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ChemicalBook >> CAS DataBase List >> PROTEASOME INHIBITOR I

PROTEASOME INHIBITOR I

PROTEASOME INHIBITOR I price.
  • $28 - $5250
  • Product name: PROTEASOME INHIBITOR I
  • CAS: 158442-41-2
  • MF: C32H50N4O8
  • MW: 618.76
  • EINECS:
  • MDL Number:MFCD00671409
  • Synonyms:CARBOBENZOXY-L-ISOLEUCYL-GAMMA-T-BUTYL-L-GLUTAMYL-L-ALANYL-L-LEUCINAL;BENZYLOXYCARBONYL-L-ISOLEUCYL-[(2S)-2-AMINO-4-(T-BUTYLOXYCARBONYL)BUTANOYL]-L-ALANYL-L-LEUCINAL;PROTEASOME INHIBITOR I;PROTEASOME INHIBITOR I (ALDEHYDE);PROTEASOME INHIBITOR PSI;PSI;N-CBZ-ILE-GLU(O-T-BUTYL)-ALA-LEUCINAL;Z-IE(OTBU)AL-CHO
10 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Chem-Impex
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 1unit
  • 1MG
  • 5mg
  • 25MG
  • 100mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000100
  • Product descriptionPROTEASOME INHIBITOR I 95.00%
  • Packaging25MG
  • Price$479.85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1900
  • Product descriptionPSI
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1900
  • Product descriptionPSI
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1900
  • Product descriptionPSI
  • Packaging10mM(in 1mL DMSO)
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number32787
  • Product descriptionZ-Ile-Glu(OtBu)-Ala-Leu-aldehyde
  • Packaging25MG
  • Price$768.77
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number66848
  • Product descriptionProteasomeInhibitor1
  • Packaging100mg
  • Price$5250
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number539160
  • Product descriptionProteasome Inhibitor I The Proteasome Inhibitor I controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
  • Packaging1MG
  • Price$113
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number539160
  • Product descriptionProteasome Inhibitor I The Proteasome Inhibitor I controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
  • Packaging5MG
  • Price$360
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberP838815
  • Product descriptionProteasomeInhibitor1
  • Packaging100mg
  • Price$4675
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number256358
  • Product descriptionPSI
  • Packaging5mg
  • Price$480
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation INB0000100 PROTEASOME INHIBITOR I 95.00% 25MG $479.85 2021-12-16 Buy
ApexBio Technology A1900 PSI 1unit $28 2021-12-16 Buy
ApexBio Technology A1900 PSI 5mg $100 2021-12-16 Buy
ApexBio Technology A1900 PSI 10mM(in 1mL DMSO) $220 2021-12-16 Buy
Chem-Impex 32787 Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde 25MG $768.77 2021-12-16 Buy
Medical Isotopes, Inc. 66848 ProteasomeInhibitor1 100mg $5250 2021-12-16 Buy
Sigma-Aldrich 539160 Proteasome Inhibitor I The Proteasome Inhibitor I controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. 1MG $113 2024-03-01 Buy
Sigma-Aldrich 539160 Proteasome Inhibitor I The Proteasome Inhibitor I controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. 5MG $360 2024-03-01 Buy
TRC P838815 ProteasomeInhibitor1 100mg $4675 2021-12-16 Buy
Usbiological 256358 PSI 5mg $480 2021-12-16 Buy

Properties

Boiling point :844.2±65.0 °C(Predicted)
Density :1.121±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :≥30.6 mg/mL in DMSO; insoluble in H2O; ≥48.7 mg/mL in EtOH
form :solid
pka :11.12±0.46(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Proteasome Inhibitor is a synthetic peptide (Z-Ile-Glu(OtBu)-Ala-Leu-CHO) which selectively inhibits chymotrypsin-like activities in the 26S proteasome (MCP; multicatalytic proteinase complex) in HT4 cells. Additionally, Proteasome Inhibitor acts as anti-neoplytic agent and induces apoptosis in different leukemia cell lines. Furthermore Proteasome Inhibitor is an inhibitor for the deubiquitinating Enzyme, and causes accumulation of ubiquitinylated proteins in neuronal cells. Proteasome Inhibitor prevents the activation of NF-κB in response to TNF-α or okadaic acid through inhibition of IκBα degradation.

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