Mirin
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- $44 - $1021.14
- Product name: Mirin
- CAS: 299953-00-7
- MF: C10H8N2O2S
- MW: 220.25
- EINECS:683-709-3
- MDL Number:MFCD05885480
- Synonyms:5-(4-Hydroxybenzylidene)-2-iminothiazolidin-4-one;MRN-ATM Pathway Inhibitor, Mirin;(5E)-5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one;(E)-5-(4-hydroxybenzylidene)-2-iminothiazolidin-4-one;4(5H)-Thiazolone, 2-amino-5-[(4-hydroxyphenyl)methylene]-;Mirin >=98% (HPLC), powder
17 prices
Selected condition：
Brand
- AK Scientific
- Alfa Aesar
- American Custom Chemicals Corporation
- Cayman Chemical
- Matrix Scientific
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100MG
- 250mg
- 1g
- 2.500g
- ManufacturerAK Scientific
- Product number1860AH
- Product descriptionMirin
- Packaging1g
- Price$656
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67462
- Product descriptionMirin, 95%
- Packaging5mg
- Price$74.9
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67462
- Product descriptionMirin, 95%
- Packaging10mg
- Price$128
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67462
- Product descriptionMirin, 95%
- Packaging50mg
- Price$564
- Updated2023-06-20
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberFFG0000171
- Product descriptionMIRIN 95.00%
- Packaging5MG
- Price$607.3
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberFFG0000171
- Product descriptionMIRIN 95.00%
- Packaging100MG
- Price$1021.14
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13208
- Product descriptionMirin ≥95%
- Packaging5mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13208
- Product descriptionMirin ≥95%
- Packaging10mg
- Price$84
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13208
- Product descriptionMirin ≥95%
- Packaging50mg
- Price$299
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13208
- Product descriptionMirin ≥95%
- Packaging100mg
- Price$510
- Updated2024-03-01
- Buy
- ManufacturerMatrix Scientific
- Product number140160
- Product description(5E)-5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one 95+%
- Packaging1g
- Price$449
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number140160
- Product description(5E)-5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one 95+%
- Packaging2.500g
- Price$980
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberM9948
- Product descriptionMirin ≥98% (HPLC), powder
- Packaging5mg
- Price$86
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number475954
- Product descriptionMRN-ATM Pathway Inhibitor, Mirin
- Packaging10mg
- Price$172
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberM9948
- Product descriptionMirin ≥98% (HPLC), powder
- Packaging25mg
- Price$212.4
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberH852765
- Product description(5E)-5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one
- Packaging25mg
- Price$65
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1860AH | Mirin | 1g | $656 | 2021-12-16 | Buy |
| Alfa Aesar | J67462 | Mirin, 95% | 5mg | $74.9 | 2023-06-20 | Buy |
| Alfa Aesar | J67462 | Mirin, 95% | 10mg | $128 | 2023-06-20 | Buy |
| Alfa Aesar | J67462 | Mirin, 95% | 50mg | $564 | 2023-06-20 | Buy |
| American Custom Chemicals Corporation | FFG0000171 | MIRIN 95.00% | 5MG | $607.3 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | FFG0000171 | MIRIN 95.00% | 100MG | $1021.14 | 2021-12-16 | Buy |
| Cayman Chemical | 13208 | Mirin ≥95% | 5mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 13208 | Mirin ≥95% | 10mg | $84 | 2024-03-01 | Buy |
| Cayman Chemical | 13208 | Mirin ≥95% | 50mg | $299 | 2024-03-01 | Buy |
| Cayman Chemical | 13208 | Mirin ≥95% | 100mg | $510 | 2024-03-01 | Buy |
| Matrix Scientific | 140160 | (5E)-5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one 95+% | 1g | $449 | 2021-12-16 | Buy |
| Matrix Scientific | 140160 | (5E)-5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one 95+% | 2.500g | $980 | 2021-12-16 | Buy |
| Sigma-Aldrich | M9948 | Mirin ≥98% (HPLC), powder | 5mg | $86 | 2024-03-01 | Buy |
| Sigma-Aldrich | 475954 | MRN-ATM Pathway Inhibitor, Mirin | 10mg | $172 | 2024-03-01 | Buy |
| Sigma-Aldrich | M9948 | Mirin ≥98% (HPLC), powder | 25mg | $212.4 | 2024-03-01 | Buy |
| TRC | H852765 | (5E)-5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one | 25mg | $65 | 2021-12-16 | Buy |
Properties
Melting point :295-297 °C(Solv: ethanol (64-17-5))
Boiling point :441.6±55.0 °C(Predicted)
Density :1.49±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
form :Reddish orange powder
pka :9.15±0.30(Predicted)
color :red to orange
Sensitive :Moisture Sensitive
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Boiling point :441.6±55.0 °C(Predicted)
Density :1.49±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
form :Reddish orange powder
pka :9.15±0.30(Predicted)
color :red to orange
Sensitive :Moisture Sensitive
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
The Mre11-Rad50-Nbs1 (MRN) complex acts as a DNA damage sensor, maintains genome stability during DNA replication, and activates and recruits ataxia-telangiectasia mutated (ATM) to damaged DNA. The genes that encode the MRN proteins are all essential for cell viability, so functional studies of MRN cannot involve deletion of these genes. Mirin is an inhibitor of MRN, inhibiting MRN-dependent phosphorylation of histone H2AX (IC50 = 66 μM). Through its effects on MRN, mirin prevents activation of ATM. Inhibition of MRN centers on the ability of mirin to block the nuclease activity of Mre11, rather than altering DNA-binding or MRN complex formation. In cells, mirin induces G2 arrest, abolishes the radiation-induced G2/M checkpoint, and prevents homology-directed repair of DNA damage.More related product prices
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