Pimavanserin
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- $22 - $1871.1
- Product name: Pimavanserin
- CAS: 706779-91-1
- MF: C25H34FN3O2
- MW: 427.55
- EINECS:1806241-263-5
- MDL Number:
- Synonyms:Pimavanserin;PIMAVANSERIN/1-(4-FLUOROBENZYL)-3-(4-ISOBUTOXYBENZYL)-1-(1-METHYLPIPERIDIN-4-YL)UREA;Unii-jz963p0dik;Pimavamserin;1-[(4-fluorophenyl)Methyl]-1-(1-Methylpiperidin-4-yl)-3-{[4-(2-Methylpropoxy)phenyl]Methyl}urea;N-(4-Fluorobenzyl)-N-(1-Methylpiperidin-4-yl)-N'-[[4-(2-Methylpropyloxy)phenyl]Methyl]carbaMide;N-[(4-Fluorophenyl)Methyl]-N-(1-Methyl-4-piperidinyl)-N'-[[4-(2-Methylpropoxy)phenyl]Methyl]urea;Urea,N-[(4-fluorophenyl)Methyl]-N-(1-Methyl-4-piperidinyl)-N'-[[4-(2-Methylpropoxy)phenyl]Methyl]-
24 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Chemtos
- Crysdot
- DC Chemicals
- TRC
Package
- 25mg
- 50mg
- 250mg
- 500mg
- 5mg
- 10mg
- 100MG
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product numberY0393
- Product descriptionPimavanserin
- Packaging5mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ97003
- Product descriptionPimavanserin
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003848
- Product descriptionPIMAVANSERIN 95.00%
- Packaging5MG
- Price$236.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003848
- Product descriptionPIMAVANSERIN 95.00%
- Packaging10MG
- Price$739.2
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003848
- Product descriptionPIMAVANSERIN 95.00%
- Packaging100MG
- Price$1871.1
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB8019
- Product descriptionPimavanserin
- Packaging5mg
- Price$58
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB8019
- Product descriptionPimavanserin
- Packaging10mM(in 1mL DMSO)
- Price$61
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB8019
- Product descriptionPimavanserin
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP27045
- Product descriptionPimavanserin
- Packaging25mg
- Price$62.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP27045
- Product descriptionPimavanserin
- Packaging100mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number23462
- Product descriptionPimavanserin ≥98%
- Packaging5mg
- Price$22
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23462
- Product descriptionPimavanserin ≥98%
- Packaging10mg
- Price$41
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23462
- Product descriptionPimavanserin ≥98%
- Packaging25mg
- Price$86
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23462
- Product descriptionPimavanserin ≥98%
- Packaging50mg
- Price$108
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-3378
- Product descriptionPimavanserin 99.99%
- Packaging25mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3378
- Product descriptionPimavanserin 99.99%
- Packaging50mg
- Price$80
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | Y0393 | Pimavanserin | 5mg | $45 | 2021-12-16 | Buy |
| AK Scientific | J97003 | Pimavanserin | 10mg | $60 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003848 | PIMAVANSERIN 95.00% | 5MG | $236.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003848 | PIMAVANSERIN 95.00% | 10MG | $739.2 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003848 | PIMAVANSERIN 95.00% | 100MG | $1871.1 | 2021-12-16 | Buy |
| ApexBio Technology | B8019 | Pimavanserin | 5mg | $58 | 2021-12-16 | Buy |
| ApexBio Technology | B8019 | Pimavanserin | 10mM(in 1mL DMSO) | $61 | 2021-12-16 | Buy |
| ApexBio Technology | B8019 | Pimavanserin | 10mg | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FP27045 | Pimavanserin | 25mg | $62.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FP27045 | Pimavanserin | 100mg | $150 | 2021-12-16 | Buy |
| Cayman Chemical | 23462 | Pimavanserin ≥98% | 5mg | $22 | 2024-03-01 | Buy |
| Cayman Chemical | 23462 | Pimavanserin ≥98% | 10mg | $41 | 2024-03-01 | Buy |
| Cayman Chemical | 23462 | Pimavanserin ≥98% | 25mg | $86 | 2024-03-01 | Buy |
| Cayman Chemical | 23462 | Pimavanserin ≥98% | 50mg | $108 | 2024-03-01 | Buy |
| ChemScene | CS-3378 | Pimavanserin 99.99% | 25mg | $50 | 2021-12-16 | Buy |
| ChemScene | CS-3378 | Pimavanserin 99.99% | 50mg | $80 | 2021-12-16 | Buy |
Properties
Melting point :100-103oC
Boiling point :604.2±55.0 °C(Predicted)
Density :1.15±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Methanol (Slightly)
pka :13.52±0.46(Predicted)
form :Solid
color :Pale Yellow to Pale Orange
InChI :InChI=1S/C25H34FN3O2/c1-19(2)18-31-24-10-6-20(7-11-24)16-27-25(30)29(23-12-14-28(3)15-13-23)17-21-4-8-22(26)9-5-21/h4-11,19,23H,12-18H2,1-3H3,(H,27,30)
InChIKey :RKEWSXXUOLRFBX-UHFFFAOYSA-N
SMILES :N(CC1=CC=C(F)C=C1)(C1CCN(C)CC1)C(NCC1=CC=C(OCC(C)C)C=C1)=O
CAS DataBase Reference :706779-91-1(CAS DataBase Reference)
Boiling point :604.2±55.0 °C(Predicted)
Density :1.15±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Methanol (Slightly)
pka :13.52±0.46(Predicted)
form :Solid
color :Pale Yellow to Pale Orange
InChI :InChI=1S/C25H34FN3O2/c1-19(2)18-31-24-10-6-20(7-11-24)16-27-25(30)29(23-12-14-28(3)15-13-23)17-21-4-8-22(26)9-5-21/h4-11,19,23H,12-18H2,1-3H3,(H,27,30)
InChIKey :RKEWSXXUOLRFBX-UHFFFAOYSA-N
SMILES :N(CC1=CC=C(F)C=C1)(C1CCN(C)CC1)C(NCC1=CC=C(OCC(C)C)C=C1)=O
CAS DataBase Reference :706779-91-1(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||||
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Description
Pimavanserin is a kind of novel oral administrated drug for treatment of Parkinson's psychosis developed by Acadia pharmaceutical Company (US) with the trade name being Pimavanserin. In September 3rd 2014, it has been granted by the US Food and Drug Administration (FDA) for breakthrough therapy certification. Breakthrough therapy certification is created by the FDA for accelerating the development and review of new drugs for treatment of serious or life-threatening diseases.Currently there are about seven millions to ten million of patients of Parkinson's disease worldwide with China contributing 2.6 million, ranking first in the world with 100,000 new patients emerging every year. More than 50% of patients of Parkinson's disease have had psychiatric symptoms (PDP). These psychiatric symptoms are mainly manifested as hallucinations and delusions, bringing greater challenge to the treatment and care for patients of Parkinson's disease. Dopamine is the primary target for the treatment of Parkinson's disease because most antipsychotics drugs will block the dopamine in the brain of the patients of Parkinson’s disease, making their situation of motor dysfunction be even worse, and thus currently not being suitable for these patients.
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Suppliers and manufacturers
Capot Chemical Co.,Ltd.
Shanghai Yingrui Biopharma Co., Ltd.
Nanjing Finetech Chemical Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Shandong chuangyingchemical Co., Ltd.
