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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
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ChemicalBook >> CAS DataBase List >> ML 18

ML 18

ML 18 price.
  • $35 - $1200
  • Product name: ML 18
  • CAS: 1422269-30-4
  • MF: C32H35N5O5
  • MW: 569.66
  • EINECS:-0
  • MDL Number:
  • Synonyms:ML 18;BRS-3 antagonist;ML18;ML-18;ML 18;BRS-3 ANTAGONIST;1422269-30-4;ML18, >98%;(2S)-3-(1H-INDOL-3-YL)-N-{[1-(4-METHOXYPHENYL)CYCLOHEXYL]METHYL}-2-{[(4-NITROPHENYL)CARBAMOYL]AMINO}PROPANAMIDE;(S)-3-(1H-Indol-3-yl)-N-((1-(4-methoxyphenyl)cyclohexyl)methyl)-2-(3-(4-nitrophenyl)ureido)propanamide;Bombesin Receptor,ML-18,ML 18,inhibit,Inhibitor,ML18
Price18 Properties Safety Information Description
18 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • TRC
Package
  • 500μg
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number3037EC
  • Product description(2S)-3-(1H-Indol-3-yl)-N-[[1-(4-methoxyphenyl)cyclohexyl]methyl]-2-[(4-nitrophenyl)carbamoylamino]propanamide
  • Packaging5mg
  • Price$134
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA708758
  • Product descriptionML-18 98%
  • Packaging10mg
  • Price$151
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA708758
  • Product descriptionML-18 98%
  • Packaging5mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA708758
  • Product descriptionML-18 98%
  • Packaging2mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA708758
  • Product descriptionML-18 98%
  • Packaging50mg
  • Price$257
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA708758
  • Product descriptionML-18 98%
  • Packaging25mg
  • Price$197
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number27319
  • Product descriptionML-18
  • Packaging10mg
  • Price$315
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27319
  • Product descriptionML-18
  • Packaging1mg
  • Price$67
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27319
  • Product descriptionML-18
  • Packaging500μg
  • Price$35
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27319
  • Product descriptionML-18
  • Packaging5mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6869
  • Product descriptionML-18 98.84%
  • Packaging5mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6869
  • Product descriptionML-18 98.84%
  • Packaging25mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6869
  • Product descriptionML-18 98.84%
  • Packaging10mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6869
  • Product descriptionML-18 98.84%
  • Packaging50mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6869
  • Product descriptionML-18 98.84%
  • Packaging100mg
  • Price$1200
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN24208
  • Product descriptionML-18
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3037EC (2S)-3-(1H-Indol-3-yl)-N-[[1-(4-methoxyphenyl)cyclohexyl]methyl]-2-[(4-nitrophenyl)carbamoylamino]propanamide 5mg $134 2021-12-16 Buy
Ambeed A708758 ML-18 98% 10mg $151 2021-12-16 Buy
Ambeed A708758 ML-18 98% 5mg $116 2021-12-16 Buy
Ambeed A708758 ML-18 98% 2mg $65 2021-12-16 Buy
Ambeed A708758 ML-18 98% 50mg $257 2021-12-16 Buy
Ambeed A708758 ML-18 98% 25mg $197 2021-12-16 Buy
Cayman Chemical 27319 ML-18 10mg $315 2024-03-01 Buy
Cayman Chemical 27319 ML-18 1mg $67 2024-03-01 Buy
Cayman Chemical 27319 ML-18 500μg $35 2024-03-01 Buy
Cayman Chemical 27319 ML-18 5mg $193 2024-03-01 Buy
ChemScene CS-6869 ML-18 98.84% 5mg $180 2021-12-16 Buy
ChemScene CS-6869 ML-18 98.84% 25mg $550 2021-12-16 Buy
ChemScene CS-6869 ML-18 98.84% 10mg $250 2021-12-16 Buy
ChemScene CS-6869 ML-18 98.84% 50mg $950 2021-12-16 Buy
ChemScene CS-6869 ML-18 98.84% 100mg $1200 2021-12-16 Buy
CSNpharm CSN24208 ML-18 5mg $70 2021-12-16 Buy
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Properties

Boiling point :821.8±65.0 °C(Predicted)
Density :1.291±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble
form :A solid
pka :11.99±0.46(Predicted)
color :White to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ML-18 is a non-peptide bombesin receptor subtype 3 (BB3) antagonist that inhibits [125I]BA1 binding to NCI-H1299 lung cancer cells transfected with human BB3 receptors (IC50 = 4.8 μM). It is selective for BB3 over the gastrin releasing peptide receptor (GRPR) and the neuromedin B receptor (NMBR) with IC50 values of 16 and >100 μM, respectively, in a radioligand binding assay. ML-18 (16 μM) reversibly inhibits BA1-induced increases in cytosolic calcium in NCI-H1299 cells. It also inhibits BA1-induced phosphorylation of ERK and EGFR and reduces proliferation of NCI-H1299 cells.

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