Paclitaxel
- $30 - $4200
- Product name: Paclitaxel
- CAS: 33069-62-4
- MF: C47H51NO14
- MW: 853.92
- EINECS:608-826-9
- MDL Number:MFCD00869953
- Synonyms:N-BENZYL-BETA-PHENYLISOSERINE ESTER;PACLITAXEL, TAXUS BREVIFOLIA;PACLITAXEL, TAXUS SPECIES;PACLITAXOL;PACLITAXEL;TAXOL(TM);taxol a;TAXOL EQUIVALENT
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Brand
- Adipogen Life Sciences
- AK Scientific
- Alfa Aesar
- ApexBio Technology
- Apolloscientific
- Arctom
- AstaTech
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- BroadPharm
- Cayman Chemical
- Chem-Impex
- ChemScene
- Chemtos
- DC Chemicals
- Iris Biotech GmbH
- IsoSciences
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
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Package
- 5mg
- 20mg
- 25mg
- y0000739
- 1mg
- 10mg
- 10
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 2g
- 5g
- 10g
- 25g
- 1/ G
- 5/ G
- 50
- y0000698
- 10/ G
- y0000719
- y0000700
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0045-M025
- Product descriptionPaclitaxel ≥99%(HPLC)
- Packaging25mg
- Price$92
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ98747
- Product descriptionPaclitaxel
- Packaging250mg
- Price$116
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberA648
- Product descriptionPaclitaxel
- Packaging500mg
- Price$323
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ62734
- Product descriptionPaclitaxel, 99.5+%
- Packaging100mg
- Price$140
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ62734
- Product descriptionPaclitaxel, 99.5+%
- Packaging500mg
- Price$387
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ62734
- Product descriptionPaclitaxel, 99.5+%
- Packaging1g
- Price$727
- Updated2024-03-01
- Buy
- ManufacturerApexBio Technology
- Product numberA4393
- Product descriptionPaclitaxel(Taxol)
- Packaging50mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISC1043
- Product descriptionPaclitaxel-[2H5]
- Packaging1mg
- Price$777
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISC1043
- Product descriptionPaclitaxel-[2H5]
- Packaging5mg
- Price$2802
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN97759
- Product descriptionPaclitaxel
- Packaging20mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerAstaTech
- Product numberN88686
- Product descriptionPaclitaxel 97%
- Packaging1/ G
- Price$166
- Updated2021-12-16
- Buy
- ManufacturerAstaTech
- Product numberN88686
- Product descriptionPaclitaxel 97%
- Packaging5/ G
- Price$499
- Updated2021-12-16
- Buy
- ManufacturerAstaTech
- Product numberN88686
- Product descriptionPaclitaxel 97%
- Packaging10/ G
- Price$749
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1364
- Product descriptionPaclitaxel
- Packaging250mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1364
- Product descriptionPaclitaxel
- Packaging1g
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1364
- Product descriptionPaclitaxel
- Packaging5g
- Price$395
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | AG-CN2-0045-M025 | Paclitaxel ≥99%(HPLC) | 25mg | $92 | 2021-12-16 | Buy |
AK Scientific | J98747 | Paclitaxel | 250mg | $116 | 2021-12-16 | Buy |
AK Scientific | A648 | Paclitaxel | 500mg | $323 | 2021-12-16 | Buy |
Alfa Aesar | J62734 | Paclitaxel, 99.5+% | 100mg | $140 | 2024-03-01 | Buy |
Alfa Aesar | J62734 | Paclitaxel, 99.5+% | 500mg | $387 | 2024-03-01 | Buy |
Alfa Aesar | J62734 | Paclitaxel, 99.5+% | 1g | $727 | 2024-03-01 | Buy |
ApexBio Technology | A4393 | Paclitaxel(Taxol) | 50mg | $50 | 2021-12-16 | Buy |
Apolloscientific | BISC1043 | Paclitaxel-[2H5] | 1mg | $777 | 2021-12-16 | Buy |
Apolloscientific | BISC1043 | Paclitaxel-[2H5] | 5mg | $2802 | 2021-12-16 | Buy |
Arctom | CFN97759 | Paclitaxel | 20mg | $30 | 2021-12-16 | Buy |
AstaTech | N88686 | Paclitaxel 97% | 1/ G | $166 | 2021-12-16 | Buy |
AstaTech | N88686 | Paclitaxel 97% | 5/ G | $499 | 2021-12-16 | Buy |
AstaTech | N88686 | Paclitaxel 97% | 10/ G | $749 | 2021-12-16 | Buy |
AvaChem | 1364 | Paclitaxel | 250mg | $59 | 2021-12-16 | Buy |
AvaChem | 1364 | Paclitaxel | 1g | $105 | 2021-12-16 | Buy |
AvaChem | 1364 | Paclitaxel | 5g | $395 | 2021-12-16 | Buy |
Properties
Melting point :213 °C (dec.)(lit.)
Boiling point :774.66°C (rough estimate)
alpha :D20 -49° (methanol)
Density :0.200
refractive index :-49 ° (C=1, MeOH)
Flash point :9℃
storage temp. :2-8°C
solubility :methanol: 50 mg/mL, clear, colorless
form :powder
pka :11.90±0.20(Predicted)
color :white
Water Solubility :0.3mg/L(37 ºC)
λmax :227nm(MeOH)(lit.)
Merck :14,6982
BRN :1420457
Stability :Stable. Incompatible with strong oxidizing agents. Combustible.
InChIKey :RCINICONZNJXQF-MZXODVADSA-N
LogP :3.950 (est)
CAS DataBase Reference :33069-62-4(CAS DataBase Reference)
EPA Substance Registry System :Paclitaxel (33069-62-4)
Boiling point :774.66°C (rough estimate)
alpha :D20 -49° (methanol)
Density :0.200
refractive index :-49 ° (C=1, MeOH)
Flash point :9℃
storage temp. :2-8°C
solubility :methanol: 50 mg/mL, clear, colorless
form :powder
pka :11.90±0.20(Predicted)
color :white
Water Solubility :0.3mg/L(37 ºC)
λmax :227nm(MeOH)(lit.)
Merck :14,6982
BRN :1420457
Stability :Stable. Incompatible with strong oxidizing agents. Combustible.
InChIKey :RCINICONZNJXQF-MZXODVADSA-N
LogP :3.950 (est)
CAS DataBase Reference :33069-62-4(CAS DataBase Reference)
EPA Substance Registry System :Paclitaxel (33069-62-4)
Safety Information
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Description
Paclitaxel, a potent disruptor of microtubules derived from the bark of the Pacific yew tree, is widely used as a chemotherapeutic compound. Tested against a panel of cervical (HeLa), lung (A549), breast (MCF-7), colon (HT-29), ovarian (OVG-1), and pancreatic (PC-Sh) carcinomas, paclitaxel demonstrates IC50 values ranging from 2.5-7.5 nM. Paclitaxel disrupts multipolar spindle formation, inducing cell cycle arrest in various human cell cancer lines (IC50s = 6.7-18.5 nM) at both prophase and G1. It initiates apoptosis of cancer cells through multiple mechanisms involving p53-dependent and -independent pathways, Bcl-2 family members, cyclin-dependent kinases, and c-Jun N-terminal kinases/stress-activated protein kinases.More related product prices
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