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ChemicalBook >> CAS DataBase List >> GW-501516

GW-501516

GW-501516 price.
  • $30 - $1960
  • Product name: GW-501516
  • CAS: 317318-70-0
  • MF: C21H18F3NO3S2
  • MW: 453.5
  • EINECS:1592732-453-0
  • MDL Number:MFCD09033000
  • Synonyms:2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylsulfanyl]phenoxy]acetic acid;GW 501516, >=98%;ENDUROBOL (GW-501516)/CARDARINE/;Cardarine(GW501516, GSK-516);GW-501615;2-(4-((2-(4-(Trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methylthio)-2-methylphenoxy)acetic a;{2-Methyl-4-[4-Methyl-2-(4-trifluoroMethyl-phenyl)-thiazol-5-ylMethylsulfanyl]-phenoxy}-acetic acid;Aceticacid, [2-Methyl-4-[[[4-Methyl-2-[4-(trifluoroMethyl)phenyl]-5-thiazolyl]Methyl]thio]phenoxy]-(9CI)
44 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemcia Scientific
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 2.5MG
  • 10mg
  • 10mM(in 1mL DMSO)
  • 1mg
  • 5mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3641-M001
  • Product descriptionGW501516 ≥98%(NMR)
  • Packaging1mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3641-M025
  • Product descriptionGW501516 ≥98%(NMR)
  • Packaging25mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX5246
  • Product descriptionGW501516
  • Packaging5g
  • Price$334
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0049561
  • Product description2-(2-METHYL-4-((4-METHYL-2-(4-TRIFLUOROMETHYL)PHENYL)THIAZOL-5-YL)METHYLTHIO)PHENOXY)ACETIC ACID 95.00%
  • Packaging2.5MG
  • Price$682
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0049561
  • Product description2-(2-METHYL-4-((4-METHYL-2-(4-TRIFLUOROMETHYL)PHENYL)THIAZOL-5-YL)METHYLTHIO)PHENOXY)ACETIC ACID 95.00%
  • Packaging25MG
  • Price$1686.3
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4309
  • Product descriptionGW501516
  • Packaging100mg
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4309
  • Product descriptionGW501516
  • Packaging50mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4309
  • Product descriptionGW501516
  • Packaging10mg
  • Price$78
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4309
  • Product descriptionGW501516
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4309
  • Product descriptionGW501516
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146203
  • Product descriptionGW501516(GSK-516) >98%
  • Packaging100mg
  • Price$414.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146203
  • Product descriptionGW501516(GSK-516) >98%
  • Packaging250mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146203
  • Product descriptionGW501516(GSK-516) >98%
  • Packaging1g
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM23721
  • Product descriptionGW 501516
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM23721
  • Product descriptionGW 501516
  • Packaging50mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10004272
  • Product descriptionGW 501516 ≥98%
  • Packaging10mg
  • Price$151
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3641-M001 GW501516 ≥98%(NMR) 1mg $30 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3641-M025 GW501516 ≥98%(NMR) 25mg $280 2021-12-16 Buy
AK Scientific X5246 GW501516 5g $334 2021-12-16 Buy
American Custom Chemicals Corporation HCH0049561 2-(2-METHYL-4-((4-METHYL-2-(4-TRIFLUOROMETHYL)PHENYL)THIAZOL-5-YL)METHYLTHIO)PHENOXY)ACETIC ACID 95.00% 2.5MG $682 2021-12-16 Buy
American Custom Chemicals Corporation HCH0049561 2-(2-METHYL-4-((4-METHYL-2-(4-TRIFLUOROMETHYL)PHENYL)THIAZOL-5-YL)METHYLTHIO)PHENOXY)ACETIC ACID 95.00% 25MG $1686.3 2021-12-16 Buy
ApexBio Technology A4309 GW501516 100mg $260 2021-12-16 Buy
ApexBio Technology A4309 GW501516 50mg $190 2021-12-16 Buy
ApexBio Technology A4309 GW501516 10mg $78 2021-12-16 Buy
ApexBio Technology A4309 GW501516 10mM(in 1mL DMSO) $55 2021-12-16 Buy
ApexBio Technology A4309 GW501516 5mg $50 2021-12-16 Buy
Biorbyt Ltd orb146203 GW501516(GSK-516) >98% 100mg $414.8 2021-12-16 Buy
Biorbyt Ltd orb146203 GW501516(GSK-516) >98% 250mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb146203 GW501516(GSK-516) >98% 1g $1208.7 2021-12-16 Buy
Biosynth Carbosynth FM23721 GW 501516 10mg $75 2021-12-16 Buy
Biosynth Carbosynth FM23721 GW 501516 50mg $200 2021-12-16 Buy
Cayman Chemical 10004272 GW 501516 ≥98% 10mg $151 2024-03-01 Buy

Properties

Melting point :134-136°C
Boiling point :584.5±60.0 °C(Predicted)
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :3.17±0.10(Predicted)
color :white to beige
BRN :18515150
Stability :Light Sensitive
InChI :InChI=1S/C21H18F3NO3S2/c1-12-9-16(7-8-17(12)28-10-19(26)27)29-11-18-13(2)25-20(30-18)14-3-5-15(6-4-14)21(22,23)24/h3-9H,10-11H2,1-2H3,(H,26,27)
InChIKey :YDBLKRPLXZNVNB-UHFFFAOYSA-N
SMILES :C(O)(=O)COC1=CC=C(SCC2SC(C3=CC=C(C(F)(F)F)C=C3)=NC=2C)C=C1C
CAS DataBase Reference :317318-70-0

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

GW501516 is the most selective and potent PPARβ (EC50=1.1nM) agonist that has been demonstrated to be 1,000-fold more selective in comparison to existing subtypes. Studies demonstrate that GW501516 can regulate expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells. Additionally, GW501516 has been shown to block insulin resistance and fatty acid-induced nuclear factor-κB (NF-κB) activation.

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