Vildagliptin
|
- $5 - $2766.23
- Product name: Vildagliptin
- CAS: 274901-16-5
- MF: C17H25N3O2
- MW: 303.4
- EINECS:630-410-0
- MDL Number:MFCD08275142
- Synonyms:Vidagliptin (see vildagliptin);Vildagliptin;1-[2-(3-HydroxyadaMant-1-ylaMino)acetyl]pyrrolidine-2(S)-carbonitrile;(S)-1-[2-((5S,7S)-3-hydroxy-adaMantan-1-ylaMino)-acetyl]-pyrrolidine-2-carbonitrile;NVP-LAF 237;ZoMelis;Vildagliptin API;Vildagliptin (NVP-LAF 237)
43 prices
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Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemcia Scientific
- ChemScene
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 10mM(in 1mL DMSO)
- 10mg
- 25mg
- 50mg
- 100mg
- 250MG
- 500mg
- 1g
- 5g
- 10g
- 25g
- 100g
- 500g
- ManufacturerAK Scientific
- Product numberJ50296
- Product descriptionVildagliptin
- Packaging1g
- Price$137
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA403832
- Product description(2S)-1-((3-Hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile 98+%
- Packaging100mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA403832
- Product description(2S)-1-((3-Hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile 98+%
- Packaging1g
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA403832
- Product description(2S)-1-((3-Hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile 98+%
- Packaging5g
- Price$29
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA403832
- Product description(2S)-1-((3-Hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile 98+%
- Packaging10g
- Price$52
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA403832
- Product description(2S)-1-((3-Hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile 98+%
- Packaging25g
- Price$101
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA403832
- Product description(2S)-1-((3-Hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile 98+%
- Packaging100g
- Price$294
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA403832
- Product description(2S)-1-((3-Hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile 98+%
- Packaging500g
- Price$1110
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004851
- Product descriptionVILDAGLIPTIN 95.00%
- Packaging10G
- Price$2766.23
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004851
- Product descriptionVILDAGLIPTIN 95.00%
- Packaging5G
- Price$1899.98
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004851
- Product descriptionVILDAGLIPTIN 95.00%
- Packaging1G
- Price$1149.23
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004851
- Product descriptionVILDAGLIPTIN 95.00%
- Packaging250MG
- Price$492.45
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4037
- Product descriptionVildagliptin(LAF-237)
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4037
- Product descriptionVildagliptin(LAF-237)
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4037
- Product descriptionVildagliptin(LAF-237)
- Packaging25mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4037
- Product descriptionVildagliptin(LAF-237)
- Packaging50mg
- Price$150
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | J50296 | Vildagliptin | 1g | $137 | 2021-12-16 | Buy |
| Ambeed | A403832 | (2S)-1-((3-Hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile 98+% | 100mg | $5 | 2021-12-16 | Buy |
| Ambeed | A403832 | (2S)-1-((3-Hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile 98+% | 1g | $10 | 2021-12-16 | Buy |
| Ambeed | A403832 | (2S)-1-((3-Hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile 98+% | 5g | $29 | 2021-12-16 | Buy |
| Ambeed | A403832 | (2S)-1-((3-Hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile 98+% | 10g | $52 | 2021-12-16 | Buy |
| Ambeed | A403832 | (2S)-1-((3-Hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile 98+% | 25g | $101 | 2021-12-16 | Buy |
| Ambeed | A403832 | (2S)-1-((3-Hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile 98+% | 100g | $294 | 2021-12-16 | Buy |
| Ambeed | A403832 | (2S)-1-((3-Hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile 98+% | 500g | $1110 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004851 | VILDAGLIPTIN 95.00% | 10G | $2766.23 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004851 | VILDAGLIPTIN 95.00% | 5G | $1899.98 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004851 | VILDAGLIPTIN 95.00% | 1G | $1149.23 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004851 | VILDAGLIPTIN 95.00% | 250MG | $492.45 | 2021-12-16 | Buy |
| ApexBio Technology | A4037 | Vildagliptin(LAF-237) | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A4037 | Vildagliptin(LAF-237) | 10mg | $60 | 2021-12-16 | Buy |
| ApexBio Technology | A4037 | Vildagliptin(LAF-237) | 25mg | $100 | 2021-12-16 | Buy |
| ApexBio Technology | A4037 | Vildagliptin(LAF-237) | 50mg | $150 | 2021-12-16 | Buy |
Properties
Melting point :153-155?C
alpha :-78.3° (c = 9.73 in methanol)
Boiling point :531.3±50.0 °C(Predicted)
Density :1.27
Flash point :275.1℃
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 45 mg/ml), in DMF (up to 20 mg/ml), or in Ethanol (up to 20 mg/ml).
form :solid
pka :15.05±0.40(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO, DMF, or ethanol may be stored at -20°C for up to 3 months
InChI :InChI=1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12?,13?,14-,16?,17?/m0/s1
InChIKey :SYOKIDBDQMKNDQ-XWTIBIIYSA-N
SMILES :N1(C(CNC23CC4CC(CC(O)(C4)C2)C3)=O)CCC[C@H]1C#N
CAS DataBase Reference :274901-16-5(CAS DataBase Reference)
alpha :-78.3° (c = 9.73 in methanol)
Boiling point :531.3±50.0 °C(Predicted)
Density :1.27
Flash point :275.1℃
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 45 mg/ml), in DMF (up to 20 mg/ml), or in Ethanol (up to 20 mg/ml).
form :solid
pka :15.05±0.40(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO, DMF, or ethanol may be stored at -20°C for up to 3 months
InChI :InChI=1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12?,13?,14-,16?,17?/m0/s1
InChIKey :SYOKIDBDQMKNDQ-XWTIBIIYSA-N
SMILES :N1(C(CNC23CC4CC(CC(O)(C4)C2)C3)=O)CCC[C@H]1C#N
CAS DataBase Reference :274901-16-5(CAS DataBase Reference)
Safety Information
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Description
Glyptins are a class of oral antihyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. In addition to having use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Vildagliptin is an inhibitor of DPP-4 (IC50 = 3.5-34 nM). It also inhibits DPP-8 and DPP-9 (Ki = 810 and 95 nM, respectively) but not DPP-2 or the related fibroblast activation protein α. Through its effects on DPP-4, it blocks the degradation of several circulating peptides, including incretins (stimulators of insulin secretion) like glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1. Vildagliptin reduces fasting and postprandial glucose levels and decreases inflammatory and oxidative stress in diverse animal models of disease.More related product prices
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Suppliers and manufacturers
Capot Chemical Co.,Ltd.
Beijing Cooperate Pharmaceutical Co.,Ltd
