RO-31-8220
- $44 - $1600
- Product name: RO-31-8220
- CAS: 138489-18-6
- MF: C25H23N5O2S
- MW: 457.55
- EINECS:
- MDL Number:MFCD03788207
- Synonyms:RO-31-8220;BISINDOLYLMALEIMIDE IX, METHANESULFONATE;3-[1-[3-(AMIDINOTHIO)PROPYL-1H-INDOL-3-YL]-3-(1-METHYL-1H-INDOL-3-YL)MALEIMIDE;BISINDOLYLMALEIMIDE IX METHANESULPHONATE SALT;BisindolylMaleiMide IX Mesylate;BisindolylMaleiMide IX . Methansulfonate [Ro 31-8220];Carbamimidothioic acid, 3-[3-[2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl ester, methanesulfonate (1:1);Ro31-8220MsOH
35 prices
Selected condition:
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- Arctom
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 500μg
- 1mg
- 5mg
- 10mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0111-M001
- Product descriptionBisindolylmaleimideIX.methanesulfonate ≥98%(NMR)
- Packaging1mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2690AH
- Product descriptionRo31-8220mesylate
- Packaging1mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA350912
- Product descriptionRo31-8220mesylate 98+%
- Packaging1mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA350912
- Product descriptionRo31-8220mesylate 98+%
- Packaging5mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA350912
- Product descriptionRo31-8220mesylate 98+%
- Packaging10mg
- Price$142
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA350912
- Product descriptionRo31-8220mesylate 98+%
- Packaging50mg
- Price$243
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA350912
- Product descriptionRo31-8220mesylate 98+%
- Packaging100mg
- Price$348
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA350912
- Product descriptionRo31-8220mesylate 98+%
- Packaging250mg
- Price$525
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA350912
- Product descriptionRo31-8220mesylate 98+%
- Packaging1g
- Price$1368
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS019955
- Product descriptionRo31-8220mesylate ≥98%
- Packaging1mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS019955
- Product descriptionRo31-8220mesylate ≥98%
- Packaging5mg
- Price$83
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS019955
- Product descriptionRo31-8220mesylate ≥98%
- Packaging10mg
- Price$141
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS019955
- Product descriptionRo31-8220mesylate ≥98%
- Packaging50mg
- Price$241
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS019955
- Product descriptionRo31-8220mesylate ≥98%
- Packaging100mg
- Price$345
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS019955
- Product descriptionRo31-8220mesylate ≥98%
- Packaging250mg
- Price$520
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS019955
- Product descriptionRo31-8220mesylate ≥98%
- Packaging1g
- Price$1354
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | AG-CR1-0111-M001 | BisindolylmaleimideIX.methanesulfonate ≥98%(NMR) | 1mg | $55 | 2021-12-16 | Buy |
AK Scientific | 2690AH | Ro31-8220mesylate | 1mg | $96 | 2021-12-16 | Buy |
Ambeed | A350912 | Ro31-8220mesylate 98+% | 1mg | $50 | 2021-12-16 | Buy |
Ambeed | A350912 | Ro31-8220mesylate 98+% | 5mg | $84 | 2021-12-16 | Buy |
Ambeed | A350912 | Ro31-8220mesylate 98+% | 10mg | $142 | 2021-12-16 | Buy |
Ambeed | A350912 | Ro31-8220mesylate 98+% | 50mg | $243 | 2021-12-16 | Buy |
Ambeed | A350912 | Ro31-8220mesylate 98+% | 100mg | $348 | 2021-12-16 | Buy |
Ambeed | A350912 | Ro31-8220mesylate 98+% | 250mg | $525 | 2021-12-16 | Buy |
Ambeed | A350912 | Ro31-8220mesylate 98+% | 1g | $1368 | 2021-12-16 | Buy |
Arctom | AS019955 | Ro31-8220mesylate ≥98% | 1mg | $50 | 2021-12-16 | Buy |
Arctom | AS019955 | Ro31-8220mesylate ≥98% | 5mg | $83 | 2021-12-16 | Buy |
Arctom | AS019955 | Ro31-8220mesylate ≥98% | 10mg | $141 | 2021-12-16 | Buy |
Arctom | AS019955 | Ro31-8220mesylate ≥98% | 50mg | $241 | 2021-12-16 | Buy |
Arctom | AS019955 | Ro31-8220mesylate ≥98% | 100mg | $345 | 2021-12-16 | Buy |
Arctom | AS019955 | Ro31-8220mesylate ≥98% | 250mg | $520 | 2021-12-16 | Buy |
Arctom | AS019955 | Ro31-8220mesylate ≥98% | 1g | $1354 | 2021-12-16 | Buy |
Properties
storage temp. :2-8°C
solubility :DMSO:52.77(Max Conc. mg/mL);95.31(Max Conc. mM)
DMF:25.0(Max Conc. mg/mL);45.15(Max Conc. mM)
DMF:PBS (pH 7.2) (1:9):0.1(Max Conc. mg/mL);0.18(Max Conc. mM)
Ethanol:2.77(Max Conc. mg/mL);5.0(Max Conc. mM) form :Red solid
color :Red
solubility :DMSO:52.77(Max Conc. mg/mL);95.31(Max Conc. mM)
DMF:25.0(Max Conc. mg/mL);45.15(Max Conc. mM)
DMF:PBS (pH 7.2) (1:9):0.1(Max Conc. mg/mL);0.18(Max Conc. mM)
Ethanol:2.77(Max Conc. mg/mL);5.0(Max Conc. mM) form :Red solid
color :Red
Safety Information
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Description
Bisindolylmaleimide IX (BIM IX) is a potent, cell-permeable inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε, respectively). It is a poor inhibitor of protein kinase A (PKA, IC50 = 0.9 μM) and calcium/calmodulin kinase II (IC50 = 17 μM). BIM IX also inhibits glycogen synthase kinase 3 (IC50 = 6.8 nM).More related product prices
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