1-(3-AMINOPHENYL)PYRROLIDIN-2-ONE synthesis
- Product Name:1-(3-AMINOPHENYL)PYRROLIDIN-2-ONE
- CAS Number:31992-43-5
- Molecular formula:C10H12N2O
- Molecular Weight:176.22
61372-79-0
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$28.60/50MG
31992-43-5
37 suppliers
$42.00/500mg
Yield:31992-43-5 100%
Reaction Conditions:
with hydrogen;palladium on activated carbon in ethanol at 20; under 2585.81 Torr; for 2 h;
Steps:
2
A suspension of 1-(3-nitrophenyl)pyrrolidin-2-one (3.0 g, 15 mmol) in ethanol (50 ml) was heated until complete solution was obtained. The solution was cooled to ambient temperature then treated with 10% palladium on charcoal (150 mg) and hydrogenated at 50 psi until hydrogen uptake ceased (ca. 2 hours). The mixture was filtered through a glass microfibre filter paper (Whatman GF/A) and evaporated to dryness to give 1-(3-aminophenyl)pyrrolidin-2-one as a pale green oil (2.6 g, 100%) which was used without purification.
References:
EP1214319,2003,B1 Location in patent:Page/Page column 14
585-79-5
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$15.00/1g
31992-43-5
37 suppliers
$42.00/500mg
99-09-2
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$14.00/1g
31992-43-5
37 suppliers
$42.00/500mg
13331-27-6
354 suppliers
$5.00/1g
31992-43-5
37 suppliers
$42.00/500mg
96-48-0
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$24.60/25g
108-45-2
466 suppliers
$13.00/25g
31992-43-5
37 suppliers
$42.00/500mg