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ChemicalBook >> CAS DataBase List >> GSK872

GSK872

GSK872 price.
  • $32 - $764
  • Product name: GSK872
  • CAS: 1346546-69-7
  • MF: C19H17N3O2S2
  • MW: 383.49
  • EINECS:
  • MDL Number:MFCD30481302
  • Synonyms:GSK872;N-5-benzothiazolyl-6-[(1-methylethyl)sulfonyl]-4-Quinolinamine;N-(6-(Isopropylsulfonyl)quinolin-4-yl)benzo[d]thiazol-5-amine HCl salt;N-(6-(Isopropylsulfonyl)quinolin-4-yl)benzo[d]thiazol-5-amine HCL SALT // GSK-872 HCL;4-Quinolinamine, N-5-benzothiazolyl-6-[(1-methylethyl)sulfonyl]-;GSK'872 (GSK2399872A);GSK'872;GSK872;GSK2399872A;GSK2399872A
21 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
Package
  • 10
  • 1mg
  • 10mg
  • 50
  • 2mg
  • 5mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product numberSYN5481
  • Product descriptionGSK872
  • Packaging10mg
  • Price$217
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA306277
  • Product descriptionGSK'872 95%
  • Packaging5mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA306277
  • Product descriptionGSK'872 95%
  • Packaging10mg
  • Price$192
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA306277
  • Product descriptionGSK'872 95%
  • Packaging25mg
  • Price$325
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA306277
  • Product descriptionGSK'872 95%
  • Packaging100mg
  • Price$718
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon3024
  • Product descriptionGSK'872-GSK2399872A 98%
  • Packaging50mg
  • Price$368.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBG166846
  • Product descriptionGSK 872
  • Packaging10mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBG166846
  • Product descriptionGSK 872
  • Packaging50mg
  • Price$437.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number23300
  • Product descriptionGSK872 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23300
  • Product descriptionGSK872 ≥98%
  • Packaging5mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23300
  • Product descriptionGSK872 ≥98%
  • Packaging10mg
  • Price$214
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004935
  • Product descriptionGSK'872 95%
  • Packaging2mg
  • Price$47
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004935
  • Product descriptionGSK'872 95%
  • Packaging5mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004935
  • Product descriptionGSK'872 95%
  • Packaging10mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004935
  • Product descriptionGSK'872 95%
  • Packaging25mg
  • Price$257
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004935
  • Product descriptionGSK'872 95%
  • Packaging50mg
  • Price$491
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5481 GSK872 10mg $217 2021-12-16 Buy
Ambeed A306277 GSK'872 95% 5mg $138 2021-12-16 Buy
Ambeed A306277 GSK'872 95% 10mg $192 2021-12-16 Buy
Ambeed A306277 GSK'872 95% 25mg $325 2021-12-16 Buy
Ambeed A306277 GSK'872 95% 100mg $718 2021-12-16 Buy
Axon Medchem Axon3024 GSK'872-GSK2399872A 98% 50mg $368.5 2021-12-16 Buy
Biosynth Carbosynth BG166846 GSK 872 10mg $125 2021-12-16 Buy
Biosynth Carbosynth BG166846 GSK 872 50mg $437.5 2021-12-16 Buy
Cayman Chemical 23300 GSK872 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 23300 GSK872 ≥98% 5mg $116 2024-03-01 Buy
Cayman Chemical 23300 GSK872 ≥98% 10mg $214 2024-03-01 Buy
Crysdot CD31004935 GSK'872 95% 2mg $47 2021-12-16 Buy
Crysdot CD31004935 GSK'872 95% 5mg $85 2021-12-16 Buy
Crysdot CD31004935 GSK'872 95% 10mg $144 2021-12-16 Buy
Crysdot CD31004935 GSK'872 95% 25mg $257 2021-12-16 Buy
Crysdot CD31004935 GSK'872 95% 50mg $491 2021-12-16 Buy

Properties

Boiling point :625.7±55.0 °C(Predicted)
Density :1.395±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Room temperature
solubility :Soluble in DMSO (up to at least 25 mg/ml)
pka :5.53±0.49(Predicted)
form :solid
color :Off-White or pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

GSK 872 (CAS 1346546-69-7) is a potent (IC50 = 1.8nM domain binding; IC50 = 1.3 nM kinase activity) and selective inhibitor of receptor interacting protein 3 (RIP3).1 It is able to prevent necroptosis, virus-induced necrosis, and TLR3-induced necrosis.1,2 GSK872 can induce Caspase8-mediated apoptosis at higher concentrations (e.g.3 μM).2

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