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ChemicalBook >> CAS DataBase List >> 6-(2,6-DICHLORO-PHENYL)-2-(4-FLUORO-3-METHYL-PHENYLAMINO)-8-METHYL-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE

6-(2,6-DICHLORO-PHENYL)-2-(4-FLUORO-3-METHYL-PHENYLAMINO)-8-METHYL-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE

6-(2,6-DICHLORO-PHENYL)-2-(4-FLUORO-3-METHYL-PHENYLAMINO)-8-METHYL-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE price.
  • $100 - $675
  • Product name: 6-(2,6-DICHLORO-PHENYL)-2-(4-FLUORO-3-METHYL-PHENYLAMINO)-8-METHYL-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE
  • CAS: 287204-45-9
  • MF: C21H15Cl2FN4O
  • MW: 429.27
  • EINECS:
  • MDL Number:MFCD10565929
  • Synonyms:6-(2,6-DICHLORO-PHENYL)-2-(4-FLUORO-3-METHYL-PHENYLAMINO)-8-METHYL-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE;PD 180790;PD 180970;PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, 6-(2,6-DICHLOROPHENYL)-2-[(4-FLUORO-3-METHYLPHENYL)AMINO]-8-METHYL-;6-(2,6-Dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one;PF-1515965;6-(2,6-dichlorophenyl)-2-(4-fluoro-3-methylanilino)-8-methylpyrido[2,3-d]pyrimidin-7-one;PD-180970,PD180970
8 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Axon Medchem
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number2636BB
  • Product description6-(2,6-Dichlorophenyl)-2-[(4-Fluoro-3-Methylphenyl)amino]-8-Methylpyrido[2,3-D]pyrimidin-7(8h)-One
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8606
  • Product descriptionPD180970
  • Packaging10mg
  • Price$377
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1137
  • Product descriptionPD180970 99%
  • Packaging50mg
  • Price$462
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number71900
  • Product descriptionPD180970
  • Packaging10mg
  • Price$675
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPZ0142
  • Product descriptionPD-180970 ≥98% (HPLC)
  • Packaging25mg
  • Price$613
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPZ0142
  • Product descriptionPD-180970 ≥98% (HPLC)
  • Packaging5mg
  • Price$155
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberP217825
  • Product descriptionPD180970
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number462101
  • Product descriptionPD 180970
  • Packaging5mg
  • Price$382
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2636BB 6-(2,6-Dichlorophenyl)-2-[(4-Fluoro-3-Methylphenyl)amino]-8-Methylpyrido[2,3-D]pyrimidin-7(8h)-One 1mg $133 2021-12-16 Buy
ApexBio Technology A8606 PD180970 10mg $377 2021-12-16 Buy
Axon Medchem Axon1137 PD180970 99% 50mg $462 2021-12-16 Buy
Medical Isotopes, Inc. 71900 PD180970 10mg $675 2021-12-16 Buy
Sigma-Aldrich PZ0142 PD-180970 ≥98% (HPLC) 25mg $613 2024-03-01 Buy
Sigma-Aldrich PZ0142 PD-180970 ≥98% (HPLC) 5mg $155 2024-03-01 Buy
TRC P217825 PD180970 5mg $100 2021-12-16 Buy
Usbiological 462101 PD 180970 5mg $382 2021-12-16 Buy

Properties

Boiling point :590.6±60.0 °C(Predicted)
Density :1.449±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
pka :3.02±0.20(Predicted)
form :A solid
color :yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.

Description

PD 180970 is an ATP-competitive inhibitor of p210 tyrosine kinase which selectively induces apoptosis in chronic myeloid leukemia (CML) K562 cells.

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