Nutlin-3b
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- $62 - $2600
- Product name: Nutlin-3b
- CAS: 675576-97-3
- MF: C30H30Cl2N4O4
- MW: 581.49
- EINECS:
- MDL Number:MFCD11977784
- Synonyms:Nutlin-3b;4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone;2-Piperazinone, 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-;4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone Nutlin 3b;NUTLIN-3B;NUTLIN 3B;4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imid;CS-986;4-((4R,5S)-4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one
18 prices
Selected condition：
Brand
- ApexBio Technology
- Axon Medchem
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 2x5mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerApexBio Technology
- Product numberA2005
- Product descriptionNutlin-3b
- Packaging5mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1881
- Product descriptionNutlin-3b-(+)-Nutlin-3 99%
- Packaging2mg
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1881
- Product descriptionNutlin-3b-(+)-Nutlin-3 99%
- Packaging2x5mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10009816
- Product description(+)-Nutlin-3 ≥98%
- Packaging1mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10009816
- Product description(+)-Nutlin-3 ≥98%
- Packaging5mg
- Price$153
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10009816
- Product description(+)-Nutlin-3 ≥98%
- Packaging10mg
- Price$245
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10009816
- Product description(+)-Nutlin-3 ≥98%
- Packaging25mg
- Price$536
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0727
- Product descriptionNutlin-3b ≥98.0%
- Packaging5mg
- Price$144
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0727
- Product descriptionNutlin-3b ≥98.0%
- Packaging10mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0727
- Product descriptionNutlin-3b ≥98.0%
- Packaging50mg
- Price$900
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31001095
- Product descriptionNutlin3b 98+%
- Packaging5mg
- Price$102
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31001095
- Product descriptionNutlin3b 98+%
- Packaging10mg
- Price$158
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31001095
- Product descriptionNutlin3b 98+%
- Packaging50mg
- Price$655
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8455
- Product descriptionNutlin-3b >98%
- Packaging100mg
- Price$700
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8455
- Product descriptionNutlin-3b >98%
- Packaging250mg
- Price$1400
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8455
- Product descriptionNutlin-3b >98%
- Packaging1g
- Price$2600
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ApexBio Technology | A2005 | Nutlin-3b | 5mg | $130 | 2021-12-16 | Buy |
| Axon Medchem | Axon1881 | Nutlin-3b-(+)-Nutlin-3 99% | 2mg | $99 | 2021-12-16 | Buy |
| Axon Medchem | Axon1881 | Nutlin-3b-(+)-Nutlin-3 99% | 2x5mg | $220 | 2021-12-16 | Buy |
| Cayman Chemical | 10009816 | (+)-Nutlin-3 ≥98% | 1mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 10009816 | (+)-Nutlin-3 ≥98% | 5mg | $153 | 2024-03-01 | Buy |
| Cayman Chemical | 10009816 | (+)-Nutlin-3 ≥98% | 10mg | $245 | 2024-03-01 | Buy |
| Cayman Chemical | 10009816 | (+)-Nutlin-3 ≥98% | 25mg | $536 | 2024-03-01 | Buy |
| ChemScene | CS-0727 | Nutlin-3b ≥98.0% | 5mg | $144 | 2021-12-16 | Buy |
| ChemScene | CS-0727 | Nutlin-3b ≥98.0% | 10mg | $240 | 2021-12-16 | Buy |
| ChemScene | CS-0727 | Nutlin-3b ≥98.0% | 50mg | $900 | 2021-12-16 | Buy |
| Crysdot | CD31001095 | Nutlin3b 98+% | 5mg | $102 | 2021-12-16 | Buy |
| Crysdot | CD31001095 | Nutlin3b 98+% | 10mg | $158 | 2021-12-16 | Buy |
| Crysdot | CD31001095 | Nutlin3b 98+% | 50mg | $655 | 2021-12-16 | Buy |
| DC Chemicals | DC8455 | Nutlin-3b >98% | 100mg | $700 | 2021-12-16 | Buy |
| DC Chemicals | DC8455 | Nutlin-3b >98% | 250mg | $1400 | 2021-12-16 | Buy |
| DC Chemicals | DC8455 | Nutlin-3b >98% | 1g | $2600 | 2021-12-16 | Buy |
Properties
Density :1.36
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥55.5 mg/mL in EtOH; ≥57.25 mg/mL in DMSO
form :crystalline solid
pka :14.35±0.20(Predicted)
color :Off-white to yellow
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥55.5 mg/mL in EtOH; ≥57.25 mg/mL in DMSO
form :crystalline solid
pka :14.35±0.20(Predicted)
color :Off-white to yellow
Safety Information
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Description
(+)-Nutlin-3 is the enantiomer and less active form of the p53-Mdm2 protein-protein interaction inhibitor (–)-nutlin-3 . It inhibits the interaction between p53 and Mdm2 150-fold less potently than (–)-nutlin-3 with an IC50 value of 13.6 μM. (+)-Nutlin-3 has been used as a negative control for the p53-modulating activity of (–)-nutlin-3 in cancer cells.Related product price
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