GSK 525762A
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- $32 - $9900
- Product name: GSK 525762A
- CAS: 1260907-17-2
- MF: C22H22ClN5O2
- MW: 423.9
- EINECS:
- MDL Number:MFCD30207861
- Synonyms:I-BET-762;GSK 525762A (I-BET-762);GSK525762 (I-BET-762);GSK525762;4H-[1,2,4]Triazolo[4,3-a][1,4]benzodiazepine-4-acetamide, 6-(4-chlorophenyl)-N-ethyl-8-methoxy-1-methyl-, (4S)-;(4S)-6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide GSK 525762A I-BET-762;GSK 525762A (4S)-6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide;IBET762(GSK525762A)
34 prices
Selected condition：
Brand
- Adipogen Life Sciences
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- BroadPharm
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 25
- 1mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1g
- 5g
- ManufacturerAdipogen Life Sciences
- Product numberSYN-3033-M100
- Product descriptionI-BET762 ≥95%
- Packaging100mg
- Price$778
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1498
- Product descriptionI-BET-762
- Packaging50mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60280
- Product descriptionMolibresib(I-BET-762) ≥98%
- Packaging10mg
- Price$288
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546202
- Product descriptionI-bET762 >98%
- Packaging5mg
- Price$190.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546202
- Product descriptionI-bET762 >98%
- Packaging25mg
- Price$547.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146271
- Product descriptionGSK525762A(I-BET762) >98%
- Packaging100mg
- Price$690.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146271
- Product descriptionGSK525762A(I-BET762) >98%
- Packaging250mg
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146271
- Product descriptionGSK525762A(I-BET762) >98%
- Packaging1g
- Price$2395.3
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFG137683
- Product descriptionI-BET 762
- Packaging10mg
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFG137683
- Product descriptionI-BET 762
- Packaging50mg
- Price$437.5
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-23442
- Product descriptionI-BET762 98%
- Packaging10mg
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10676
- Product descriptionI-BET762 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10676
- Product descriptionI-BET762 ≥98%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10676
- Product descriptionI-BET762 ≥98%
- Packaging10mg
- Price$199
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10676
- Product descriptionI-BET762 ≥98%
- Packaging25mg
- Price$456
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0717
- Product descriptionMolibresib 99.85%
- Packaging5mg
- Price$106
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-3033-M100 | I-BET762 ≥95% | 100mg | $778 | 2021-12-16 | Buy |
| ApexBio Technology | B1498 | I-BET-762 | 50mg | $450 | 2021-12-16 | Buy |
| Arctom | CFN60280 | Molibresib(I-BET-762) ≥98% | 10mg | $288 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546202 | I-bET762 >98% | 5mg | $190.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546202 | I-bET762 >98% | 25mg | $547.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146271 | GSK525762A(I-BET762) >98% | 100mg | $690.2 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146271 | GSK525762A(I-BET762) >98% | 250mg | $1208.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146271 | GSK525762A(I-BET762) >98% | 1g | $2395.3 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FG137683 | I-BET 762 | 10mg | $145 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FG137683 | I-BET 762 | 50mg | $437.5 | 2021-12-16 | Buy |
| BroadPharm | BP-23442 | I-BET762 98% | 10mg | $230 | 2021-12-16 | Buy |
| Cayman Chemical | 10676 | I-BET762 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 10676 | I-BET762 ≥98% | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 10676 | I-BET762 ≥98% | 10mg | $199 | 2024-03-01 | Buy |
| Cayman Chemical | 10676 | I-BET762 ≥98% | 25mg | $456 | 2024-03-01 | Buy |
| ChemScene | CS-0717 | Molibresib 99.85% | 5mg | $106 | 2021-12-16 | Buy |
Properties
Melting point :>132°C (dec.)
Density :1.35
storage temp. :2-8°C
solubility :Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)
pka :15.71±0.46(Predicted)
form :powder
color :white to beige
optical activity :[α]/D +80 to +90°, c = 0.3 in methanol
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Density :1.35
storage temp. :2-8°C
solubility :Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)
pka :15.71±0.46(Predicted)
form :powder
color :white to beige
optical activity :[α]/D +80 to +90°, c = 0.3 in methanol
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Safety Information
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Description
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, affect inflammatory gene expression by controlling the assembly of histone acetylation-dependent chromatin complexes. I-BET762 is a synthetic compound which interacts with BET proteins with high-affinity (Kd = 32.5-42.5 nM). It blocks binding of BET proteins with acetylated histones, disrupting the formation of chromatin complexes involved in the expression of specific inflammatory genes in activated macrophages. Through these actions, I-BET762 provides protection against bacteria-induced sepsis and lipopolysaccharide-triggered endotoxic shock.More related product prices
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