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ChemicalBook >> CAS DataBase List >> Tenovin-6

Tenovin-6

Tenovin-6 price.
  • $60 - $2293
  • Product name: Tenovin-6
  • CAS: 1011557-82-6
  • MF: C25H34N4O2S
  • MW: 454.63
  • EINECS:200-256-5
  • MDL Number:MFCD11976906
  • Synonyms:Tenovin-6;4-TERT-BUTYL-N-(4-(5-(DIMETHYLAMINO)PENTANAMIDO)PHENYLCARBAMOTHIOYL)BENZAMIDE HYDROCHLORIDE;N-[[[4-[[5-(Dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide;Benzamide, N-[[[4-[[5-(dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)-;N-[[[4-[[5-(Dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide Tenovin-6;Tenovin-6, >=98%;4-(tert-Butyl)-N-((4-(4-(dimethylamino)butanamido)phenyl)carbAmothioyl)benzamide;Tenovin 6 - Tnv 6
29 prices
Selected condition:
Brand
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 10mM(in 1mL DMSO)
  • 100mg
  • 250mg
  • 1g
  • 1000mg
  • ManufacturerAmbeed
  • Product numberA693915
  • Product description4-(tert-Butyl)-N-((4-(5-(dimethylamino)pentanamido)phenyl)carbamothioyl)benzamide 98+%
  • Packaging5mg
  • Price$211
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA693915
  • Product description4-(tert-Butyl)-N-((4-(5-(dimethylamino)pentanamido)phenyl)carbamothioyl)benzamide 98+%
  • Packaging10mg
  • Price$343
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA693915
  • Product description4-(tert-Butyl)-N-((4-(5-(dimethylamino)pentanamido)phenyl)carbamothioyl)benzamide 98+%
  • Packaging25mg
  • Price$569
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004725
  • Product descriptionN-(((4-((5-(DIMETHYLAMINO)-1-OXOPENTYL)AMINO)PHENYL)AMINO)THIOXOMETHYL)-4-(1,1-DIMETHYLETHYL)-BENZAMIDE 95.00%
  • Packaging5MG
  • Price$501.23
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8302
  • Product descriptionTenovin-6
  • Packaging1mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8302
  • Product descriptionTenovin-6
  • Packaging5mg
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8302
  • Product descriptionTenovin-6
  • Packaging10mM(in 1mL DMSO)
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8302
  • Product descriptionTenovin-6
  • Packaging10mg
  • Price$360
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8302
  • Product descriptionTenovin-6
  • Packaging25mg
  • Price$710
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2249
  • Product descriptionTenovin6-Tnv6 99%
  • Packaging25mg
  • Price$401.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181161
  • Product descriptionTenovin-6 >98%
  • Packaging100mg
  • Price$578
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb181161
  • Product descriptionTenovin-6 >98%
  • Packaging250mg
  • Price$1133.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181161
  • Product descriptionTenovin-6 >98%
  • Packaging1000mg
  • Price$2245.7
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13086
  • Product descriptionTenovin-6 ≥95%
  • Packaging1mg
  • Price$131
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13086
  • Product descriptionTenovin-6 ≥95%
  • Packaging5mg
  • Price$590
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13086
  • Product descriptionTenovin-6 ≥95%
  • Packaging10mg
  • Price$1048
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A693915 4-(tert-Butyl)-N-((4-(5-(dimethylamino)pentanamido)phenyl)carbamothioyl)benzamide 98+% 5mg $211 2021-12-16 Buy
Ambeed A693915 4-(tert-Butyl)-N-((4-(5-(dimethylamino)pentanamido)phenyl)carbamothioyl)benzamide 98+% 10mg $343 2021-12-16 Buy
Ambeed A693915 4-(tert-Butyl)-N-((4-(5-(dimethylamino)pentanamido)phenyl)carbamothioyl)benzamide 98+% 25mg $569 2021-12-16 Buy
American Custom Chemicals Corporation INB0004725 N-(((4-((5-(DIMETHYLAMINO)-1-OXOPENTYL)AMINO)PHENYL)AMINO)THIOXOMETHYL)-4-(1,1-DIMETHYLETHYL)-BENZAMIDE 95.00% 5MG $501.23 2021-12-16 Buy
ApexBio Technology A8302 Tenovin-6 1mg $80 2021-12-16 Buy
ApexBio Technology A8302 Tenovin-6 5mg $230 2021-12-16 Buy
ApexBio Technology A8302 Tenovin-6 10mM(in 1mL DMSO) $230 2021-12-16 Buy
ApexBio Technology A8302 Tenovin-6 10mg $360 2021-12-16 Buy
ApexBio Technology A8302 Tenovin-6 25mg $710 2021-12-16 Buy
Axon Medchem Axon2249 Tenovin6-Tnv6 99% 25mg $401.5 2021-12-16 Buy
Biorbyt Ltd orb181161 Tenovin-6 >98% 100mg $578 2021-12-16 Buy
Biorbyt Ltd orb181161 Tenovin-6 >98% 250mg $1133.9 2021-12-16 Buy
Biorbyt Ltd orb181161 Tenovin-6 >98% 1000mg $2245.7 2021-12-16 Buy
Cayman Chemical 13086 Tenovin-6 ≥95% 1mg $131 2021-12-16 Buy
Cayman Chemical 13086 Tenovin-6 ≥95% 5mg $590 2021-12-16 Buy
Cayman Chemical 13086 Tenovin-6 ≥95% 10mg $1048 2021-12-16 Buy

Properties

Density :1.171±0.06 g/cm3(Predicted)
storage temp. :Store at -20° C
solubility :≥22.75 mg/mL in DMSO; insoluble in H2O; ≥2.62 mg/mL in EtOH with ultrasonic
form :solid
pka :9.11±0.70(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The tumor suppressor function of p53 hinges on its ability to function as a transcription factor. Tenovin-6 is an analog of tenovin-1, a small molecule activator of p53 transcriptional activity. At 10 μM, this compound is slightly more effective than tenovin-1 at elevating p53 activity in MCF-7 cells and reduces growth of ARN8 melanoma xenograft tumors in SCID mice at a dose of 50 mg/kg. Tenovin-6 inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 in vitro with IC50 values of 21, 10, and 67 μM, respectively.

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