Infigratinib
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- $50 - $2250
- Product name: Infigratinib
- CAS: 872511-34-7
- MF: C26H31Cl2N7O3
- MW: 560.48
- EINECS:
- MDL Number:MFCD22123241
- Synonyms:3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea;BGJ 398;BGJ398 (NVP-BGJ398);NVP-BGJ398;3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea NVP-BGJ398;NVP-BGJ398 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea;Urea, N'-(2,6-dichloro-3,5-dimethoxyphenyl)-N-[6-[[4-(4-ethyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]-N-methyl-, methanesulfonate;Urea, N'-(2,6-dichloro-3,5-dimethoxyphenyl)-N-[6-[[4-(4-ethyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]-N-methyl-
35 prices
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Brand
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- TRC
Package
- 1mg
- 5mg
- 10MG
- 20mg
- 25mg
- 50MG
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 2g
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1152-M005
- Product descriptionNVP-BGJ398 ≥95%
- Packaging5mg
- Price$113
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN1152
- Product descriptionNVP-BGJ398
- Packaging100mg
- Price$555
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0045867
- Product descriptionBGJ-398 95.00%
- Packaging5MG
- Price$750.2
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0045867
- Product descriptionBGJ-398 95.00%
- Packaging10MG
- Price$802.73
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0045867
- Product descriptionBGJ-398 95.00%
- Packaging50MG
- Price$1328.25
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3014
- Product descriptionBGJ398
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60052
- Product descriptionInfigratinib(BGJ398) ≥98%
- Packaging20mg
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546258
- Product descriptionNVP-bGJ398 >98%
- Packaging10mg
- Price$181.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546258
- Product descriptionNVP-bGJ398 >98%
- Packaging50mg
- Price$397.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146290
- Product descriptionNVP-BGJ398(Infigratinib) >98%
- Packaging100mg
- Price$542.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146290
- Product descriptionNVP-BGJ398(Infigratinib) >98%
- Packaging250mg
- Price$986
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146290
- Product descriptionNVP-BGJ398(Infigratinib) >98%
- Packaging1g
- Price$1802
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD46729
- Product descriptionNVP BGJ 398
- Packaging10mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD46729
- Product descriptionNVP BGJ 398
- Packaging50mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19157
- Product descriptionBGJ398 ≥98%
- Packaging1mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19157
- Product descriptionBGJ398 ≥98%
- Packaging5mg
- Price$120
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-1152-M005 | NVP-BGJ398 ≥95% | 5mg | $113 | 2021-12-16 | Buy |
| AK Scientific | SYN1152 | NVP-BGJ398 | 100mg | $555 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0045867 | BGJ-398 95.00% | 5MG | $750.2 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0045867 | BGJ-398 95.00% | 10MG | $802.73 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0045867 | BGJ-398 95.00% | 50MG | $1328.25 | 2021-12-16 | Buy |
| ApexBio Technology | A3014 | BGJ398 | 5mg | $80 | 2021-12-16 | Buy |
| Arctom | CFN60052 | Infigratinib(BGJ398) ≥98% | 20mg | $208 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546258 | NVP-bGJ398 >98% | 10mg | $181.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546258 | NVP-bGJ398 >98% | 50mg | $397.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146290 | NVP-BGJ398(Infigratinib) >98% | 100mg | $542.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146290 | NVP-BGJ398(Infigratinib) >98% | 250mg | $986 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146290 | NVP-BGJ398(Infigratinib) >98% | 1g | $1802 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD46729 | NVP BGJ 398 | 10mg | $80 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD46729 | NVP BGJ 398 | 50mg | $160 | 2021-12-16 | Buy |
| Cayman Chemical | 19157 | BGJ398 ≥98% | 1mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 19157 | BGJ398 ≥98% | 5mg | $120 | 2024-03-01 | Buy |
Properties
Melting point :>211°C (dec.)
Boiling point :747.9±60.0 °C(Predicted)
Density :1.354
storage temp. :-20°C
solubility :Soluble in DMSO (up to 5 mg/ml)
form :White solid.
pka :11.02±0.70(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Boiling point :747.9±60.0 °C(Predicted)
Density :1.354
storage temp. :-20°C
solubility :Soluble in DMSO (up to 5 mg/ml)
form :White solid.
pka :11.02±0.70(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Safety Information
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Description
BGJ398 is an orally available inhibitor of human FGFRs (IC50s = 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively). It inhibits FGFR4 and VEGFR2 with IC50 values of 60 and 180 nM, respectively, and displays comparatively little activity towards Abl, Fyn, Kit, Lck, Lyn, and Yes (IC50s = 0.3-2.5 μM). BGJ398 has been shown to suppress proliferation of cancer cells with wild-type FGFR3 overexpression (IC50s = 5, 30, 32, and 15 nM, for RT112, RT4, SW780, and JMSU1 cells, respectively). In an RT112 bladder cancer xenograft mouse model overexpressing wild-type FGFR3, BGJ398 inhibited tumor growth after oral administration of 10-30 mg/kg.More related product prices
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![3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea](https://img.chemicalbook.com/ProductImageEN/2020-1/small/19ad71e7-73a0-43a9-a5bc-6db9903bff82.jpg){kind=small}