NF449
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- $140.7 - $992
- Product name: NF449
- CAS: 389142-38-5
- MF: C41H32N6O29S8
- MW: 1329.24
- EINECS:
- MDL Number:MFCD03791135
- Synonyms:4,4',4'',4'''-[CARBONYLBIS(IMINO-5,1,3-BENZENETRIYL-BIS(CARBONYLIMINO))]TETRAKIS-1,3-BENZENEDISULFONIC ACID, OCTASODIUM SALT;4,4',4'',4'''-[CARBONYL-BIS[IMINO-5,1,3-BENZENETRIYL BIS-(CARBONYL-IMINO)]]TETRAKIS(BENZENE-1,3-DISULFONIC ACID) OCTASODIUM SALT;4,4',4'',4'''-[CARBONYL-BIS[IMINO-5,1,3-BENZENETRIYL BIS-(CARBONYLIMINO)]]TETRAKIS-(BENZENE-1,3-DISULFONIC ACID, 8NA);NF449;NF449 OCTASODIUM SALT;4,4',4'',4'''-(Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino)))tetrakis-1,3-benzenedisulfonicacid,octasodium;4,4μ,4,4μ-[Carbonylbis[imino-5,1,3-benzenetriyl bis(carbonyl-imino)]]tetrakis(benzene-1,3-disulfonic acid) octasodium salt;4,4',4'',4'''-[Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzenedisulfonic acid octasodium salt
7 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Sigma-Aldrich
- Tocris
- Usbiological
Package
- 50
- 1MG
- 5MG
- 10
- 10mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0009857
- Product descriptionNF 449 95.00%
- Packaging1MG
- Price$140.7
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0009857
- Product descriptionNF 449 95.00%
- Packaging5MG
- Price$505.16
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number480420
- Product descriptionNF449
- Packaging10mg
- Price$227.55
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number1391
- Product descriptionNF449
- Packaging10
- Price$236
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number1391
- Product descriptionNF449
- Packaging50
- Price$992
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number165610
- Product descriptionNF449
- Packaging10mg
- Price$403
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number255975
- Product descriptionNF 449
- Packaging10mg
- Price$489
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0009857 | NF 449 95.00% | 1MG | $140.7 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009857 | NF 449 95.00% | 5MG | $505.16 | 2021-12-16 | Buy |
| Sigma-Aldrich | 480420 | NF449 | 10mg | $227.55 | 2021-12-16 | Buy |
| Tocris | 1391 | NF449 | 10 | $236 | 2021-12-16 | Buy |
| Tocris | 1391 | NF449 | 50 | $992 | 2021-12-16 | Buy |
| Usbiological | 165610 | NF449 | 10mg | $403 | 2021-12-16 | Buy |
| Usbiological | 255975 | NF 449 | 10mg | $489 | 2021-12-16 | Buy |
Properties
Melting point :>300°C
Density :1.991±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :H2O: soluble
form :solid
pka :-2.03±0.50(Predicted)
color :white
Stability :Hygroscopic
Density :1.991±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :H2O: soluble
form :solid
pka :-2.03±0.50(Predicted)
color :white
Stability :Hygroscopic
Safety Information
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Description
NF 449 is a selective Gsα-subunit G-protein antagonist which reduces the association rate of guanosine 5'-[γ-thio]triphosphate ([35S]GTP[γS]) binding to Gα s -s (Gs&alpha-s) and inhibits the stimulation of adenylyl cyclase activity in S49 cyc- membranes. In addition, NF 449 interferes with binding between the Adenosine A1-R (A1-adenosine receptor) and its cognate G proteins (Gi/Go). Alternate studies suggest that NF449 inhibits a wide array of P2 receptors such as P2X3, P2Y1, and P2Y2, while showing the highest selectivity towards P2X1. Furthermore, NF449 can disrupt the coupling of β-AR (β-adrenergic receptors).Related product price
- 4-Amino-1,3-benzenedisulfonic acid
$9-720 - NF449
$140.7-992 - 15898-43-8
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