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ChemicalBook >> CAS DataBase List >> Molidustat(BAY 85-3934)

Molidustat(BAY 85-3934)

Molidustat(BAY 85-3934) price.
  • $33 - $900
  • Product name: Molidustat(BAY 85-3934)
  • CAS: 1154028-82-6
  • MF: C13H14N8O2
  • MW: 314.3
  • EINECS:815-038-0
  • MDL Number:MFCD28411428
  • Synonyms:Molidustat(BAY 85-3934);BAY 85-3934;MOLIDUSTAT;2-[6-(4-Morpholinyl)-4-pyrimidinyl]-4-(1H-1,2,3-triazol-1-yl)-1,2-dihydro-3H-pyrazol-3-one;2-[6-(Morpholin-4-yl)pyrimidin-4-yl]-4-(1H-1,2,3-triazol-1-yl)-1,2-dihydro-3H-pyrazol-3-one;Somatoprim;2-(6-morpholinopyrimidin-4-yl)-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-3(2H)-one;1,2-dihydro-2-[6-(4-morpholinyl)-4-pyrimidinyl]-4-(1H-1,2,3-triazol-1-yl)-3H-pyrazol-3-one
22 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 10mM(in 1mL DMF)
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number9756BB
  • Product descriptionMolidustat
  • Packaging5mg
  • Price$249
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5861
  • Product descriptionMolidustat(BAY85-3934)
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5861
  • Product descriptionMolidustat(BAY85-3934)
  • Packaging10mM(in 1mL DMF)
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5861
  • Product descriptionMolidustat(BAY85-3934)
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5861
  • Product descriptionMolidustat(BAY85-3934)
  • Packaging50mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5861
  • Product descriptionMolidustat(BAY85-3934)
  • Packaging100mg
  • Price$900
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15297
  • Product descriptionBAY 85-3934 ≥95%
  • Packaging1mg
  • Price$33
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15297
  • Product descriptionBAY 85-3934 ≥95%
  • Packaging5mg
  • Price$137
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15297
  • Product descriptionBAY 85-3934 ≥95%
  • Packaging10mg
  • Price$223
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15297
  • Product descriptionBAY 85-3934 ≥95%
  • Packaging25mg
  • Price$396
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM163822
  • Product description2-(6-morpholinopyrimidin-4-yl)-4-(1H-1,2,3-triazol-1-yl)-1,2-dihydro-3H-pyrazol-3-one 98%
  • Packaging100mg
  • Price$407
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4046
  • Product descriptionMolidustat 99.26%
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4046
  • Product descriptionMolidustat 99.26%
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4046
  • Product descriptionMolidustat 99.26%
  • Packaging50mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4046
  • Product descriptionMolidustat 99.26%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004461
  • Product descriptionMolidustat 98+%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9756BB Molidustat 5mg $249 2021-12-16 Buy
ApexBio Technology B5861 Molidustat(BAY85-3934) 5mg $100 2021-12-16 Buy
ApexBio Technology B5861 Molidustat(BAY85-3934) 10mM(in 1mL DMF) $100 2021-12-16 Buy
ApexBio Technology B5861 Molidustat(BAY85-3934) 10mg $150 2021-12-16 Buy
ApexBio Technology B5861 Molidustat(BAY85-3934) 50mg $600 2021-12-16 Buy
ApexBio Technology B5861 Molidustat(BAY85-3934) 100mg $900 2021-12-16 Buy
Cayman Chemical 15297 BAY 85-3934 ≥95% 1mg $33 2024-03-01 Buy
Cayman Chemical 15297 BAY 85-3934 ≥95% 5mg $137 2024-03-01 Buy
Cayman Chemical 15297 BAY 85-3934 ≥95% 10mg $223 2024-03-01 Buy
Cayman Chemical 15297 BAY 85-3934 ≥95% 25mg $396 2024-03-01 Buy
Chemenu CM163822 2-(6-morpholinopyrimidin-4-yl)-4-(1H-1,2,3-triazol-1-yl)-1,2-dihydro-3H-pyrazol-3-one 98% 100mg $407 2021-12-16 Buy
ChemScene CS-4046 Molidustat 99.26% 5mg $120 2021-12-16 Buy
ChemScene CS-4046 Molidustat 99.26% 10mg $180 2021-12-16 Buy
ChemScene CS-4046 Molidustat 99.26% 50mg $400 2021-12-16 Buy
ChemScene CS-4046 Molidustat 99.26% 100mg $550 2021-12-16 Buy
Crysdot CD31004461 Molidustat 98+% 5mg $60 2021-12-16 Buy

Properties

Boiling point :589.2±60.0 °C(Predicted)
Density :1.67±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥5.68 mg/mL in DMF
form :solid
pka :5.38±0.37(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P314 Get medical advice/attention if you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Hypoxia-inducible factor (HIF) is the major transcription factor involved in erythropoietin gene expression. Because oxygen-dependent degradation of the α subunit of HIF suppresses erythropoietin expression, stimulation of erythropoiesis by agents that prevent degradation of HIF has been one strategy for managing anemia. BAY 85-3934 stabilizes HIF from degradation in the proteasome by inhibiting HIF-1α prolyl hydroxylase (IC50 = 0.49 μM). Inhibition of HIF prolyl hydroxylase by BAY 85-3934 has been shown to increase endogenous production of erythropoietin. This compound has been investigated in clinical trial for treatment of patients with anemia associated with chronic kidney disease and/or end-stage renal disease.

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