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ChemicalBook >> CAS DataBase List >> Pioglitazone

Pioglitazone

Pioglitazone price.
  • $8 - $1504.5
  • Product name: Pioglitazone
  • CAS: 111025-46-8
  • MF: C19H20N2O3S
  • MW: 356.44
  • EINECS:601-029-7
  • MDL Number:MFCD00865504
  • Synonyms:Pioglitazone;5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione;PIOGLITAZONE HCL(5-[[4-[2-(5-ETHYLPYRIDIN-2-YL)ETHOXY]PHENYL]METHYL]THIAZOLIDINE-2,4-DIONE, HCL);PINEPOLLEN;5-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyl]thiazolidine-2,4-dione;Pioglitazone (Actos);2,4-Thiazolidinedione,5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]Methyl]-;Pioglitazone 5-[[4-[2-(5-Ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
37 prices
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Brand
  • AccelPharmtech
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 10mM(in 1mL DMSO)
  • 250mg
  • 500mg
  • 1G
  • 5G
  • 10g
  • 25g
  • ManufacturerAccelPharmtech
  • Product numberAT5958
  • Product descriptionPioglitazone 98%
  • Packaging1G
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAccelPharmtech
  • Product numberAT5958
  • Product descriptionPioglitazone 98%
  • Packaging5G
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-0067-M005
  • Product descriptionPioglitazone ≥98%(1H-NMR).
  • Packaging5mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1393
  • Product descriptionPioglitazone 98%
  • Packaging5g
  • Price$710
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10289
  • Product descriptionPioglitazone
  • Packaging25mg
  • Price$89
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA612927
  • Product description5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione 95%
  • Packaging10mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA612927
  • Product description5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione 95%
  • Packaging50mg
  • Price$12
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA612927
  • Product description5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione 95%
  • Packaging250mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA612927
  • Product description5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione 95%
  • Packaging1g
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA612927
  • Product description5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione 95%
  • Packaging5g
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA612927
  • Product description5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione 95%
  • Packaging25g
  • Price$755
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB2117
  • Product descriptionPioglitazone
  • Packaging100mg
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2117
  • Product descriptionPioglitazone
  • Packaging10mM(in 1mL DMSO)
  • Price$80
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB2117
  • Product descriptionPioglitazone
  • Packaging500mg
  • Price$152
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number1656B
  • Product descriptionPioglitazone
  • Packaging100mg
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1656B
  • Product descriptionPioglitazone
  • Packaging1g
  • Price$119
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AccelPharmtech AT5958 Pioglitazone 98% 1G $50 2021-12-16 Buy
AccelPharmtech AT5958 Pioglitazone 98% 5G $180 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-0067-M005 Pioglitazone ≥98%(1H-NMR). 5mg $30 2021-12-16 Buy
AHH API-1393 Pioglitazone 98% 5g $710 2021-12-16 Buy
AK Scientific J10289 Pioglitazone 25mg $89 2021-12-16 Buy
Ambeed A612927 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione 95% 10mg $8 2021-12-16 Buy
Ambeed A612927 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione 95% 50mg $12 2021-12-16 Buy
Ambeed A612927 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione 95% 250mg $25 2021-12-16 Buy
Ambeed A612927 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione 95% 1g $60 2021-12-16 Buy
Ambeed A612927 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione 95% 5g $226 2021-12-16 Buy
Ambeed A612927 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione 95% 25g $755 2021-12-16 Buy
ApexBio Technology B2117 Pioglitazone 100mg $58 2021-12-16 Buy
ApexBio Technology B2117 Pioglitazone 10mM(in 1mL DMSO) $80 2021-12-16 Buy
ApexBio Technology B2117 Pioglitazone 500mg $152 2021-12-16 Buy
AvaChem 1656B Pioglitazone 100mg $49 2021-12-16 Buy
AvaChem 1656B Pioglitazone 1g $119 2021-12-16 Buy

Properties

Melting point :183-184 C
Boiling point :575.4±45.0 °C(Predicted)
Density :1.260±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly, Heated)
form :White to off-white solid.
pka :6.35±0.50(Predicted)
color :White to Off-White
IARC :2A (Vol. 108) 2016

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Thiazolidinediones (TZDs) are a group of structurally related PPARγ agonists with anti-diabetic actions in vivo. Rosiglitazone (BRL49653) is a prototypical TZD and has served as a reference compound for this class of PPARγ ligands. Pioglitazone is a closely related TZD which also selectively activates PPARγ-1. Pioglitazone is about one tenth as potent as rosiglitazone, with an EC50 of about 500-600 nM for both human and mouse PPARγ. In a transactivation assay using COS-1 cells transfected with full length human PPARα and RXRα, pioglitazone and rosiglitazone exhibit low level activation of PPARα at 1 μM and 5.4- and 4.2-fold activation, respectively, at a concentration of 10 μM.

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