ChemicalBook CAS DataBase List (-)-1,2-BIS((2R,5R)-2,5-DIPHENYLPHOSPHOLANO)ETHANE

(-)-1,2-BIS((2R,5R)-2,5-DIPHENYLPHOSPHOLANO)ETHANE synthesis

1synthesis methods

Product Name:(-)-1,2-BIS((2R,5R)-2,5-DIPHENYLPHOSPHOLANO)ETHANE
CAS Number:528565-79-9
Molecular formula:C34H36P2
Molecular Weight:506.6

226393-33-5 Synthesis

Phospholane, 1-hydroxy-2,5-diphenyl-, 1-oxide, (2R,5R)-

226393-33-5
10 suppliers
inquiry

(-)-1,2-BIS((2R,5R)-2,5-DIPHENYLPHOSPHOLANO)ETHANE

528565-79-9
58 suppliers
$57.00/50mg

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: PhSiH₃ / toluene / 16 h / 110 °C
1.2: 95 percent / BH₃*SMe₂ / tetrahydrofuran / 16 h / 20 °C
2.1: nBuLi / tetrahydrofuran; hexane / 1 h / -20 °C
2.2: 69 percent / tetrahydrofuran; hexane / 40 h / 20 °C
3.1: 92 percent / HBF₄*OMe₂ / CH₂Cl₂ / 16 h / 20 °C

References:

Pilkington, Christopher J.;Zanotti-Gerosa, Antonio [Organic Letters,2003,vol. 5,# 8,p. 1273 - 1275]

FullText

(-)-1,2-BIS((2R,5R)-2,5-DIPHENYLPHOSPHOLANO)ETHANE Related Search:

(-)-1,2-BIS[(2R,5R)-2,5-DIMETHYLPHOSPHOLANO]BENZENE (S,S)-2,2-BIS(4-PHENYL-2-OXAZOLIN-2-YL)PROPANE (S,S)-2,6-BIS(4-ISOPROPYL-2-OXAZOLIN-2-YL)PYRIDINE