Welcome to chemicalbook!
China English Japan Germany
400-158-6606
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structure Search
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook My chemicalbook

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> 2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride

2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride

2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride price.
  • $33 - $1348
  • Product name: 2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride
  • CAS: 694433-59-5
  • MF: C20H21N3O2
  • MW: 335.4
  • EINECS:
  • MDL Number:MFCD20926329
  • Synonyms:2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride;SB-505124 hydrate hydrochloride;2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-iMidazol-4-yl)-6-Methylpyridine;2-[4-(1,3-Benzodioxol-5-yl)-2-(1,1- diMethylethyl)-1H-iMidazol-5-yl]-6-Methyl-pyridine;2-[4-(1,3-Benzodioxol-5-yl)-2-(tert-butyl)-1H-imidazol-5-yl]-6-methylpyridine;SB-505124 hydrochloride hydrate;2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine;2-[4-(1,3-Benzodioxol-5-yl)-2-(tert-butyl)-1H-imidazol-5-yl]-6-methylpyridine SB505124
Price39 Properties Safety Information Description
39 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2707AH
  • Product descriptionSB-505124
  • Packaging50mg
  • Price$419
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA114347
  • Product descriptionSB-505124 98+%
  • Packaging1mg
  • Price$33
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA114347
  • Product descriptionSB-505124 98+%
  • Packaging5mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA114347
  • Product descriptionSB-505124 98+%
  • Packaging10mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA114347
  • Product descriptionSB-505124 98+%
  • Packaging50mg
  • Price$266
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA114347
  • Product descriptionSB-505124 98+%
  • Packaging100mg
  • Price$395
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA114347
  • Product descriptionSB-505124 98+%
  • Packaging250mg
  • Price$537
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA114347
  • Product descriptionSB-505124 98+%
  • Packaging1g
  • Price$1348
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007582
  • Product descriptionSB-505124 HYDROCHLORIDE HYDRATE 95.00%
  • Packaging5MG
  • Price$756.58
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007582
  • Product descriptionSB-505124 HYDROCHLORIDE HYDRATE 95.00%
  • Packaging25MG
  • Price$1226.1
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS436193
  • Product descriptionSB-505124 ≥98%
  • Packaging1mg
  • Price$33
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS436193
  • Product descriptionSB-505124 ≥98%
  • Packaging5mg
  • Price$64
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS436193
  • Product descriptionSB-505124 ≥98%
  • Packaging10mg
  • Price$109
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60366
  • Product descriptionSB505124 ≥98%
  • Packaging5mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS436193
  • Product descriptionSB-505124 ≥98%
  • Packaging50mg
  • Price$263
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS436193
  • Product descriptionSB-505124 ≥98%
  • Packaging100mg
  • Price$391
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2707AH SB-505124 50mg $419 2021-12-16 Buy
Ambeed A114347 SB-505124 98+% 1mg $33 2021-12-16 Buy
Ambeed A114347 SB-505124 98+% 5mg $65 2021-12-16 Buy
Ambeed A114347 SB-505124 98+% 10mg $110 2021-12-16 Buy
Ambeed A114347 SB-505124 98+% 50mg $266 2021-12-16 Buy
Ambeed A114347 SB-505124 98+% 100mg $395 2021-12-16 Buy
Ambeed A114347 SB-505124 98+% 250mg $537 2021-12-16 Buy
Ambeed A114347 SB-505124 98+% 1g $1348 2021-12-16 Buy
American Custom Chemicals Corporation API0007582 SB-505124 HYDROCHLORIDE HYDRATE 95.00% 5MG $756.58 2021-12-16 Buy
American Custom Chemicals Corporation API0007582 SB-505124 HYDROCHLORIDE HYDRATE 95.00% 25MG $1226.1 2021-12-16 Buy
Arctom AS436193 SB-505124 ≥98% 1mg $33 2021-12-16 Buy
Arctom AS436193 SB-505124 ≥98% 5mg $64 2021-12-16 Buy
Arctom AS436193 SB-505124 ≥98% 10mg $109 2021-12-16 Buy
Arctom CFN60366 SB505124 ≥98% 5mg $138 2021-12-16 Buy
Arctom AS436193 SB-505124 ≥98% 50mg $263 2021-12-16 Buy
Arctom AS436193 SB-505124 ≥98% 100mg $391 2021-12-16 Buy
Next Last

Properties

Melting point :168 °C
Boiling point :509.7±50.0 °C(Predicted)
Density :1.202
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: >10mg/mL
pka :11.26±0.10(Predicted)
form :powder
color :yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SB-505124 inhibits the TGF-β1 receptor serine/threonine kinase ALK5 with an IC50 value of 47 nM. Though it is a less potent antagonist of ALK4 (IC50 = 129 nM) and ALK7, SB-505124 selectively and concentration-dependently inhibits ALK4-, ALK5-, and ALK7-dependent activation of downstream SMAD2 and SMAD3 and TGF-β–induced MAP kinase pathway components without altering ALK1-3 or ALK6-induced SMAD signaling. In an assay determining in vitro phosphorylation of SMAD3, SB-505124 is more potent than SB-431452 with IC50 values of 47 versus 94 nM, respectively.

More related product prices

474960-44-6 864741-95-7 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4- carboxamide LY2109761 MK-2206 2HCl Ispinesib SB 203580 SB-705498 472981-92-3 356559-20-1 405554-55-4 SB 431542 SB 202190 SB 415286 SB 242084 (hydrochloride) Olaparib LY 2157299 252917-06-9 MMP-2/MMP-9 INHIBITOR IV Sb-742457

Related product price

Suppliers and manufacturers

career henan chemical co
2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride
$1.00 /1KG
2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride CAS:694433-59-5
ATK CHEMICAL COMPANY LIMITED
Biochempartner
Hubei xin bonus chemical co. LTD
TargetMol Chemicals Inc.
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Hangzhou MolCore BioPharmatech Co.,Ltd.
ShenZhen Trendseen Biological Technology Co.,Ltd.
LEAPCHEM CO., LTD.