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ChemicalBook >> CAS DataBase List >> R-(+)-Etomoxir

R-(+)-Etomoxir

R-(+)-Etomoxir price.
  • $72 - $2000
  • Product name: R-(+)-Etomoxir
  • CAS: 124083-20-1
  • MF: C17H23ClO4
  • MW: 326.82
  • EINECS:200-258-5
  • MDL Number:MFCD11227266
  • Synonyms:(R)-2-[6-(4-Chlorophenoxy)hexyl]oxirane-2-carboxylic acid ethyl ester;2-Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, ethyl ester, (2R)-;(2S)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylic acid ethyl ester;ethyl (2S)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylate;(2R)-2-[6-(4-Chlorophenoxy)hexyl]-2-oxiranecarboxylic acid ethyl ester;2-Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, ethyl ester, (2R)-(R)-(+)-Etomoxir;S-(+)-ETOMOXIR;(S)-2-[6-(4-CHLOROPHENOXY)HEXYL]OXIRANECARBOXYLIC ACID, ETHYL ESTER
14 prices
Selected condition:
Brand
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 250mg
  • 1g
  • ManufacturerAmbeed
  • Product numberA482603
  • Product description(R)-Ethyl2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate 98+%
  • Packaging1mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA482603
  • Product description(R)-Ethyl2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate 98+%
  • Packaging5mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA482603
  • Product description(R)-Ethyl2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate 98+%
  • Packaging10mg
  • Price$168
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA482603
  • Product description(R)-Ethyl2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate 98+%
  • Packaging25mg
  • Price$386
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA482603
  • Product description(R)-Ethyl2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate 98+%
  • Packaging50mg
  • Price$694
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002658
  • Product descriptionEtomoxir 95.00%
  • Packaging10MG
  • Price$303.45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3404
  • Product descriptionEtomoxir
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3404
  • Product descriptionEtomoxir
  • Packaging50mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004127
  • Product descriptionEtomoxir 98+%
  • Packaging10mg
  • Price$86
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004127
  • Product descriptionEtomoxir 98+%
  • Packaging50mg
  • Price$358
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC24139
  • Product descriptionR(+)-Etomoxirfreeacid >98%
  • Packaging250mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC24139
  • Product descriptionR(+)-Etomoxirfreeacid >98%
  • Packaging1g
  • Price$2000
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number10182
  • Product descriptionS-(+)-Etomoxir
  • Packaging25mg
  • Price$2000
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberE933505
  • Product descriptionR-(+)-Etomoxir
  • Packaging50mg
  • Price$1620
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A482603 (R)-Ethyl2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate 98+% 1mg $72 2021-12-16 Buy
Ambeed A482603 (R)-Ethyl2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate 98+% 5mg $105 2021-12-16 Buy
Ambeed A482603 (R)-Ethyl2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate 98+% 10mg $168 2021-12-16 Buy
Ambeed A482603 (R)-Ethyl2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate 98+% 25mg $386 2021-12-16 Buy
Ambeed A482603 (R)-Ethyl2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate 98+% 50mg $694 2021-12-16 Buy
American Custom Chemicals Corporation API0002658 Etomoxir 95.00% 10MG $303.45 2021-12-16 Buy
ApexBio Technology A3404 Etomoxir 10mg $120 2021-12-16 Buy
ApexBio Technology A3404 Etomoxir 50mg $510 2021-12-16 Buy
Crysdot CD31004127 Etomoxir 98+% 10mg $86 2021-12-16 Buy
Crysdot CD31004127 Etomoxir 98+% 50mg $358 2021-12-16 Buy
DC Chemicals DC24139 R(+)-Etomoxirfreeacid >98% 250mg $950 2021-12-16 Buy
DC Chemicals DC24139 R(+)-Etomoxirfreeacid >98% 1g $2000 2021-12-16 Buy
Medical Isotopes, Inc. 10182 S-(+)-Etomoxir 25mg $2000 2021-12-16 Buy
TRC E933505 R-(+)-Etomoxir 50mg $1620 2021-12-16 Buy

Properties

Melting point :32-34°C
Boiling point :405.0±25.0 °C(Predicted)
Density :1.163
storage temp. :Inert atmosphere,2-8°C
solubility :≥32.7 mg/mL in DMSO; ≥109.6 mg/mL in EtOH; ≥48.3 mg/mL in H2O with gentle warming
form :Powder
color :Colorless to light yellow
InChI :InChI=1S/C17H23ClO4/c1-2-20-16(19)17(13-22-17)11-5-3-4-6-12-21-15-9-7-14(18)8-10-15/h7-10H,2-6,11-13H2,1H3/t17-/m1/s1
InChIKey :DZLOHEOHWICNIL-QGZVFWFLSA-N
SMILES :O1C[C@]1(CCCCCCOC1=CC=C(Cl)C=C1)C(OCC)=O

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Etomoxir, or 2[6(4-chlorophenoxy)hexyl]oxirane-2-carboxylate, is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) on the outer face of the inner mitochondrial membrane.This prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from the cytosol into the intermembrane space of the mitochondria. This step is essential to the production of ATP from fatty acid oxidation. Etomoxir has also been identified as a direct agonist of PPARα. An off-target effect has been demonstrated at high concentrations of etomoxir on Coenzyme-A (CoA) metabolism.

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