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ChemicalBook >> CAS DataBase List >> NSC 600157

NSC 600157

NSC 600157 price.
  • $35 - $1700
  • Product name: NSC 600157
  • CAS: 31083-55-3
  • MF: C15H9NO2
  • MW: 235.24
  • EINECS:
  • MDL Number:MFCD00435709
  • Synonyms:2-(3-Pyridinylmethylene)-1H-indene-1,3(2H)-dione;2-(3-Pyridylmethylene)-1,3-indandione;NSC 600157;PRT4165;PRT 4165(NSC 600157);PRT 4165; PRT-4165; NSC600157; NSC-600157; NSC 600157; 2-(pyridin-3-ylmethylidene)indene-1,3-dione;1H-Indene-1,3(2H)-dione, 2-(3-pyridinylmethylene)-
Price30 Properties Safety Information Description
30 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • Usbiological
Package
  • 50
  • 10mg
  • 5mg
  • 10
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2917CB
  • Product description1,3-Indandione,2-(3-pyridylmethylene)-
  • Packaging100mg
  • Price$143
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5089
  • Product descriptionPRT4165
  • Packaging50mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA295342
  • Product descriptionPRT4165 98+%
  • Packaging5mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA295342
  • Product descriptionPRT4165 98+%
  • Packaging10mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA295342
  • Product descriptionPRT4165 98+%
  • Packaging25mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA295342
  • Product descriptionPRT4165 98+%
  • Packaging50mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA295342
  • Product descriptionPRT4165 98+%
  • Packaging100mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA295342
  • Product descriptionPRT4165 98+%
  • Packaging1g
  • Price$1700
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5797
  • Product descriptionPRT4165
  • Packaging10mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS509539
  • Product descriptionPRT4165
  • Packaging10mg
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1953
  • Product descriptionPRT4165-NSC600157 99%
  • Packaging50mg
  • Price$231
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19093
  • Product descriptionPRT4165 ≥98%
  • Packaging5mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19093
  • Product descriptionPRT4165 ≥98%
  • Packaging10mg
  • Price$85
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19093
  • Product descriptionPRT4165 ≥98%
  • Packaging25mg
  • Price$177
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5436
  • Product descriptionPRT4165 ≥98.0%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5436
  • Product descriptionPRT4165 ≥98.0%
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2917CB 1,3-Indandione,2-(3-pyridylmethylene)- 100mg $143 2021-12-16 Buy
AK Scientific SYN5089 PRT4165 50mg $400 2021-12-16 Buy
Ambeed A295342 PRT4165 98+% 5mg $35 2021-12-16 Buy
Ambeed A295342 PRT4165 98+% 10mg $59 2021-12-16 Buy
Ambeed A295342 PRT4165 98+% 25mg $119 2021-12-16 Buy
Ambeed A295342 PRT4165 98+% 50mg $154 2021-12-16 Buy
Ambeed A295342 PRT4165 98+% 100mg $200 2021-12-16 Buy
Ambeed A295342 PRT4165 98+% 1g $1700 2021-12-16 Buy
ApexBio Technology B5797 PRT4165 10mg $60 2021-12-16 Buy
Arctom AS509539 PRT4165 10mg $58 2021-12-16 Buy
Axon Medchem Axon1953 PRT4165-NSC600157 99% 50mg $231 2021-12-16 Buy
Cayman Chemical 19093 PRT4165 ≥98% 5mg $57 2024-03-01 Buy
Cayman Chemical 19093 PRT4165 ≥98% 10mg $85 2024-03-01 Buy
Cayman Chemical 19093 PRT4165 ≥98% 25mg $177 2024-03-01 Buy
ChemScene CS-5436 PRT4165 ≥98.0% 5mg $50 2021-12-16 Buy
ChemScene CS-5436 PRT4165 ≥98.0% 10mg $70 2021-12-16 Buy
Next Last

Properties

Melting point :154-161 °C(Solv: ethanol (64-17-5))
Boiling point :377.63°C (rough estimate)
Density :1.1757 (rough estimate)
refractive index :1.6231 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :3.24±0.12(Predicted)
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

BMI1/RING1A and BMI1/RNF2 are E3 ubiquitin ligase complexes that mediate the monoubiquitination of histone 2A (H2A). This is an essential function of polycomb repressive complex 1 (PRC1). PRT4165 is an inhibitor of the ubiquitin ligase activity of PRC1. It blocks BMI1/RING1A self-ubiquitination (IC50 = 3.9 μM), as well as polyubiquitination of topoisomerase 2α in cells. PRT4165 inhibits ubiquitination of H2A by either RNF2 or RING1. Through these actions, PRT4165 prevents the accumulation of detectable ubiquitin at DNA double-strand breaks, the retention of response proteins around breaks, and the repair of breaks.

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Suppliers and manufacturers

career henan chemical co
2-(pyridin-3-ylmethylidene)indene-1,3-dione
$1.00 /1KG
2-(pyridin-3-ylmethylidene)indene-1,3-dione CAS:31083-55-3
TargetMol Chemicals Inc.
PRT4165
$38.00 /5mg
PRT4165 CAS:31083-55-3
ATK CHEMICAL COMPANY LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
GIHI CHEMICALS CO.,LIMITED
Shanghai Acmec Biochemical Technology Co., Ltd.