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ChemicalBook >> CAS DataBase List >> H-8 DIHYDROCHLORIDE

H-8 DIHYDROCHLORIDE

H-8 DIHYDROCHLORIDE price.
  • $37 - $1265
  • Product name: H-8 DIHYDROCHLORIDE
  • CAS: 113276-94-1
  • MF: C12H17Cl2N3O2S
  • MW: 338.25
  • EINECS:
  • MDL Number:MFCD00036962
  • Synonyms:5-IsoquinolinesulfonaMide,N-[2-(MethylaMino)ethyl]-, hydrochloride (1:2);H-8 DIHYDROCHLORIDE;H-8 HYDROCHLORIDE;H-8;N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE 2HCL;N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE, DI-HCL SALT;N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE DIHYDROCHLORIDE;N-(2-[METHYLAMINO]ETHYL)-5-ISOQUINOLINESULFONAMIDE HYDROCHLORIDE
16 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5MG
  • 10mg
  • 25MG
  • 50mg
  • 250mg
  • 5g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-0001-M010
  • Product descriptionH-8 dihydrochloride ≥98%(NMR)
  • Packaging10mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-17360
  • Product descriptionN-[2-(Methylamino)ethyl]-5-isoquinolinesulfonamidedihydrochloride 98%
  • Packaging5g
  • Price$312
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1782AH
  • Product descriptionH-8 dihydrochloride
  • Packaging50mg
  • Price$316
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001336
  • Product descriptionH-8 DIHYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$498
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001336
  • Product descriptionH-8 DIHYDROCHLORIDE 95.00%
  • Packaging25MG
  • Price$720.74
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4683
  • Product descriptionH-8(hydrochloride)
  • Packaging50mg
  • Price$208
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010249
  • Product descriptionH-8 (hydrochloride) ≥98%
  • Packaging5mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010249
  • Product descriptionH-8 (hydrochloride) ≥98%
  • Packaging10mg
  • Price$59
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010249
  • Product descriptionH-8 (hydrochloride) ≥98%
  • Packaging25mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010249
  • Product descriptionH-8 (hydrochloride) ≥98%
  • Packaging50mg
  • Price$195
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM146095
  • Product descriptionN-(2-(methylamino)ethyl)isoquinoline-5-sulfonamidedihydrochloride 95%
  • Packaging250mg
  • Price$1193
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11348851
  • Product descriptionN-(2-(Methylamino)ethyl)isoquinoline-5-sulfonamidedihydrochloride 95+%
  • Packaging250mg
  • Price$1265
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberM9656
  • Product descriptionH-8 dihydrochloride >98% (HPLC)
  • Packaging5mg
  • Price$156
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number371958
  • Product descriptionH-8 dihydrochloride
  • Packaging1mg
  • Price$167
  • Updated2023-01-07
  • Buy
  • ManufacturerTRC
  • Product numberM286200
  • Product descriptionN-[2-(Methylamino)ethyl]-5-isoquinolinesulfonamideDihydrochloride
  • Packaging250mg
  • Price$810
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number044876
  • Product descriptionH-8 dihydrochloride
  • Packaging10mg
  • Price$282
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-0001-M010 H-8 dihydrochloride ≥98%(NMR) 10mg $40 2021-12-16 Buy
AHH MT-17360 N-[2-(Methylamino)ethyl]-5-isoquinolinesulfonamidedihydrochloride 98% 5g $312 2021-12-16 Buy
AK Scientific 1782AH H-8 dihydrochloride 50mg $316 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001336 H-8 DIHYDROCHLORIDE 95.00% 5MG $498 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001336 H-8 DIHYDROCHLORIDE 95.00% 25MG $720.74 2021-12-16 Buy
ApexBio Technology C4683 H-8(hydrochloride) 50mg $208 2021-12-16 Buy
Cayman Chemical 10010249 H-8 (hydrochloride) ≥98% 5mg $37 2024-03-01 Buy
Cayman Chemical 10010249 H-8 (hydrochloride) ≥98% 10mg $59 2024-03-01 Buy
Cayman Chemical 10010249 H-8 (hydrochloride) ≥98% 25mg $116 2024-03-01 Buy
Cayman Chemical 10010249 H-8 (hydrochloride) ≥98% 50mg $195 2024-03-01 Buy
Chemenu CM146095 N-(2-(methylamino)ethyl)isoquinoline-5-sulfonamidedihydrochloride 95% 250mg $1193 2021-12-16 Buy
Crysdot CD11348851 N-(2-(Methylamino)ethyl)isoquinoline-5-sulfonamidedihydrochloride 95+% 250mg $1265 2021-12-16 Buy
Sigma-Aldrich M9656 H-8 dihydrochloride >98% (HPLC) 5mg $156 2024-03-01 Buy
Sigma-Aldrich 371958 H-8 dihydrochloride 1mg $167 2023-01-07 Buy
TRC M286200 N-[2-(Methylamino)ethyl]-5-isoquinolinesulfonamideDihydrochloride 250mg $810 2021-12-16 Buy
Usbiological 044876 H-8 dihydrochloride 10mg $282 2021-12-16 Buy

Properties

Melting point :221-222℃ (methanol water )
storage temp. :2-8°C
solubility :ethanol: 25 mg/mL, clear, colorless
form :Lyophilized
color :White to Off-White
CAS DataBase Reference :113276-94-1(CAS DataBase Reference)

Safety Information

Symbol(GHS):
Signal word:
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Description

The H series isoquinolinesulfonamide protein kinase (PK) inhibitors are widely used to block signaling pathways to elucidate mechanisms of cellular regulation and signal transduction. H-8, an isoquinolinesulfonamide protein kinase (PK) inhibitor, is a potent inhibitor of PKA and PKG and shows moderate inhibition for PKC and MLCK with Ki values of 1.2, 0.48, 15, and 68 μM, respectively. H-8 can disrupt transcriptional elongation by inhibiting cyclin C/Cdk8 and cyclin H/Cdk7/p36 CTD kinase activity with IC50 values of 47 and 6.2 μM, respectively.