
- Packaging1mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1641AH
- Product descriptionBisindolylmaleimide I
- Packaging1mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ63401
- Product descriptionBisindolylmaleimide 1
- Packaging5mg
- Price$153.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ63401
- Product descriptionBisindolylmaleimide 1
- Packaging25mg
- Price$421.65
- Updated2024-03-01
- Buy
- ManufacturerAmbeed
- Product numberA439059
- Product descriptionBisindolylmaleimide I 98+%
- Packaging5mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA439059
- Product descriptionBisindolylmaleimide I 98+%
- Packaging25mg
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA439059
- Product descriptionBisindolylmaleimide I 98+%
- Packaging50mg
- Price$340
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA439059
- Product descriptionBisindolylmaleimide I 98+%
- Packaging100mg
- Price$510
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA439059
- Product descriptionBisindolylmaleimide I 98+%
- Packaging1g
- Price$4335
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000052
- Product descriptionBISINDOLYLMALEIMIDE (I) 95.00%
- Packaging1MG
- Price$708.48
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000052
- Product descriptionBISINDOLYLMALEIMIDE (I) 95.00%
- Packaging5MG
- Price$986.15
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8342
- Product descriptionGF 109203X
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8342
- Product descriptionGF 109203X
- Packaging5mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8342
- Product descriptionGF 109203X
- Packaging10mM(in 1mL DMSO)
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8342
- Product descriptionGF 109203X
- Packaging10mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60111
- Product descriptionBisindolylmaleimideI(GF109203X)
- Packaging10mg
- Price$288
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | AG-CR1-0009-M001 | Bisindolylmaleimide I ≥97%(NMR) | 1mg | $55 | 2021-12-16 | Buy |
AK Scientific | 1641AH | Bisindolylmaleimide I | 1mg | $100 | 2021-12-16 | Buy |
Alfa Aesar | J63401 | Bisindolylmaleimide 1 | 5mg | $153.65 | 2024-03-01 | Buy |
Alfa Aesar | J63401 | Bisindolylmaleimide 1 | 25mg | $421.65 | 2024-03-01 | Buy |
Ambeed | A439059 | Bisindolylmaleimide I 98+% | 5mg | $96 | 2021-12-16 | Buy |
Ambeed | A439059 | Bisindolylmaleimide I 98+% | 25mg | $230 | 2021-12-16 | Buy |
Ambeed | A439059 | Bisindolylmaleimide I 98+% | 50mg | $340 | 2021-12-16 | Buy |
Ambeed | A439059 | Bisindolylmaleimide I 98+% | 100mg | $510 | 2021-12-16 | Buy |
Ambeed | A439059 | Bisindolylmaleimide I 98+% | 1g | $4335 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000052 | BISINDOLYLMALEIMIDE (I) 95.00% | 1MG | $708.48 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | KIN0000052 | BISINDOLYLMALEIMIDE (I) 95.00% | 5MG | $986.15 | 2021-12-16 | Buy |
ApexBio Technology | A8342 | GF 109203X | 1unit | $28 | 2021-12-16 | Buy |
ApexBio Technology | A8342 | GF 109203X | 5mg | $60 | 2021-12-16 | Buy |
ApexBio Technology | A8342 | GF 109203X | 10mM(in 1mL DMSO) | $100 | 2021-12-16 | Buy |
ApexBio Technology | A8342 | GF 109203X | 10mg | $120 | 2021-12-16 | Buy |
Arctom | CFN60111 | BisindolylmaleimideI(GF109203X) | 10mg | $288 | 2021-12-16 | Buy |
Properties
Melting point :280℃ (decomposition)
Boiling point :685.6±55.0 °C(Predicted)
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ~1 mg/mlsoluble
form :Liquid
pka :8.13±0.60(Predicted)
color :Orange
Water Solubility :Insoluble in water.
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 6 months.
Boiling point :685.6±55.0 °C(Predicted)
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ~1 mg/mlsoluble
form :Liquid
pka :8.13±0.60(Predicted)
color :Orange
Water Solubility :Insoluble in water.
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 6 months.
Safety Information
Symbol(GHS): | |||||||||||||||
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Signal word: | Danger | ||||||||||||||
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Description
Bisindolylmaleimide I (BIM I) is a highly selective, cell-permeable, and reversible protein kinase C (PKC) inhibitor (Ki = 14 nM) that is structurally similar to the poorly selective PKC inhibitor staurosporine. It acts as a competitive inhibitor for the ATP binding site of PKC and shows high selectivity for PKCα-, β1-, β2-, γ-, δ-, and ε-isozymes. BIM I directly inhibits GSK3 in primary adipocyte lysates (IC50 = 360 nM) and in GSK3β immunoprecipitates derived from rat epididymal adipocytes (IC50 = 170 nM). This compound also competitively antagonizes the 5-HT3 receptor with a Ki value of 61 nM.More related product prices
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Suppliers and manufacturers
Hangzhou FandaChem Co.,Ltd.
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Zhejiang J&C Biological Technology Co.,Limited