ROTTLERIN
|
- $45 - $565
- Product name: ROTTLERIN
- CAS: 82-08-6
- MF: C30H28O8
- MW: 516.54
- EINECS:201-395-4
- MDL Number:MFCD00017361
- Synonyms:3'-[(8-CINNAMOYL-5,7-DIHYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-6-YL)METHYL]-2',4',6'-TRIHYDROXY-5'-METHYLACETOPHENONE;4’,6’-trihydroxy-5’-methyl-methyl)-2 ;acetophenone,3’-((8-cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2h-1-benzopyran-6-yl) ;2-Propen-1-one, 1-[6-[(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl]-3-phenyl-, (2E)-;1-[6-[(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethyl-2h-1-benzopyran-8-yl]-3-phenyl-2-propen-1-one;(E)-1-[6-[(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl]-3-phenyl-2-propen-1-one;Rottlerin,98%;Rottlerin, 98% 10MG
19 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AHH
- ApexBio Technology
- Arctom
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 25mg
- 10mg
- 50
- 50mg
- 100mg
- 0.1g
- 250mg
- 500mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0526-M010
- Product descriptionRottlerin ≥98%(HPLC)
- Packaging10mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-58471
- Product descriptionRottlerin 98%
- Packaging0.1g
- Price$370
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6803
- Product descriptionRottlerin
- Packaging10mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS601734
- Product descriptionRottlerin 97%
- Packaging100mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS601734
- Product descriptionRottlerin 97%
- Packaging250mg
- Price$345
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFR29637
- Product descriptionRottlerin
- Packaging25mg
- Price$72.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFR29637
- Product descriptionRottlerin
- Packaging50mg
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFR29637
- Product descriptionRottlerin
- Packaging100mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFR29637
- Product descriptionRottlerin
- Packaging250mg
- Price$355
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFR29637
- Product descriptionRottlerin
- Packaging500mg
- Price$565
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number12006
- Product descriptionRottlerin ≥90%
- Packaging10mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number12006
- Product descriptionRottlerin ≥90%
- Packaging50mg
- Price$239
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0014823
- Product descriptionRottlerin 97.03%
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0014823
- Product descriptionRottlerin 97.03%
- Packaging25mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number557370
- Product descriptionRottlerin - CAS 82-08-6 - Calbiochem
- Packaging10mg
- Price$144
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number1610
- Product descriptionRottlerin ≥95%(HPLC)
- Packaging10
- Price$95
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CN2-0526-M010 | Rottlerin ≥98%(HPLC) | 10mg | $45 | 2021-12-16 | Buy |
| AHH | MT-58471 | Rottlerin 98% | 0.1g | $370 | 2021-12-16 | Buy |
| ApexBio Technology | B6803 | Rottlerin | 10mg | $68 | 2021-12-16 | Buy |
| Arctom | AS601734 | Rottlerin 97% | 100mg | $175 | 2021-12-16 | Buy |
| Arctom | AS601734 | Rottlerin 97% | 250mg | $345 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FR29637 | Rottlerin | 25mg | $72.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FR29637 | Rottlerin | 50mg | $115 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FR29637 | Rottlerin | 100mg | $180 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FR29637 | Rottlerin | 250mg | $355 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FR29637 | Rottlerin | 500mg | $565 | 2021-12-16 | Buy |
| Cayman Chemical | 12006 | Rottlerin ≥90% | 10mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 12006 | Rottlerin ≥90% | 50mg | $239 | 2024-03-01 | Buy |
| ChemScene | CS-0014823 | Rottlerin 97.03% | 10mg | $60 | 2021-12-16 | Buy |
| ChemScene | CS-0014823 | Rottlerin 97.03% | 25mg | $130 | 2021-12-16 | Buy |
| Sigma-Aldrich | 557370 | Rottlerin - CAS 82-08-6 - Calbiochem | 10mg | $144 | 2024-03-01 | Buy |
| Tocris | 1610 | Rottlerin ≥95%(HPLC) | 10 | $95 | 2021-12-16 | Buy |
Properties
Melting point :200 °C
Boiling point :521.39°C (rough estimate)
Density :1.2051 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 50 mg/ml).
form :Powder
pka :6.92±0.40(Predicted)
color :Orange to brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
LogP :8.660 (est)
CAS DataBase Reference :82-08-6(CAS DataBase Reference)
Boiling point :521.39°C (rough estimate)
Density :1.2051 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 50 mg/ml).
form :Powder
pka :6.92±0.40(Predicted)
color :Orange to brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
LogP :8.660 (est)
CAS DataBase Reference :82-08-6(CAS DataBase Reference)
Safety Information
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Description
Rottlerin was originally identified as an inhibitor of PKCδ (IC50 = 3 μM), but can also inhibit CAM kinase III and a wide range of protein kinases, including PRAK and MAPKAP-K2 (IC50s = 1.9 and 5 μM, respectively). It can act as a direct mitochondrial uncoupler, and stimulates autophagy by targeting a signaling cascade upstream of mTORC1. Rottlerin has also been shown to have neuroprotective effects in an MPTP animal model of Parkinson’s disease.More related product prices
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