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ChemicalBook >> CAS DataBase List >> RESATORVID

RESATORVID

RESATORVID price.
  • $30 - $25128
  • Product name: RESATORVID
  • CAS: 243984-11-4
  • MF: C15H17ClFNO4S
  • MW: 361.82
  • EINECS:
  • MDL Number:MFCD11046362
  • Synonyms:TAK-242(Resatorvid);1-Cyclohexene-1-carboxylic acid, 6-[[(2-chloro-4-fluorophenyl)aMino]sulfonyl]-, ethyl ester, (6R)-;Resatorvid(TAK-242);Cyclohexene-1-carboxylic acid, 6-[[(2-chloro-4-fluorophenyl)amino]sulfonyl]-, ethyl ester, (6R)-;(R)-ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate;RESATORVID;TAK 242;(6R)-6-[[(2-Chloro-4-fluorophenyl)amino]sulfonyl]-1-cyclohexene-1-carboxylic acid ethyl ester
51 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 5
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 10g
  • ManufacturerAK Scientific
  • Product number4003AH
  • Product descriptionResatorvid
  • Packaging5mg
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA888245
  • Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
  • Packaging1mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA888245
  • Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
  • Packaging5mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA888245
  • Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
  • Packaging10mg
  • Price$114
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA888245
  • Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
  • Packaging25mg
  • Price$216
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA888245
  • Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
  • Packaging50mg
  • Price$345
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA888245
  • Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
  • Packaging100mg
  • Price$543
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA888245
  • Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
  • Packaging250mg
  • Price$985
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA888245
  • Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
  • Packaging1g
  • Price$2645
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA888245
  • Product description(R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+%
  • Packaging10g
  • Price$25128
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000664
  • Product descriptionTAK-242 95.00%
  • Packaging1MG
  • Price$173.25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000664
  • Product descriptionTAK-242 95.00%
  • Packaging5MG
  • Price$816.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000664
  • Product descriptionTAK-242 95.00%
  • Packaging50MG
  • Price$2194.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3850
  • Product descriptionTAK-242
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3850
  • Product descriptionTAK-242
  • Packaging10mM(in 1mL DMSO)
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3850
  • Product descriptionTAK-242
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4003AH Resatorvid 5mg $226 2021-12-16 Buy
Ambeed A888245 (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% 1mg $30 2021-12-16 Buy
Ambeed A888245 (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% 5mg $72 2021-12-16 Buy
Ambeed A888245 (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% 10mg $114 2021-12-16 Buy
Ambeed A888245 (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% 25mg $216 2021-12-16 Buy
Ambeed A888245 (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% 50mg $345 2021-12-16 Buy
Ambeed A888245 (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% 100mg $543 2021-12-16 Buy
Ambeed A888245 (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% 250mg $985 2021-12-16 Buy
Ambeed A888245 (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% 1g $2645 2021-12-16 Buy
Ambeed A888245 (R)-Ethyl6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-enecarboxylate 98+% 10g $25128 2021-12-16 Buy
American Custom Chemicals Corporation INB0000664 TAK-242 95.00% 1MG $173.25 2021-12-16 Buy
American Custom Chemicals Corporation INB0000664 TAK-242 95.00% 5MG $816.75 2021-12-16 Buy
American Custom Chemicals Corporation INB0000664 TAK-242 95.00% 50MG $2194.5 2021-12-16 Buy
ApexBio Technology A3850 TAK-242 5mg $120 2021-12-16 Buy
ApexBio Technology A3850 TAK-242 10mM(in 1mL DMSO) $132 2021-12-16 Buy
ApexBio Technology A3850 TAK-242 10mg $180 2021-12-16 Buy

Properties

Melting point :68-69℃
Boiling point :462.0±55.0 °C(Predicted)
Density :1.39
storage temp. :Sealed in dry,Room Temperature
solubility :insoluble in H2O; ≥100.6 mg/mL in EtOH; ≥18.09 mg/mL in DMSO
form :Solid
pka :7.08±0.40(Predicted)
color :Off-white to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Toll-like receptor 4 (TLR4) is activated by lipopolysaccharide (LPS), with LPS-binding protein, to initiate an innate immune response. Alternatively, hypoxia or ischemia/reperfusion can trigger signaling through TLR4. TAK-242 is a cell-permeable inhibitor of TLR4 signaling, blocking LPS-induced production of NO, TNF-α, IL-6, and IL-1β in macrophages with IC50 values of 1-11 nM. It does not affect signaling through other TLRs. TAK-242 is effective in vivo, suppressing the production of NO, TNF-α, IL-6, and IL-1β in mice treated with LPS when given intravenously. Mechanistically, TAK-242 acts by selectively binding TLR4 and preventing its association with adaptor proteins that are essential for signal transduction. TAK-242 is used to study signaling through TLR4 in a variety of pathologies, including sepsis and ischemia/reperfusion injury.

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