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ChemicalBook >> CAS DataBase List >> Scutellarin

Scutellarin

Scutellarin price.
  • $31 - $1647
  • Product name: Scutellarin
  • CAS: 27740-01-8
  • MF: C21H18O12
  • MW: 462.36
  • EINECS:1806241-263-5
  • MDL Number:MFCD01861503
  • Synonyms:SCUTELLARIN, 98+% BY HPLC;(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl;β-D-Glucopyranosiduronicacid,5,6-dihydroxy-2-;4',5,6-Trihydroxy-7-[(β-D-glucopyranuronosyl)oxy]flavone;4',5,6-Trihydroxyflavon-7-yl β-D-glucopyranosiduronic acid;5,6-Dihydroxy-4-oxo-2-(4-hydroxyphenyl)-4H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid;Scutellarein 4'-methyl ether 7-glucuronide;Scutellarein 7-glucuronide
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  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
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  • AvaChem
  • Biorbyt Ltd
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  • Cayman Chemical
  • Chemenu
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  • DC Chemicals
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  • Sigma-Aldrich
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Package
  • 5mg
  • 10mg
  • 20mg
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  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberJ96074
  • Product descriptionScutellarin
  • Packaging5mg
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA126805
  • Product description(2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylicacid 97%
  • Packaging1g
  • Price$935
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA126805
  • Product description(2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylicacid 97%
  • Packaging100mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA126805
  • Product description(2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylicacid 97%
  • Packaging50mg
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA126805
  • Product description(2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylicacid 97%
  • Packaging25mg
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA126805
  • Product description(2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylicacid 97%
  • Packaging10mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA126805
  • Product description(2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylicacid 97%
  • Packaging5mg
  • Price$31
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPXT0001154
  • Product descriptionSCUTELLARIN 98.00%
  • Packaging10MG
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPXT0001154
  • Product descriptionSCUTELLARIN 98.00%
  • Packaging100MG
  • Price$1593.9
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberN1753
  • Product descriptionScutellarin
  • Packaging20mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS020319
  • Product descriptionScutellarin 97%
  • Packaging5mg
  • Price$31
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberCFN99112
  • Product descriptionScutellarin
  • Packaging20mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS020319
  • Product descriptionScutellarin 97%
  • Packaging50mg
  • Price$68
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberSY068753
  • Product descriptionScutellarin,98%
  • Packaging10mg
  • Price$85.91
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS020319
  • Product descriptionScutellarin 97%
  • Packaging100mg
  • Price$109
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1880
  • Product descriptionScutellarin
  • Packaging10mg
  • Price$39
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J96074 Scutellarin 5mg $34 2021-12-16 Buy
Ambeed A126805 (2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylicacid 97% 1g $935 2021-12-16 Buy
Ambeed A126805 (2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylicacid 97% 100mg $110 2021-12-16 Buy
Ambeed A126805 (2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylicacid 97% 50mg $69 2021-12-16 Buy
Ambeed A126805 (2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylicacid 97% 25mg $53 2021-12-16 Buy
Ambeed A126805 (2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylicacid 97% 10mg $40 2021-12-16 Buy
Ambeed A126805 (2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylicacid 97% 5mg $31 2021-12-16 Buy
American Custom Chemicals Corporation PXT0001154 SCUTELLARIN 98.00% 10MG $704.55 2021-12-16 Buy
American Custom Chemicals Corporation PXT0001154 SCUTELLARIN 98.00% 100MG $1593.9 2021-12-16 Buy
ApexBio Technology N1753 Scutellarin 20mg $60 2021-12-16 Buy
Arctom AS020319 Scutellarin 97% 5mg $31 2021-12-16 Buy
Arctom CFN99112 Scutellarin 20mg $50 2021-12-16 Buy
Arctom AS020319 Scutellarin 97% 50mg $68 2021-12-16 Buy
Arctom SY068753 Scutellarin,98% 10mg $85.91 2021-12-16 Buy
Arctom AS020319 Scutellarin 97% 100mg $109 2021-12-16 Buy
AvaChem 1880 Scutellarin 10mg $39 2021-12-16 Buy

Properties

Melting point :300~301℃
Boiling point :891.6±65.0 °C(Predicted)
Density :1.810±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO (Slightly), Methanol (Very Slightly, Sonicated)
pka :2.72±0.70(Predicted)
form :Solid
color :Light Yellow to Yellow
BRN :71779
CAS DataBase Reference :27740-01-8(CAS DataBase Reference)

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Description

Scutellarin is a flavone that has been found in S. barbata and has diverse biological activities, including anticancer, lipid lowering, antioxidative, and neurocognitive properties. It inhibits proliferation of PC-9 and H1975 non-small cell lung cancer (NSCLC) cells in a concentration-dependent manner and induces apoptosis and autophagy when used at a concentration of 160 μM, effects that can be blocked by the autophagy inhibitor HCQ . Scutellarin (30 and 60 mg/kg per day) reduces tumor growth in an H1975 mouse xenograft model. It decreases serum total cholesterol and LDL-cholesterol and increases HDL-cholesterol in a high-fat diet-induced mouse model of non-alcoholic fatty liver disease (NAFLD) when administered at doses of 25 and 50 mg/kg. It decreases hepatic malondialdehyde (MDA), glutamic-oxalacetic transaminase (GOT), and glutamic-pyruvic transaminase (GPT) activity, increases catalase (CAT) and total antioxidative capacity (T-AOC) activity, and increases the hepatic expression of PPARγ, PGC-1α, and Nrf2 in the same model. Scutellarin (5, 25, and 50 mg/kg per day) also prevents deficits in spatial and novel object memory in rats in the Y maze and novel object recognition test, respectively.

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