1,2-PROPADIENYLPHOSPHONIC ACID synthesis

Yield:34163-96-7 90 %

Reaction Conditions:

with water at 5 - 10;Green chemistry;

Steps:

1.2 2: Preparation of compound (II)

Under mechanical stirring,Add 1638mL of purified water into the 5L four-necked bottle,Cool the system down to 5-10°C,add 468 g of allenylphosphoryl chloride dropwise at a temperature of 5-10°C, it takes about 20 minutes,after the dropwise addition, keep warm at 10°C for 1h, add 1404ml of toluene to the system to extract the liquid separation, the toluene was discarded, purified water was concentrated under reduced pressure at 50°C until no distillate was produced. Concentrated and dry 200mL*2 times toluene with water to obtain 368g brown oily liquid,the molar yield is 90%.

References:

CN115677771,2023,A Location in patent:Paragraph 0028; 0033; 0037-0038; 0049-0050