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ChemicalBook >> CAS DataBase List >> Indinavir

Indinavir

Indinavir price.
  • $104 - $4725
  • Product name: Indinavir
  • CAS: 150378-17-9
  • MF: C36H47N5O4
  • MW: 613.79
  • EINECS:
  • MDL Number:MFCD00866938
  • Synonyms:INDINAVIR;Indinavir&Int.;(1(1S,2R)5(S))-2,3,5-TRIDEOXY-N-(2,3-DIHYDRO-2HYDROXY-1H-INDEN-1-YI)-;(1(1S,2R),5(S))-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-D-erythro-pentonamide;[I(1S,2R),5(S)]-2,3,5-Trideoxy-N-(2,3.Dihydro-2-hydrox-Lh-inden-1-y1)-5-[2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-D-erythro-pentonamide;L-735524;MK-639:Cfixivan;Indinavir(MK-639
15 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • AvaChem
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
  • 1MG
  • 10MG
  • 0.01g
  • 25mg
  • 100mg
  • 1g
  • ManufacturerAHH
  • Product numberAPI-1193
  • Product descriptionIndinavir 98%
  • Packaging0.01g
  • Price$565
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberE104
  • Product descriptionIndinavir
  • Packaging25mg
  • Price$262.48
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberE104
  • Product descriptionIndinavir
  • Packaging100mg
  • Price$786
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002994
  • Product descriptionINDINAVIR 95.00%
  • Packaging1MG
  • Price$675.51
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002994
  • Product descriptionINDINAVIR 95.00%
  • Packaging10MG
  • Price$1252.78
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2152B
  • Product descriptionIndinavir
  • Packaging10mg
  • Price$129
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2152B
  • Product descriptionIndinavir
  • Packaging100mg
  • Price$249
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2152B
  • Product descriptionIndinavir
  • Packaging1g
  • Price$490
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN11198
  • Product descriptionIndinavir
  • Packaging10mg
  • Price$104
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN11198
  • Product descriptionIndinavir
  • Packaging25mg
  • Price$243
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8906
  • Product descriptionIndinavir >98%
  • Packaging1g
  • Price$1400
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number099281
  • Product descriptionIndinavir 95+%
  • Packaging1g
  • Price$4725
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number51840
  • Product descriptionIndinavir
  • Packaging100mg
  • Price$1460
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberI525001
  • Product descriptionIndinavir
  • Packaging10mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number014803
  • Product descriptionIndinavir
  • Packaging10mg
  • Price$418
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1193 Indinavir 98% 0.01g $565 2021-12-16 Buy
AK Scientific E104 Indinavir 25mg $262.48 2021-12-16 Buy
AK Scientific E104 Indinavir 100mg $786 2021-12-16 Buy
American Custom Chemicals Corporation API0002994 INDINAVIR 95.00% 1MG $675.51 2021-12-16 Buy
American Custom Chemicals Corporation API0002994 INDINAVIR 95.00% 10MG $1252.78 2021-12-16 Buy
AvaChem 2152B Indinavir 10mg $129 2021-12-16 Buy
AvaChem 2152B Indinavir 100mg $249 2021-12-16 Buy
AvaChem 2152B Indinavir 1g $490 2021-12-16 Buy
CSNpharm CSN11198 Indinavir 10mg $104 2021-12-16 Buy
CSNpharm CSN11198 Indinavir 25mg $243 2021-12-16 Buy
DC Chemicals DC8906 Indinavir >98% 1g $1400 2021-12-16 Buy
Matrix Scientific 099281 Indinavir 95+% 1g $4725 2021-12-16 Buy
Medical Isotopes, Inc. 51840 Indinavir 100mg $1460 2021-12-16 Buy
TRC I525001 Indinavir 10mg $350 2021-12-16 Buy
Usbiological 014803 Indinavir 10mg $418 2021-12-16 Buy

Properties

Melting point :153-154°; mp 167.5-168°
alpha :D22 +24.1° (c = 0.0133 in chloroform)
Boiling point :877.9±65.0 °C(Predicted)
Density :1.25±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
pka :pKa 3.8/6.2(H2O,t undefined,Iundefined) (Uncertain)
Water Solubility :70mg/L(temperature not stated)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Crixivan was launched in Australia, Switzerland, the UK and the US as an orally-bioavailable HIV-1 protease inhibitor. The compound can be prepared by coupling an optically active piperazine derivative with an epoxide derivative (now commercially available). The synthesis of the proteins, reverse transcriptase, integrase, structural proteins and a protease, required by the virus to complete its lifecycle, can be interupted if the protease enzyme is not capable of cleaving a proform polypeptide chain into these components. lndinavir inhibits this process and is more potent than the first approved protease inhibitor saquinavir. This effect was noted by the increase in CD4+ cells and a decrease in HIV RNA levels. Since indinavir is metabolized by the CYP3A4 isozyme, care must be taken with patients with hepatic insufficiency and to sex-related differences in the level of this enzyme. Other than nephrolithiasis (5%), indinavir is relatively safe and well tolerated.

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