TENOVIN-1
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- $28 - $1802
- Product name: TENOVIN-1
- CAS: 380315-80-0
- MF: C20H23N3O2S
- MW: 369.48
- EINECS:200-256-5
- MDL Number:MFCD02914760
- Synonyms:TENOVIN-1;N-[[[4-(Acetylamino)phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide;N-[(4-acetaMidophenyl)carbaMothioyl]-4-tert-butylbenzaMide;Benzamide, N-[[[4-(acetylamino)phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)-;N-[[[4-(Acetylamino)phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide Tenovin 1;Tenovin 1 N-[[[4-(Acetylamino)phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide;Tenovin-1, >=98%;TENOVIN-1;TENOVIN 1
27 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Tocris
- TRC
- Usbiological
Package
- 10
- 1unit
- 5mg
- 10mg
- 50mg
- 50
- 25mg
- 250mg
- 10mM(in 1mL DMSO)
- 100mg
- 1g
- ManufacturerAK Scientific
- Product numberSYN5421
- Product descriptionTenovin-1
- Packaging10mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001626
- Product descriptionN-[[[4-(ACETYLAMINO)PHENYL]AMINO]THIOXOMETHYL-4-(1,1-DIMETHYLETHYL)]-BENZAMIDE 95.00%
- Packaging10MG
- Price$208.95
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4203
- Product descriptionTenovin-1
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4203
- Product descriptionTenovin-1
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4203
- Product descriptionTenovin-1
- Packaging25mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4203
- Product descriptionTenovin-1
- Packaging50mg
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4203
- Product descriptionTenovin-1
- Packaging100mg
- Price$330
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2008
- Product descriptionTenovin1 99%
- Packaging50mg
- Price$231
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146079
- Product descriptionTenovin-1 >98%
- Packaging100mg
- Price$606.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146079
- Product descriptionTenovin-1 >98%
- Packaging250mg
- Price$912.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146079
- Product descriptionTenovin-1 >98%
- Packaging1g
- Price$1802
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13085
- Product descriptionTenovin-1 ≥98%
- Packaging5mg
- Price$33
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13085
- Product descriptionTenovin-1 ≥98%
- Packaging10mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13085
- Product descriptionTenovin-1 ≥98%
- Packaging50mg
- Price$254
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13085
- Product descriptionTenovin-1 ≥98%
- Packaging100mg
- Price$443
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-1512
- Product descriptionTenovin-1 99.88%
- Packaging50mg
- Price$136
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5421 | Tenovin-1 | 10mg | $104 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001626 | N-[[[4-(ACETYLAMINO)PHENYL]AMINO]THIOXOMETHYL-4-(1,1-DIMETHYLETHYL)]-BENZAMIDE 95.00% | 10MG | $208.95 | 2021-12-16 | Buy |
| ApexBio Technology | A4203 | Tenovin-1 | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A4203 | Tenovin-1 | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
| ApexBio Technology | A4203 | Tenovin-1 | 25mg | $90 | 2021-12-16 | Buy |
| ApexBio Technology | A4203 | Tenovin-1 | 50mg | $170 | 2021-12-16 | Buy |
| ApexBio Technology | A4203 | Tenovin-1 | 100mg | $330 | 2021-12-16 | Buy |
| Axon Medchem | Axon2008 | Tenovin1 99% | 50mg | $231 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146079 | Tenovin-1 >98% | 100mg | $606.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146079 | Tenovin-1 >98% | 250mg | $912.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146079 | Tenovin-1 >98% | 1g | $1802 | 2021-12-16 | Buy |
| Cayman Chemical | 13085 | Tenovin-1 ≥98% | 5mg | $33 | 2024-03-01 | Buy |
| Cayman Chemical | 13085 | Tenovin-1 ≥98% | 10mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 13085 | Tenovin-1 ≥98% | 50mg | $254 | 2024-03-01 | Buy |
| Cayman Chemical | 13085 | Tenovin-1 ≥98% | 100mg | $443 | 2024-03-01 | Buy |
| ChemScene | CS-1512 | Tenovin-1 99.88% | 50mg | $136 | 2021-12-16 | Buy |
Properties
Melting point :>180°C (Subl.)
Density :1.238±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO (10 mg/ml with warming)
form :solid
pka :9.09±0.70(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Density :1.238±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO (10 mg/ml with warming)
form :solid
pka :9.09±0.70(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
Tenovin-1 is a small molecule activator of p53 transcriptional activity. At 10 μM, it elevates p53 expression in MCF-7 cells within two hours of treatment and longer-term exposure significantly decreases the growth of BL2 Burkitt’s lymphoma and ARN8 melanoma cells. Functioning upstream of p53, tenovin-1 acts by inhibiting the deacetylase activity of purified human SIRT1 and SIRT2, members of NAD+-dependent class III histone deacetylases that belong to the sirtuin family. While tenovin-1 demonstrates low genotoxicity, the compound has poor water solubility, which limits its uses in vivo.Related product price
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