ZONISAMIDE-13C2-15N
- $396 - $2900
- Product name: ZONISAMIDE-13C2-15N
- CAS: 1188265-58-8
- MF: C8H8N2O3S
- MW: 215.25
- EINECS:
- MDL Number:MFCD08063551
- Synonyms:ZONISAMIDE-13C2-15N;13C2,15N]-Zonisamide
6 prices
Selected condition:
Brand
- Cayman Chemical
- Medical Isotopes, Inc.
- TRC
Package
- 1mg
- 5mg
- 10mg
- ManufacturerCayman Chemical
- Product number28807
- Product descriptionZonisamide-13C2,15N
- Packaging1mg
- Price$396
- Updated2024-03-01
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product numberCN100165
- Product descriptionZonisamid2-15C2-15N
- Packaging1mg
- Price$475
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product numberCN17154
- Product descriptionZonisamide-13C2,15N
- Packaging1mg
- Price$1750
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product numberCN100165
- Product descriptionZonisamid2-15C2-15N
- Packaging10mg
- Price$1800
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product numberCN17154
- Product descriptionZonisamide-13C2,15N
- Packaging5mg
- Price$2900
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberZ700003
- Product descriptionZonisamide-13C2-15N
- Packaging10mg
- Price$1980
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Cayman Chemical | 28807 | Zonisamide-13C2,15N | 1mg | $396 | 2024-03-01 | Buy |
Medical Isotopes, Inc. | CN100165 | Zonisamid2-15C2-15N | 1mg | $475 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | CN17154 | Zonisamide-13C2,15N | 1mg | $1750 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | CN100165 | Zonisamid2-15C2-15N | 10mg | $1800 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | CN17154 | Zonisamide-13C2,15N | 5mg | $2900 | 2021-12-16 | Buy |
TRC | Z700003 | Zonisamide-13C2-15N | 10mg | $1980 | 2021-12-16 | Buy |
Properties
Melting point :158 - 160°C
storage temp. :Refrigerator
solubility :DMSO (Sparingly), Methanol (Slightly)
form :Solid
color :Off-White to Light Yellow
storage temp. :Refrigerator
solubility :DMSO (Sparingly), Methanol (Slightly)
form :Solid
color :Off-White to Light Yellow
Safety Information
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Signal word: | Danger | ||||||||||||||||||||||
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Description
Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent. It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml. In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium current. Zonisamide inhibits H. pylori recombinant carbonic anhydrase (CA) and the human CA isoforms I, II, and V with Ki values of 218, 56, 35, and 21 nM, respectively. In mice, it has anticonvulsant activity against maximal electroshock seizure (MES) and pentylenetetrazole-induced maximal, but not minimal, seizures (ED50s = 19.6, 9.3, and >500 mg/kg, respectively). Zonisamide (40 mg/kg, p.o.) prevents MPTP-induced decreases in the levels of dopamine , but not homovanillic acid (HVA; ) or dihydroxyphenyl acetic acid (DOPAC; ), and increases MPTP-induced decreases in the dopamine turnover rate in mouse striatum in a model of Parkinson''s disease. Formulations containing zonisamide have been used in the treatment of partial seizures in adults with epilepsy.More related product prices
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