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ChemicalBook >> CAS DataBase List >> MCC-555

MCC-555

MCC-555 price.
  • $44 - $942
  • Product name: MCC-555
  • CAS: 161600-01-7
  • MF: C21H16FNO3S
  • MW: 381.42
  • EINECS:
  • MDL Number:MFCD00931223
  • Synonyms:MCC-555;NETOGLITAZONE,2,4-THIAZOLIDINEDIONE, 5-[[6-[(2-FLUOROPHENYL)METHOXY]-2-NAPHTHALENYL]METHYL]-;Isaglitazone;Netoglitazone;RWJ 241947;5-[[6-[(2-FLUOROPHENYL)METHOXY]-2-NAPHTHALENYL]METHYL]-2,4-THIAZOLIDINEDIONE;5-[[6-[(2-fluorophenyl)methoxy]naphthalen-2-yl]methyl]-1,3-thiazolidine-2,4-dione;5-((6-((2-Fluorobenzyl)oxy)naphthalen-2-yl)methyl)thiazolidine-2,4-dione
12 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number2791CB
  • Product descriptionNetoglitazone
  • Packaging10mg
  • Price$942
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0009623
  • Product descriptionNETOGLITAZONE 95.00%
  • Packaging5MG
  • Price$578.25
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4892
  • Product descriptionMCC-555
  • Packaging1mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4892
  • Product descriptionMCC-555
  • Packaging5mg
  • Price$486
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4892
  • Product descriptionMCC-555
  • Packaging10mg
  • Price$865
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number70735
  • Product descriptionMCC-555
  • Packaging25mg
  • Price$0
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number70735
  • Product descriptionMCC-555 ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70735
  • Product descriptionMCC-555 ≥98%
  • Packaging5mg
  • Price$117
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70735
  • Product descriptionMCC-555 ≥98%
  • Packaging10mg
  • Price$214
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0896
  • Product descriptionMCC-555 ≥98% (HPLC)
  • Packaging5mg
  • Price$97.6
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0896
  • Product descriptionMCC-555 ≥98% (HPLC)
  • Packaging25mg
  • Price$382
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberM199780
  • Product descriptionMCC555
  • Packaging10mg
  • Price$625
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2791CB Netoglitazone 10mg $942 2021-12-16 Buy
American Custom Chemicals Corporation API0009623 NETOGLITAZONE 95.00% 5MG $578.25 2021-12-16 Buy
ApexBio Technology C4892 MCC-555 1mg $108 2021-12-16 Buy
ApexBio Technology C4892 MCC-555 5mg $486 2021-12-16 Buy
ApexBio Technology C4892 MCC-555 10mg $865 2021-12-16 Buy
Cayman Chemical 70735 MCC-555 25mg $0 2021-12-16 Buy
Cayman Chemical 70735 MCC-555 ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 70735 MCC-555 ≥98% 5mg $117 2024-03-01 Buy
Cayman Chemical 70735 MCC-555 ≥98% 10mg $214 2024-03-01 Buy
Sigma-Aldrich SML0896 MCC-555 ≥98% (HPLC) 5mg $97.6 2024-03-01 Buy
Sigma-Aldrich SML0896 MCC-555 ≥98% (HPLC) 25mg $382 2024-03-01 Buy
TRC M199780 MCC555 10mg $625 2021-12-16 Buy

Properties

Boiling point :599.5±30.0 °C(Predicted)
Density :1.369±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :6.28±0.50(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P501 Dispose of contents/container to..…

Description

The peroxisome proliferator-activated receptor-γ (PPARγ) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones (TZDs), a group of structurally related synthetic agonists with antidiabetic actions in vivo. Rosiglitazone (BRL49653) is a prototypical TZD and has served as a reference compound for this class. MCC-555 is a structural homolog of rosiglitazone and the other TZDs. MCC-555 binds with about 1/10 the affinity of rosiglitazone to PPARγ. Despite this, MCC-555 is a more potent antidiabetic agent in whole animal experiments than rosiglitazone and several other prototypic TZDs; the ED50 value in these experiments was 2.7 mg/kg for MCC-555 compared with 7.1 mg/kg for rosiglitazone. MCC-555 is therefore a unique new member of the TZD class and may be useful in differentiating some of the multiple activities attributed to this class of compounds.

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