Rhein
|
61 prices
Selected condition：
Brand
- AK Scientific
- Alfa Aesar
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Chemtos
- Crysdot
- DC Chemicals
- JR MediChem
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 50
- 1mg
- 10
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 400mg
- 500mg
- 0.5g
- 1g
- 5g
- 10g
- 25g
- 50g
- 100g
- ManufacturerAK Scientific
- Product numberC432
- Product descriptionRhein
- Packaging1g
- Price$364
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberH60902
- Product descriptionRhein, 97%
- Packaging250mg
- Price$154.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberH60902
- Product descriptionRhein, 97%
- Packaging1g
- Price$456
- Updated2024-03-01
- Buy
- ManufacturerAmbeed
- Product numberA105483
- Product description4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylicacid 98+%
- Packaging25mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105483
- Product description4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylicacid 98+%
- Packaging100mg
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105483
- Product description4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylicacid 98+%
- Packaging250mg
- Price$9
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105483
- Product description4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylicacid 98+%
- Packaging1g
- Price$19
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105483
- Product description4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylicacid 98+%
- Packaging5g
- Price$58
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105483
- Product description4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylicacid 98+%
- Packaging25g
- Price$188
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105483
- Product description4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylicacid 98+%
- Packaging100g
- Price$548
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0026593
- Product descriptionRHEIN 95.00%
- Packaging100MG
- Price$739.2
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0026593
- Product descriptionRHEIN 95.00%
- Packaging1G
- Price$1871.1
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN1810
- Product descriptionRhein
- Packaging100mg
- Price$53
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN1810
- Product descriptionRhein
- Packaging200mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN1810
- Product descriptionRhein
- Packaging500mg
- Price$152
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN99157
- Product descriptionRhein ≥98%
- Packaging20mg
- Price$40
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | C432 | Rhein | 1g | $364 | 2021-12-16 | Buy |
| Alfa Aesar | H60902 | Rhein, 97% | 250mg | $154.65 | 2024-03-01 | Buy |
| Alfa Aesar | H60902 | Rhein, 97% | 1g | $456 | 2024-03-01 | Buy |
| Ambeed | A105483 | 4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylicacid 98+% | 25mg | $5 | 2021-12-16 | Buy |
| Ambeed | A105483 | 4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylicacid 98+% | 100mg | $6 | 2021-12-16 | Buy |
| Ambeed | A105483 | 4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylicacid 98+% | 250mg | $9 | 2021-12-16 | Buy |
| Ambeed | A105483 | 4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylicacid 98+% | 1g | $19 | 2021-12-16 | Buy |
| Ambeed | A105483 | 4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylicacid 98+% | 5g | $58 | 2021-12-16 | Buy |
| Ambeed | A105483 | 4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylicacid 98+% | 25g | $188 | 2021-12-16 | Buy |
| Ambeed | A105483 | 4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylicacid 98+% | 100g | $548 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0026593 | RHEIN 95.00% | 100MG | $739.2 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0026593 | RHEIN 95.00% | 1G | $1871.1 | 2021-12-16 | Buy |
| ApexBio Technology | N1810 | Rhein | 100mg | $53 | 2021-12-16 | Buy |
| ApexBio Technology | N1810 | Rhein | 200mg | $84 | 2021-12-16 | Buy |
| ApexBio Technology | N1810 | Rhein | 500mg | $152 | 2021-12-16 | Buy |
| Arctom | CFN99157 | Rhein ≥98% | 20mg | $40 | 2021-12-16 | Buy |
Properties
Melting point :≥300 °C (lit.)
Boiling point :346.72°C (rough estimate)
Density :1.3269 (rough estimate)
refractive index :1.4413 (estimate)
storage temp. :2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :3.17±0.20(Predicted)
form :Solid
color :Yellow to Dark Orange
Water Solubility :<0.1 g/100 mL at 17 ºC
λmax :432nm(MeOH)(lit.)
Merck :14,8176
BRN :2222155
Stability :Hygroscopic
InChIKey :FCDLCPWAQCPTKC-UHFFFAOYSA-N
LogP :4.290 (est)
CAS DataBase Reference :478-43-3(CAS DataBase Reference)
EPA Substance Registry System :2-Anthracenecarboxylic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo- (478-43-3)
Boiling point :346.72°C (rough estimate)
Density :1.3269 (rough estimate)
refractive index :1.4413 (estimate)
storage temp. :2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :3.17±0.20(Predicted)
form :Solid
color :Yellow to Dark Orange
Water Solubility :<0.1 g/100 mL at 17 ºC
λmax :432nm(MeOH)(lit.)
Merck :14,8176
BRN :2222155
Stability :Hygroscopic
InChIKey :FCDLCPWAQCPTKC-UHFFFAOYSA-N
LogP :4.290 (est)
CAS DataBase Reference :478-43-3(CAS DataBase Reference)
EPA Substance Registry System :2-Anthracenecarboxylic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo- (478-43-3)
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Rhein is an anti-inflammatory anthraquinone found in rhubarb and is the bioactive derivative of its prodrug diacerein . At 10 μM, rhein inhibits IL-1β signaling, suppressing signaling through NF-κB, and reduces the expression of the matrix metalloproteases MMP-1 and MMP-13. It inhibits IKKβ (IC50 = 11.8 μM), decreasing iNOS and IL-6 expression in LPS-stimulated macrophages but paradoxically increasing TNF-α, IL-1β, and HMBG1 expression. Rhein shows efficacy against pancreatic fibrosis, chronic pancreatitis, and hyperglycemia-induced pancreatic β-cell apoptosis. It also inhibits angiogenesis of breast cancer cells under normoxic and hypoxic conditions.More related product prices
Mitoxantrone Citric acid Folic acid ACETIC ACID Phosphorus 1,8-Dihydroxyanthraquinone Mitoxantrone hydrochloride 3347-22-6 Diacerein Emodin Chrysophanic acid 613-08-1 RheinRelated product price
- Mitoxantrone
$42-1732.5 - Citric acid
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$5-1269.63
Suppliers and manufacturers
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
Nanjing ChemLin Chemical Industry Co., Ltd.
Shanghai Zheyan Biotech Co., Ltd.
Shaanxi Yikanglong Biotechnology Co., Ltd.
Chengdu Biopurify Phytochemicals Ltd.
Hubei Jusheng Technology Co.,Ltd.
Xiamen AmoyChem Co., Ltd
