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ChemicalBook >> CAS DataBase List >> SB 415286

SB 415286

SB 415286 price.
  • $21 - $7030
  • Product name: SB 415286
  • CAS: 264218-23-7
  • MF: C16H10ClN3O5
  • MW: 359.72
  • EINECS:
  • MDL Number:MFCD04039789
  • Synonyms:1H-Pyrrole-2,5-dione, 3-[(3-chloro-4-hydroxyphenyl)aMino]-4-(2-nitrophenyl)-;SB 415286;3-[(3-CHLORO-4-HYDROXYPHENYL)AMINO]-4-(2-NITROPHENYL)-1H-PYRROLE-2,5-DIONE;3-[(3-CHLORO-4-HYDROXYPHENYL)AMINO]-4-(2-NITROPHENYL)-1H-PYRROL-2,5-DIONE;7-L-Alanine-cyclosporin A;SB 415286 USP/EP/BP;SB-41528;CS-228
32 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 500μg
  • 10mM(in 1mL DMSO)
  • 10
  • 1MG
  • 50
  • 2.5mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3658-M005
  • Product descriptionSB 415286 ≥97%
  • Packaging5mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3658-M025
  • Product descriptionSB 415286 ≥97%
  • Packaging25mg
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX7617
  • Product descriptionSB 415286
  • Packaging50mg
  • Price$674
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA984794
  • Product descriptionSB 415286 98+%
  • Packaging10mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA984794
  • Product descriptionSB 415286 98+%
  • Packaging50mg
  • Price$365
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA984794
  • Product descriptionSB 415286 98+%
  • Packaging1g
  • Price$2443
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000228
  • Product descriptionSB 415286 95.00%
  • Packaging1MG
  • Price$154.35
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000228
  • Product descriptionSB 415286 95.00%
  • Packaging10MG
  • Price$885.31
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8241
  • Product descriptionSB 415286
  • Packaging10mM(in 1mL DMSO)
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8241
  • Product descriptionSB 415286
  • Packaging50mg
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60442
  • Product descriptionSB 415286 ≥98%
  • Packaging10mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010247
  • Product descriptionSB 415286 ≥98%
  • Packaging500μg
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010247
  • Product descriptionSB 415286 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010247
  • Product descriptionSB 415286 ≥98%
  • Packaging5mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10010247
  • Product descriptionSB 415286 ≥98%
  • Packaging10mg
  • Price$142
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM198879
  • Product description3-(3-Chloro-4-hydroxyphenylamino)-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione 98%
  • Packaging50mg
  • Price$364
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3658-M005 SB 415286 ≥97% 5mg $95 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3658-M025 SB 415286 ≥97% 25mg $380 2021-12-16 Buy
AK Scientific X7617 SB 415286 50mg $674 2021-12-16 Buy
Ambeed A984794 SB 415286 98+% 10mg $144 2021-12-16 Buy
Ambeed A984794 SB 415286 98+% 50mg $365 2021-12-16 Buy
Ambeed A984794 SB 415286 98+% 1g $2443 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000228 SB 415286 95.00% 1MG $154.35 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000228 SB 415286 95.00% 10MG $885.31 2021-12-16 Buy
ApexBio Technology A8241 SB 415286 10mM(in 1mL DMSO) $110 2021-12-16 Buy
ApexBio Technology A8241 SB 415286 50mg $330 2021-12-16 Buy
Arctom CFN60442 SB 415286 ≥98% 10mg $218 2021-12-16 Buy
Cayman Chemical 10010247 SB 415286 ≥98% 500μg $21 2021-12-16 Buy
Cayman Chemical 10010247 SB 415286 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 10010247 SB 415286 ≥98% 5mg $116 2024-03-01 Buy
Cayman Chemical 10010247 SB 415286 ≥98% 10mg $142 2024-03-01 Buy
Chemenu CM198879 3-(3-Chloro-4-hydroxyphenylamino)-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione 98% 50mg $364 2021-12-16 Buy

Properties

Boiling point :595.8±50.0 °C(Predicted)
Density :1.647
storage temp. :-20°C
solubility :DMSO: 16 mg/mL
form :Yellow Solid.
pka :6.81±0.60(Predicted)
color :yellow to orange

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SB-415286 is an ATP-competitive inhibitor of GSK3α (Glycogen Synthase Kinase 3α) with a Ki value of 31 nM. SB-415286 displays similar potency for GSK-3β. Alternate studies suggest that SB-415286 stabilizes β-catenin, which in turn leads to inhibition of coxsackievirus-induced cell death. SB-415286 is an inhibitor of GSK-3 β.

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